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    Results: 1 to 20 of 475

    1.

    5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy.

    Gubitosi-Klug RA, Talahalli R, Du Y, Nadler JL, Kern TS.

    Diabetes. 2008 May;57(5):1387-93. Epub 2008 Mar 17.PMID: 18346986 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Critical role of inducible nitric oxide synthase in degeneration of retinal capillaries in mice with streptozotocin-induced diabetes.

    Zheng L, Du Y, Miller C, Gubitosi-Klug RA, Ball S, Berkowitz BA, Kern TS.

    Diabetologia. 2007 Sep;50(9):1987-96. Epub 2007 Jun 22. Erratum in: Diabetologia. 2007 Oct;50(10):2228. PMID: 17583794 [PubMed - indexed for MEDLINE]Related articles

    3.

    Vascular damage in a mouse model of diabetic retinopathy: relation to neuronal and glial changes.

    Feit-Leichman RA, Kinouchi R, Takeda M, Fan Z, Mohr S, Kern TS, Chen DF.

    Invest Ophthalmol Vis Sci. 2005 Nov;46(11):4281-7.PMID: 16249509 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Oxidative damage in the retinal mitochondria of diabetic mice: possible protection by superoxide dismutase.

    Kanwar M, Chan PS, Kern TS, Kowluru RA.

    Invest Ophthalmol Vis Sci. 2007 Aug;48(8):3805-11.PMID: 17652755 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration.

    de Gooyer TE, Stevenson KA, Humphries P, Simpson DA, Gardiner TA, Stitt AW.

    Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5561-8.PMID: 17122149 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Retinal ischemia and reperfusion causes capillary degeneration: similarities to diabetes.

    Zheng L, Gong B, Hatala DA, Kern TS.

    Invest Ophthalmol Vis Sci. 2007 Jan;48(1):361-7.PMID: 17197555 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    The Ins2Akita mouse as a model of early retinal complications in diabetes.

    Barber AJ, Antonetti DA, Kern TS, Reiter CE, Soans RS, Krady JK, Levison SW, Gardner TW, Bronson SK.

    Invest Ophthalmol Vis Sci. 2005 Jun;46(6):2210-8.PMID: 15914643 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Inhibition of caspase-1/interleukin-1beta signaling prevents degeneration of retinal capillaries in diabetes and galactosemia.

    Vincent JA, Mohr S.

    Diabetes. 2007 Jan;56(1):224-30.PMID: 17192486 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Retinal vascular changes induced by the oxidative stress of alpha-tocopherol deficiency contrasted with diabetic microangiopathy.

    Robison WG Jr, Jacot JL, Katz ML, Glover JP.

    J Ocul Pharmacol Ther. 2000 Apr;16(2):109-20.PMID: 10803422 [PubMed - indexed for MEDLINE]Related articles

    10.

    A central role for inflammation in the pathogenesis of diabetic retinopathy.

    Joussen AM, Poulaki V, Le ML, Koizumi K, Esser C, Janicki H, Schraermeyer U, Kociok N, Fauser S, Kirchhof B, Kern TS, Adamis AP.

    FASEB J. 2004 Sep;18(12):1450-2. Epub 2004 Jul 1.PMID: 15231732 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Topical administration of nepafenac inhibits diabetes-induced retinal microvascular disease and underlying abnormalities of retinal metabolism and physiology.

    Kern TS, Miller CM, Du Y, Zheng L, Mohr S, Ball SL, Kim M, Jamison JA, Bingaman DP.

    Diabetes. 2007 Feb;56(2):373-9.PMID: 17259381 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.

    Poeckel D, Zemski Berry KA, Murphy RC, Funk CD.

    J Biol Chem. 2009 Jul 31;284(31):21077-89. Epub 2009 Jun 9.PMID: 19509298 [PubMed - indexed for MEDLINE]Related articles

    13.

    Increased basement membrane thickness, pericyte ghosts, and loss of retinal thickness and cells in dopamine beta hydroxylase knockout mice.

    Steinle JJ, Kern TS, Thomas SA, McFadyen-Ketchum LS, Smith CP.

    Exp Eye Res. 2009 Jun;88(6):1014-9. Epub 2009 Jan 7.PMID: 19176214 [PubMed - indexed for MEDLINE]Related articles

    14.

    Captopril inhibits capillary degeneration in the early stages of diabetic retinopathy.

    Zhang JZ, Xi X, Gao L, Kern TS.

    Curr Eye Res. 2007 Oct;32(10):883-9.PMID: 17963108 [PubMed - indexed for MEDLINE]Related articles

    15.

    Differential behavior of mesangial cells derived from 12/15-lipoxygenase knockout mice relative to control mice.

    Kim YS, Reddy MA, Lanting L, Adler SG, Natarajan R.

    Kidney Int. 2003 Nov;64(5):1702-14.PMID: 14531803 [PubMed - indexed for MEDLINE]Related articles

    16.

    Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-kappaB.

    Zheng L, Szabó C, Kern TS.

    Diabetes. 2004 Nov;53(11):2960-7.PMID: 15504977 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations.

    Joussen AM, Doehmen S, Le ML, Koizumi K, Radetzky S, Krohne TU, Poulaki V, Semkova I, Kociok N.

    Mol Vis. 2009 Jul 25;15:1418-28.PMID: 19641635 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Pericyte migration: a novel mechanism of pericyte loss in experimental diabetic retinopathy.

    Pfister F, Feng Y, vom Hagen F, Hoffmann S, Molema G, Hillebrands JL, Shani M, Deutsch U, Hammes HP.

    Diabetes. 2008 Sep;57(9):2495-502. Epub 2008 Jun 16.PMID: 18559662 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Inducible nitric oxide synthase isoform is a key mediator of leukostasis and blood-retinal barrier breakdown in diabetic retinopathy.

    Leal EC, Manivannan A, Hosoya K, Terasaki T, Cunha-Vaz J, Ambrósio AF, Forrester JV.

    Invest Ophthalmol Vis Sci. 2007 Nov;48(11):5257-65.PMID: 17962481 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Pericytes and the pathogenesis of diabetic retinopathy.

    Hammes HP, Lin J, Renner O, Shani M, Lundqvist A, Betsholtz C, Brownlee M, Deutsch U.

    Diabetes. 2002 Oct;51(10):3107-12.PMID: 12351455 [PubMed - indexed for MEDLINE]Related articlesFree article

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