My NCBISign In
RSS Settings
  • Search:

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

    Results: 1 to 20 of 994

    1.

    Are fish oil omega-3 long-chain fatty acids and their derivatives peroxisome proliferator-activated receptor agonists?

    Gani OA.

    Cardiovasc Diabetol. 2008 Mar 20;7:6.PMID: 18355413 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Peroxisome proliferator-activated receptors in vascular biology-molecular mechanisms and clinical implications.

    Touyz RM, Schiffrin EL.

    Vascul Pharmacol. 2006 Jul;45(1):19-28. Epub 2006 Jun 16. Review.PMID: 16782410 [PubMed - indexed for MEDLINE]Related articles

    3.

    Novel approach to treat insulin resistance, type 2 diabetes, and the metabolic syndrome: simultaneous activation of PPARalpha, PPARgamma, and PPARdelta.

    Evans JL, Lin JJ, Goldfine ID.

    Curr Diabetes Rev. 2005 Aug;1(3):299-307. Review.PMID: 18220606 [PubMed - indexed for MEDLINE]Related articles

    4.

    PPAR dual agonists: are they opening Pandora's Box?

    Balakumar P, Rose M, Ganti SS, Krishan P, Singh M.

    Pharmacol Res. 2007 Aug;56(2):91-8. Epub 2007 Mar 14. Review.PMID: 17428674 [PubMed - indexed for MEDLINE]Related articles

    5.

    Crystal structure of the peroxisome proliferator-activated receptor gamma (PPARgamma) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic pocket could be exploited for drug design.

    Montanari R, Saccoccia F, Scotti E, Crestani M, Godio C, Gilardi F, Loiodice F, Fracchiolla G, Laghezza A, Tortorella P, Lavecchia A, Novellino E, Mazza F, Aschi M, Pochetti G.

    J Med Chem. 2008 Dec 25;51(24):7768-76.PMID: 19053776 [PubMed - indexed for MEDLINE]Related articles

    6.

    P633H, a novel dual agonist at peroxisome proliferator-activated receptors alpha and gamma, with different anti-diabetic effects in db/db and KK-Ay mice.

    Chen W, Zhou XB, Liu HY, Xu C, Wang LL, Li S.

    Br J Pharmacol. 2009 Jul;157(5):724-35. Epub 2009 May 5.PMID: 19422369 [PubMed - indexed for MEDLINE]Related articles

    7.

    A rapid, homogeneous, fluorescence polarization binding assay for peroxisome proliferator-activated receptors alpha and gamma using a fluorescein-tagged dual PPARalpha/gamma activator.

    Seethala R, Golla R, Ma Z, Zhang H, O'Malley K, Lippy J, Cheng L, Mookhtiar K, Farrelly D, Zhang L, Hariharan N, Cheng PT.

    Anal Biochem. 2007 Apr 15;363(2):263-74. Epub 2007 Jan 28.PMID: 17335769 [PubMed - indexed for MEDLINE]Related articles

    8.

    Peroxisome proliferator-activated receptor alpha interacts with high affinity and is conformationally responsive to endogenous ligands.

    Hostetler HA, Petrescu AD, Kier AB, Schroeder F.

    J Biol Chem. 2005 May 13;280(19):18667-82. Epub 2005 Mar 16.PMID: 15774422 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Synthesis, biological evaluation, and molecular modeling investigation of new chiral fibrates with PPARalpha and PPARgamma agonist activity.

    Pinelli A, Godio C, Laghezza A, Mitro N, Fracchiolla G, Tortorella V, Lavecchia A, Novellino E, Fruchart JC, Staels B, Crestani M, Loiodice F.

    J Med Chem. 2005 Aug 25;48(17):5509-19.PMID: 16107150 [PubMed - indexed for MEDLINE]Related articles

    10.

    Molecular recognition of docosahexaenoic acid by peroxisome proliferator-activated receptors and retinoid-X receptor alpha.

    Gani OA, Sylte I.

    J Mol Graph Model. 2008 Sep;27(2):217-24. Epub 2008 Apr 29.PMID: 18547851 [PubMed - indexed for MEDLINE]Related articles

    11.

