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    Results: 1 to 20 of 942

    1.

    Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1.

    Bachmakov I, Glaeser H, Fromm MF, König J.

    Diabetes. 2008 Jun;57(6):1463-9. Epub 2008 Feb 26.PMID: 18314419 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.

    Noé J, Portmann R, Brun ME, Funk C.

    Drug Metab Dispos. 2007 Aug;35(8):1308-14. Epub 2007 Apr 30.PMID: 17470528 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3.

    Seithel A, Eberl S, Singer K, Auge D, Heinkele G, Wolf NB, Dörje F, Fromm MF, König J.

    Drug Metab Dispos. 2007 May;35(5):779-86. Epub 2007 Feb 12.PMID: 17296622 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    In vitro evidence for the role of OATP and OCT uptake transporters in drug-drug interactions.

    Kindla J, Fromm MF, König J.

    Expert Opin Drug Metab Toxicol. 2009 May;5(5):489-500. Review.PMID: 19416085 [PubMed - indexed for MEDLINE]Related articles

    5.

    Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver.

    Vavricka SR, Van Montfoort J, Ha HR, Meier PJ, Fattinger K.

    Hepatology. 2002 Jul;36(1):164-72.PMID: 12085361 [PubMed - indexed for MEDLINE]Related articles

    6.

    Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin II receptor antagonist, in humans.

    Ishiguro N, Maeda K, Kishimoto W, Saito A, Harada A, Ebner T, Roth W, Igarashi T, Sugiyama Y.

    Drug Metab Dispos. 2006 Jul;34(7):1109-15. Epub 2006 Apr 12.PMID: 16611857 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Drug-drug interaction between pitavastatin and various drugs via OATP1B1.

    Hirano M, Maeda K, Shitara Y, Sugiyama Y.

    Drug Metab Dispos. 2006 Jul;34(7):1229-36. Epub 2006 Apr 4.PMID: 16595711 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide.

    Ishiguro N, Maeda K, Saito A, Kishimoto W, Matsushima S, Ebner T, Roth W, Igarashi T, Sugiyama Y.

    Drug Metab Dispos. 2008 Apr;36(4):796-805. Epub 2008 Jan 7.PMID: 18180273 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor.

    Yamada A, Maeda K, Kamiyama E, Sugiyama D, Kondo T, Shiroyanagi Y, Nakazawa H, Okano T, Adachi M, Schuetz JD, Adachi Y, Hu Z, Kusuhara H, Sugiyama Y.

    Drug Metab Dispos. 2007 Dec;35(12):2166-76. Epub 2007 Sep 6.PMID: 17823233 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans.

    Yamashiro W, Maeda K, Hirouchi M, Adachi Y, Hu Z, Sugiyama Y.

    Drug Metab Dispos. 2006 Jul;34(7):1247-54. Epub 2006 Apr 19.PMID: 16624871 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.

    Gui C, Miao Y, Thompson L, Wahlgren B, Mock M, Stieger B, Hagenbuch B.

    Eur J Pharmacol. 2008 Apr 14;584(1):57-65. Epub 2008 Feb 8.PMID: 18321482 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Transporters as a determinant of drug clearance and tissue distribution.

    Shitara Y, Horie T, Sugiyama Y.

    Eur J Pharm Sci. 2006 Apr;27(5):425-46. Epub 2006 Feb 20. Review.PMID: 16488580 [PubMed - indexed for MEDLINE]Related articles

    13.

    Hepatic uptake and excretion of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a novel if channel inhibitor, in rats and humans.

    Umehara K, Iwai M, Adachi Y, Iwatsubo T, Usui T, Kamimura H.

    Drug Metab Dispos. 2008 Jun;36(6):1030-8. Epub 2008 Mar 10.PMID: 18332079 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil.

    Treiber A, Schneiter R, Häusler S, Stieger B.

    Drug Metab Dispos. 2007 Aug;35(8):1400-7. Epub 2007 May 11.PMID: 17496208 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Predominant contribution of rat organic anion transporting polypeptide-2 (Oatp2) to hepatic uptake of beta-lactam antibiotics.

    Nakakariya M, Shimada T, Irokawa M, Koibuchi H, Iwanaga T, Yabuuchi H, Maeda T, Tamai I.

    Pharm Res. 2008 Mar;25(3):578-85. Epub 2007 Sep 22.PMID: 17891554 [PubMed - indexed for MEDLINE]Related articles

    16.

    Functional involvement of organic cation transporter1 (OCT1/Oct1) in the hepatic uptake of organic cations in humans and rats.

    Umehara KI, Iwatsubo T, Noguchi K, Kamimura H.

    Xenobiotica. 2007 Aug;37(8):818-31.PMID: 17701831 [PubMed - indexed for MEDLINE]Related articles

    17.

    Uptake of ursodeoxycholate and its conjugates by human hepatocytes: role of Na(+)-taurocholate cotransporting polypeptide (NTCP), organic anion transporting polypeptide (OATP) 1B1 (OATP-C), and oatp1B3 (OATP8).

    Maeda K, Kambara M, Tian Y, Hofmann AF, Sugiyama Y.

    Mol Pharm. 2006 Jan-Feb;3(1):70-7.PMID: 16686371 [PubMed - indexed for MEDLINE]Related articles

    18.

    The organic anion transport polypeptide 1d1 (Oatp1d1) mediates hepatocellular uptake of phalloidin and microcystin into skate liver.

    Meier-Abt F, Hammann-Hänni A, Stieger B, Ballatori N, Boyer JL.

    Toxicol Appl Pharmacol. 2007 Feb 1;218(3):274-9. Epub 2006 Nov 21.PMID: 17198718 [PubMed - indexed for MEDLINE]Related articles

    19.

    Pharmacogenetics of OATP (SLC21/SLCO), OAT and OCT (SLC22) and PEPT (SLC15) transporters in the intestine, liver and kidney.

    Zaïr ZM, Eloranta JJ, Stieger B, Kullak-Ublick GA.

    Pharmacogenomics. 2008 May;9(5):597-624. Review.PMID: 18466105 [PubMed - indexed for MEDLINE]Related articles

    20.

    Functional differences in steroid sulfate uptake of organic anion transporter 4 (OAT4) and organic anion transporting polypeptide 2B1 (OATP2B1) in human placenta.

    Ugele B, Bahn A, Rex-Haffner M.

    J Steroid Biochem Mol Biol. 2008 Jul;111(1-2):1-6. Epub 2008 Apr 11.PMID: 18501590 [PubMed - indexed for MEDLINE]Related articles

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