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    Results: 1 to 20 of 352

    1.

    Malonyl CoenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle.

    Bouzakri K, Austin R, Rune A, Lassman ME, Garcia-Roves PM, Berger JP, Krook A, Chibalin AV, Zhang BB, Zierath JR.

    Diabetes. 2008 Jun;57(6):1508-16. Epub 2008 Feb 26.PMID: 18314420 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle.

    Austin RL, Rune A, Bouzakri K, Zierath JR, Krook A.

    Diabetes. 2008 Aug;57(8):2066-73. Epub 2008 Apr 28.PMID: 18443205 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Characterization of rat liver malonyl-CoA decarboxylase and the study of its role in regulating fatty acid metabolism.

    Dyck JR, Berthiaume LG, Thomas PD, Kantor PF, Barr AJ, Barr R, Singh D, Hopkins TA, Voilley N, Prentki M, Lopaschuk GD.

    Biochem J. 2000 Sep 1;350 Pt 2:599-608.PMID: 10947976 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Prolonged exposure to palmitate impairs fatty acid oxidation despite activation of AMP-activated protein kinase in skeletal muscle cells.

    Pimenta AS, Gaidhu MP, Habib S, So M, Fediuc S, Mirpourian M, Musheev M, Curi R, Ceddia RB.

    J Cell Physiol. 2008 Nov;217(2):478-85.PMID: 18561258 [PubMed - indexed for MEDLINE]Related articles

    5.

    Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle.

    Al-Khalili L, Bouzakri K, Glund S, Lönnqvist F, Koistinen HA, Krook A.

    Mol Endocrinol. 2006 Dec;20(12):3364-75. Epub 2006 Aug 31.PMID: 16945991 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Eicosapentaenoic acid (20:5 n-3) increases fatty acid and glucose uptake in cultured human skeletal muscle cells.

    Aas V, Rokling-Andersen MH, Kase ET, Thoresen GH, Rustan AC.

    J Lipid Res. 2006 Feb;47(2):366-74. Epub 2005 Nov 21.PMID: 16301737 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle.

    Bouzakri K, Zachrisson A, Al-Khalili L, Zhang BB, Koistinen HA, Krook A, Zierath JR.

    Cell Metab. 2006 Jul;4(1):89-96.PMID: 16814735 [PubMed - indexed for MEDLINE]Related articles

    8.

    A role for peroxisome proliferator-activated receptor alpha (PPARalpha ) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated with higher concentrations of malonyl-CoA and reduced expression of malonyl-CoA decarboxylase.

    Campbell FM, Kozak R, Wagner A, Altarejos JY, Dyck JR, Belke DD, Severson DL, Kelly DP, Lopaschuk GD.

    J Biol Chem. 2002 Feb 8;277(6):4098-103. Epub 2001 Dec 4.PMID: 11734553 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation.

    Dyck JR, Cheng JF, Stanley WC, Barr R, Chandler MP, Brown S, Wallace D, Arrhenius T, Harmon C, Yang G, Nadzan AM, Lopaschuk GD.

    Circ Res. 2004 May 14;94(9):e78-84. Epub 2004 Apr 22.PMID: 15105298 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Regulation of cardiac and skeletal muscle malonyl-CoA decarboxylase by fatty acids.

    Young ME, Goodwin GW, Ying J, Guthrie P, Wilson CR, Laws FA, Taegtmeyer H.

    Am J Physiol Endocrinol Metab. 2001 Mar;280(3):E471-9.PMID: 11171602 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    MCD encodes peroxisomal and cytoplasmic forms of malonyl-CoA decarboxylase and is mutated in malonyl-CoA decarboxylase deficiency.

    Sacksteder KA, Morrell JC, Wanders RJ, Matalon R, Gould SJ.

    J Biol Chem. 1999 Aug 27;274(35):24461-8.PMID: 10455107 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation.

    Perdomo G, Commerford SR, Richard AM, Adams SH, Corkey BE, O'Doherty RM, Brown NF.

    J Biol Chem. 2004 Jun 25;279(26):27177-86. Epub 2004 Apr 22.PMID: 15105415 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites.

    Lee JS, Pinnamaneni SK, Eo SJ, Cho IH, Pyo JH, Kim CK, Sinclair AJ, Febbraio MA, Watt MJ.

    J Appl Physiol. 2006 May;100(5):1467-74. Epub 2005 Dec 15.PMID: 16357064 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance.

    Bouzakri K, Zierath JR.

    J Biol Chem. 2007 Mar 16;282(11):7783-9. Epub 2007 Jan 16.PMID: 17227768 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects.

    Bandyopadhyay GK, Yu JG, Ofrecio J, Olefsky JM.

    Diabetes. 2006 Aug;55(8):2277-85.PMID: 16873691 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Differential contribution of insulin receptor substrates 1 versus 2 to insulin signaling and glucose uptake in l6 myotubes.

    Huang C, Thirone AC, Huang X, Klip A.

    J Biol Chem. 2005 May 13;280(19):19426-35. Epub 2005 Mar 11.PMID: 15764603 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli.

    Roduit R, Nolan C, Alarcon C, Moore P, Barbeau A, Delghingaro-Augusto V, Przybykowski E, Morin J, Massé F, Massie B, Ruderman N, Rhodes C, Poitout V, Prentki M.

    Diabetes. 2004 Apr;53(4):1007-19.PMID: 15047616 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance.

    Koves TR, Ussher JR, Noland RC, Slentz D, Mosedale M, Ilkayeva O, Bain J, Stevens R, Dyck JR, Newgard CB, Lopaschuk GD, Muoio DM.

    Cell Metab. 2008 Jan;7(1):45-56.PMID: 18177724 [PubMed - indexed for MEDLINE]Related articles

    19.

    Expression of genes regulating malonyl-CoA in human skeletal muscle.

    Pender C, Trentadue AR, Pories WJ, Dohm GL, Houmard JA, Youngren JF.

    J Cell Biochem. 2006 Oct 15;99(3):860-7.PMID: 16721829 [PubMed - indexed for MEDLINE]Related articles

    20.

    Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro.

    Pinnamaneni SK, Southgate RJ, Febbraio MA, Watt MJ.

    Diabetologia. 2006 Dec;49(12):3027-37. Epub 2006 Oct 11.PMID: 17033839 [PubMed - indexed for MEDLINE]Related articles

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