PubMed

Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study.

Do R, Bailey SD, Desbiens K, Belisle A, Montpetit A, Bouchard C, Pérusse L, Vohl MC, Engert JC.

Diabetes. 2008 Apr;57(4):1147-50. Epub 2008 Mar 3.PMID: 18316358 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study.

Wing MR, Ziegler J, Langefeld CD, Ng MC, Haffner SM, Norris JM, Goodarzi MO, Bowden DW.

Hum Genet. 2009 Jun;125(5-6):615-26. Epub 2009 Mar 26.PMID: 19322589 [PubMed - indexed for MEDLINE]Related articles

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.

Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J, Najjar S, Nagaraja R, Orrú M, Usala G, Dei M, Lai S, Maschio A, Busonero F, Mulas A, Ehret GB, Fink AA, Weder AB, Cooper RS, Galan P, Chakravarti A, Schlessinger D, Cao A, Lakatta E, Abecasis GR.

PLoS Genet. 2007 Jul;3(7):e115.PMID: 17658951 [PubMed - indexed for MEDLINE]Related articlesFree article

Associations between glucose tolerance, insulin sensitivity and insulin secretion phenotypes and polymorphisms in adiponectin and adiponectin receptor genes in the Quebec Family Study.

Ruchat SM, Loos RJ, Rankinen T, Vohl MC, Weisnagel SJ, Després JP, Bouchard C, Pérusse L.

Diabet Med. 2008 Apr;25(4):400-6. Epub 2008 Feb 18.PMID: 18294218 [PubMed - indexed for MEDLINE]Related articles

The FTO gene is associated with adulthood obesity in the Mexican population.

Villalobos-Comparán M, Teresa Flores-Dorantes M, Teresa Villarreal-Molina M, Rodríguez-Cruz M, García-Ulloa AC, Robles L, Huertas-Vázquez A, Saucedo-Villarreal N, López-Alarcón M, Sánchez-Muñoz F, Domínguez-López A, Gutiérrez-Aguilar R, Menjivar M, Coral-Vázquez R, Hernández-Stengele G, Vital-Reyes VS, Acuña-Alonzo V, Romero-Hidalgo S, Ruiz-Gómez DG, Riaño-Barros D, Herrera MF, Gómez-Pérez FJ, Froguel P, García-García E, Teresa Tusié-Luna M, Aguilar-Salinas CA, Canizales-Quinteros S.

Obesity (Silver Spring). 2008 Oct;16(10):2296-301. Epub 2008 Jul 31.PMID: 18719664 [PubMed - indexed for MEDLINE]Related articles

Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation.

Andreasen CH, Stender-Petersen KL, Mogensen MS, Torekov SS, Wegner L, Andersen G, Nielsen AL, Albrechtsen A, Borch-Johnsen K, Rasmussen SS, Clausen JO, Sandbaek A, Lauritzen T, Hansen L, Jørgensen T, Pedersen O, Hansen T.

Diabetes. 2008 Jan;57(1):95-101. Epub 2007 Oct 17.PMID: 17942823 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin and adiponectin receptor gene variants in relation to resting metabolic rate, respiratory quotient, and adiposity-related phenotypes in the Quebec Family Study.

Loos RJ, Ruchat S, Rankinen T, Tremblay A, Pérusse L, Bouchard C.

Am J Clin Nutr. 2007 Jan;85(1):26-34.PMID: 17209173 [PubMed - indexed for MEDLINE]Related articlesFree article

Variants in the fat mass- and obesity-associated (FTO) gene are not associated with obesity in a Chinese Han population.

Li H, Wu Y, Loos RJ, Hu FB, Liu Y, Wang J, Yu Z, Lin X.

Diabetes. 2008 Jan;57(1):264-8. Epub 2007 Oct 24.PMID: 17959933 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associated phenotypes in the French population.

Cheyssac C, Lecoeur C, Dechaume A, Bibi A, Charpentier G, Balkau B, Marre M, Froguel P, Gibson F, Vaxillaire M.

BMC Med Genet. 2006 May 5;7:44.PMID: 16677372 [PubMed - indexed for MEDLINE]Related articlesFree article

INSIG2 SNPs associated with obesity and glucose homeostasis traits in Hispanics: the IRAS Family Study.

Talbert ME, Langefeld CD, Ziegler JT, Haffner SM, Norris JM, Bowden DW.

Obesity (Silver Spring). 2009 Aug;17(8):1554-62. Epub 2009 Apr 9.PMID: 19360016 [PubMed - indexed for MEDLINE]Related articles

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI.