    Peroxisome proliferator-activated receptor (PPAR)-gamma positively controls and PPARalpha negatively controls cyclooxygenase-2 expression in rat brain astrocytes through a convergence on PPARbeta/delta via mutual control of PPAR expression levels.

    Aleshin S, Grabeklis S, Hanck T, Sergeeva M, Reiser G.

    Mol Pharmacol. 2009 Aug;76(2):414-24. Epub 2009 May 29.PMID: 19483106 [PubMed - indexed for MEDLINE]Related articles

    12.

    PAR-5359, a well-balanced PPARalpha/gamma dual agonist, exhibits equivalent antidiabetic and hypolipidemic activities in vitro and in vivo.

    Kim MK, Chae YN, Son MH, Kim SH, Kim JK, Moon HS, Park CS, Bae MH, Kim E, Han T, Choi HH, Shin YA, Ahn BN, Lee CH, Lim JI, Shin CY.

    Eur J Pharmacol. 2008 Oct 24;595(1-3):119-25. Epub 2008 Aug 12.PMID: 18727927 [PubMed - indexed for MEDLINE]Related articles

    13.

    Quantitative structure-activity relationship models with receptor-dependent descriptors for predicting peroxisome proliferator-activated receptor activities of thiazolidinedione and oxazolidinedione derivatives.

    Lather V, Kairys V, Fernandes MX.

    Chem Biol Drug Des. 2009 Apr;73(4):428-41. Epub 2009 Feb 21.PMID: 19243388 [PubMed - indexed for MEDLINE]Related articles

    14.

    Synthesis of docosahexaenoic acid derivatives designed as novel PPARgamma agonists and antidiabetic agents.

    Itoh T, Murota I, Yoshikai K, Yamada S, Yamamoto K.

    Bioorg Med Chem. 2006 Jan 1;14(1):98-108. Epub 2005 Sep 29.PMID: 16198578 [PubMed - indexed for MEDLINE]Related articles

    15.

    Structural determinants of the agonist-independent association of human peroxisome proliferator-activated receptors with coactivators.

    Molnár F, Matilainen M, Carlberg C.

    J Biol Chem. 2005 Jul 15;280(28):26543-56. Epub 2005 May 11.PMID: 15888456 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Sulfur-substituted and alpha-methylated fatty acids as peroxisome proliferator-activated receptor activators.

    Larsen LN, Granlund L, Holmeide AK, Skattebøl L, Nebb HI, Bremer J.

    Lipids. 2005 Jan;40(1):49-57.PMID: 15825830 [PubMed - indexed for MEDLINE]Related articles

    17.

    Ligand-induced stabilization and activation of peroxisome proliferator-activated receptor gamma.

    Gani OA, Sylte I.

    Chem Biol Drug Des. 2008 Jul;72(1):50-7. Epub 2008 Jun 11.PMID: 18554251 [PubMed - indexed for MEDLINE]Related articles

    18.

    Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells.

    Marx N, Duez H, Fruchart JC, Staels B.

    Circ Res. 2004 May 14;94(9):1168-78. Review.PMID: 15142970 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Structure of the PPARalpha and -gamma ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family.

    Cronet P, Petersen JF, Folmer R, Blomberg N, Sjöblom K, Karlsson U, Lindstedt EL, Bamberg K.

    Structure. 2001 Aug;9(8):699-706.PMID: 11587644 [PubMed - indexed for MEDLINE]Related articles

    20.

    T2384, a novel antidiabetic agent with unique peroxisome proliferator-activated receptor gamma binding properties.

    Li Y, Wang Z, Furukawa N, Escaron P, Weiszmann J, Lee G, Lindstrom M, Liu J, Liu X, Xu H, Plotnikova O, Prasad V, Walker N, Learned RM, Chen JL.

    J Biol Chem. 2008 Apr 4;283(14):9168-76. Epub 2008 Feb 7.PMID: 18263587 [PubMed - indexed for MEDLINE]Related articlesFree article

    Display Settings:

    Format
    Items per page
    Sort by

    Send to:

    Choose Destination

    Supplemental Content

    Filter your results:

    Find related data

    Recent activity

    You are here: NCBI > Literature > PubMed
    Write to the Help Desk