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Results: 1 to 20 of 110

1.

Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein.

Zerbinatti CV, Cordy JM, Chen CD, Guillily M, Suon S, Ray WJ, Seabrook GR, Abraham CR, Wolozin B.

Mol Neurodegener. 2008 Mar 18;3:5.PMID: 18348724 [PubMed - in process]Related articlesFree article

2.

Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on beta-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells.

Prasanthi JR, Huls A, Thomasson S, Thompson A, Schommer E, Ghribi O.

Mol Neurodegener. 2009 Jan 6;4:1.PMID: 19126211 [PubMed - in process]Related articlesFree article

3.

Inhibition of acyl-coenzyme A: cholesterol acyl transferase modulates amyloid precursor protein trafficking in the early secretory pathway.

Huttunen HJ, Peach C, Bhattacharyya R, Barren C, Pettingell W, Hutter-Paier B, Windisch M, Berezovska O, Kovacs DM.

FASEB J. 2009 Nov;23(11):3819-28. Epub 2009 Jul 22.PMID: 19625658 [PubMed - indexed for MEDLINE]Related articles

4.

Modulation of Abeta generation by small ubiquitin-like modifiers does not require conjugation to target proteins.

Dorval V, Mazzella MJ, Mathews PM, Hay RT, Fraser PE.

Biochem J. 2007 Jun 1;404(2):309-16.PMID: 17346237 [PubMed - indexed for MEDLINE]Related articlesFree article

5.

Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism.

Vetrivel KS, Gong P, Bowen JW, Cheng H, Chen Y, Carter M, Nguyen PD, Placanica L, Wieland FT, Li YM, Kounnas MZ, Thinakaran G.

Mol Neurodegener. 2007 Feb 8;2:4.PMID: 17288597 [PubMed]Related articlesFree article

6.

Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease.

Marzolo MP, Bu G.

Semin Cell Dev Biol. 2009 Apr;20(2):191-200. Epub 2008 Oct 17. Review.PMID: 19041409 [PubMed - indexed for MEDLINE]Related articles

7.

ApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity.

Fuentealba RA, Barría MI, Lee J, Cam J, Araya C, Escudero CA, Inestrosa NC, Bronfman FC, Bu G, Marzolo MP.

Mol Neurodegener. 2007 Jul 9;2:14.PMID: 17620134 [PubMed]Related articlesFree article

8.

Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport.

Xu Y, Liu Y, Ridgway ND, McMaster CR.

J Biol Chem. 2001 May 25;276(21):18407-14. Epub 2001 Feb 26.PMID: 11279184 [PubMed - indexed for MEDLINE]Related articlesFree article

9.

Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis.

Kyriazis GA, Wei Z, Vandermey M, Jo DG, Xin O, Mattson MP, Chan SL.

J Biol Chem. 2008 Sep 12;283(37):25492-502. Epub 2008 Jul 2.PMID: 18599481 [PubMed - indexed for MEDLINE]Related articlesFree article

10.

Oxysterols, cholesterol homeostasis, and Alzheimer disease.

Vaya J, Schipper HM.

J Neurochem. 2007 Sep;102(6):1727-37. Epub 2007 Jun 15. Review.PMID: 17573819 [PubMed - indexed for MEDLINE]Related articles

11.

Novel role of RanBP9 in BACE1 processing of amyloid precursor protein and amyloid beta peptide generation.

Lakshmana MK, Yoon IS, Chen E, Bianchi E, Koo EH, Kang DE.

J Biol Chem. 2009 May 1;284(18):11863-72. Epub 2009 Feb 27.PMID: 19251705 [PubMed - indexed for MEDLINE]Related articles

12.

Constitutively active Akt inhibits trafficking of amyloid precursor protein and amyloid precursor protein metabolites through feedback inhibition of phosphoinositide 3-kinase.

Shineman DW, Dain AS, Kim ML, Lee VM.

Biochemistry. 2009 May 5;48(17):3787-94.PMID: 19236051 [PubMed - indexed for MEDLINE]Related articles

13.

Membrane and protein interactions of oxysterols.

Massey JB.

Curr Opin Lipidol. 2006 Jun;17(3):296-301. Review.PMID: 16680036 [PubMed - indexed for MEDLINE]Related articles

14.

Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription.

Chen Y, Zhou K, Wang R, Liu Y, Kwak YD, Ma T, Thompson RC, Zhao Y, Smith L, Gasparini L, Luo Z, Xu H, Liao FF.

Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3907-12. Epub 2009 Feb 23.PMID: 19237574 [PubMed - indexed for MEDLINE]Related articlesFree article

15.

Suppression of APP-containing vesicle trafficking and production of beta-amyloid by AID/DHHC-12 protein.

Mizumaru C, Saito Y, Ishikawa T, Yoshida T, Yamamoto T, Nakaya T, Suzuki T.

J Neurochem. 2009 Dec;111(5):1213-24. Epub 2009 Sep 22.PMID: 19780898 [PubMed - indexed for MEDLINE]Related articles

16.

Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates beta-amyloid deposition through upregulating alpha-secretase in vivo and in vitro.

Mei Z, Zhang F, Tao L, Zheng W, Cao Y, Wang Z, Tang S, Le K, Chen S, Pi R, Liu P.

Neurosci Lett. 2009 Mar 13;452(2):90-5. Epub 2009 Jan 13.PMID: 19154776 [PubMed - indexed for MEDLINE]Related articles

17.

Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein.

Harris B, Pereira I, Parkin E.

Brain Res. 2009 Nov 3;1296:203-15. Epub 2009 Aug 11.PMID: 19679113 [PubMed - indexed for MEDLINE]Related articles

18.

Adaptor protein sorting nexin 17 regulates amyloid precursor protein trafficking and processing in the early endosomes.

Lee J, Retamal C, Cuitiño L, Caruano-Yzermans A, Shin JE, van Kerkhof P, Marzolo MP, Bu G.

J Biol Chem. 2008 Apr 25;283(17):11501-8. Epub 2008 Feb 13.PMID: 18276590 [PubMed - indexed for MEDLINE]Related articlesFree article

19.

The cholesterol transport inhibitor U18666a regulates amyloid precursor protein metabolism and trafficking in N2aAPP "Swedish" cells.

Davis W Jr.

Curr Alzheimer Res. 2008 Oct;5(5):448-56.PMID: 18855586 [PubMed - indexed for MEDLINE]Related articles

20.

Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease.

Dutescu RM, Li QX, Crowston J, Masters CL, Baird PN, Culvenor JG.

Graefes Arch Clin Exp Ophthalmol. 2009 Sep;247(9):1213-21. Epub 2009 Mar 7.PMID: 19271231 [PubMed - indexed for MEDLINE]Related articles

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