Freathy RM, Timpson NJ, Lawlor DA, Pouta A, Ben-Shlomo Y, Ruokonen A, Ebrahim S, Shields B, Zeggini E, Weedon MN, Lindgren CM, Lango H, Melzer D, Ferrucci L, Paolisso G, Neville MJ, Karpe F, Palmer CN, Morris AD, Elliott P, Jarvelin MR, Smith GD, McCarthy MI, Hattersley AT, Frayling TM.

Diabetes. 2008 May;57(5):1419-26. Epub 2008 Mar 17.PMID: 18346983 [PubMed - indexed for MEDLINE]Related articlesFree article

Combined effects of MC4R and FTO common genetic variants on obesity in European general populations.

Cauchi S, Stutzmann F, Cavalcanti-Proença C, Durand E, Pouta A, Hartikainen AL, Marre M, Vol S, Tammelin T, Laitinen J, Gonzalez-Izquierdo A, Blakemore AI, Elliott P, Meyre D, Balkau B, Järvelin MR, Froguel P.

J Mol Med. 2009 May;87(5):537-46. Epub 2009 Mar 3.PMID: 19255736 [PubMed - indexed for MEDLINE]Related articles

Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss.

Haupt A, Thamer C, Machann J, Kirchhoff K, Stefan N, Tschritter O, Machicao F, Schick F, Häring HU, Fritsche A.

Obesity (Silver Spring). 2008 Aug;16(8):1969-72. Epub 2008 May 29.PMID: 18535549 [PubMed - indexed for MEDLINE]Related articles

Human resistin gene polymorphism is associated with visceral obesity and fasting and oral glucose stimulated C-peptide in the Québec Family Study.

Bouchard L, Weisnagel SJ, Engert JC, Hudson TJ, Bouchard C, Vohl MC, Pérusse L.

J Endocrinol Invest. 2004 Dec;27(11):1003-9.PMID: 15754730 [PubMed - indexed for MEDLINE]Related articles

A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome.

Menzaghi C, Ercolino T, Di Paola R, Berg AH, Warram JH, Scherer PE, Trischitta V, Doria A.

Diabetes. 2002 Jul;51(7):2306-12.PMID: 12086965 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms near SOCS3 are associated with obesity and glucose homeostasis traits in Hispanic Americans from the Insulin Resistance Atherosclerosis Family Study.

Talbert ME, Langefeld CD, Ziegler J, Mychaleckyj JC, Haffner SM, Norris JM, Bowden DW.

Hum Genet. 2009 Mar;125(2):153-62. Epub 2008 Dec 13.PMID: 19083014 [PubMed - indexed for MEDLINE]Related articles

Polymorphism of the tumor necrosis factor-alpha receptor 2 gene is associated with obesity, leptin levels, and insulin resistance in young subjects and diet-treated type 2 diabetic patients.

Fernández-Real JM, Vendrell J, Ricart W, Broch M, Gutiérrez C, Casamitjana R, Oriola J, Richart C.

Diabetes Care. 2000 Jun;23(6):831-7.PMID: 10841005 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of variants in the fat mass and obesity associated (FTO) gene with polycystic ovary syndrome.

Barber TM, Bennett AJ, Groves CJ, Sovio U, Ruokonen A, Martikainen H, Pouta A, Hartikainen AL, Elliott P, Lindgren CM, Freathy RM, Koch K, Ouwehand WH, Karpe F, Conway GS, Wass JA, Järvelin MR, Franks S, McCarthy MI.

Diabetologia. 2008 Jul;51(7):1153-8. Epub 2008 May 14.PMID: 18478198 [PubMed - indexed for MEDLINE]Related articles

FTO gene variants are strongly associated with type 2 diabetes in South Asian Indians.

Yajnik CS, Janipalli CS, Bhaskar S, Kulkarni SR, Freathy RM, Prakash S, Mani KR, Weedon MN, Kale SD, Deshpande J, Krishnaveni GV, Veena SR, Fall CH, McCarthy MI, Frayling TM, Hattersley AT, Chandak GR.

Diabetologia. 2009 Feb;52(2):247-52. Epub 2008 Nov 13.PMID: 19005641 [PubMed - indexed for MEDLINE]Related articlesFree article

Physical activity and the association of common FTO gene variants with body mass index and obesity.

Rampersaud E, Mitchell BD, Pollin TI, Fu M, Shen H, O'Connell JR, Ducharme JL, Hines S, Sack P, Naglieri R, Shuldiner AR, Snitker S.

Arch Intern Med. 2008 Sep 8;168(16):1791-7. Erratum in: Arch Intern Med. 2009 Mar 9;169(5):453. PMID: 18779467 [PubMed - indexed for MEDLINE]Related articlesFree article