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    Results: 1 to 20 of 105

    1.

    Performance of AAV8 vectors expressing human factor IX from a hepatic-selective promoter following intravenous injection into rats.

    Graham T, McIntosh J, Work LM, Nathwani A, Baker AH.

    Genet Vaccines Ther. 2008 Mar 3;6:9.PMID: 18312698 [PubMed - in process]Related articlesFree article

    2.

    Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy.

    Jiang H, Couto LB, Patarroyo-White S, Liu T, Nagy D, Vargas JA, Zhou S, Scallan CD, Sommer J, Vijay S, Mingozzi F, High KA, Pierce GF.

    Blood. 2006 Nov 15;108(10):3321-8. Epub 2006 Jul 25.PMID: 16868252 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Efficient induction of immune tolerance to coagulation factor IX following direct intramuscular gene transfer.

    Cohn EF, Zhuo J, Kelly ME, Chao HJ.

    J Thromb Haemost. 2007 Jun;5(6):1227-36.PMID: 17362228 [PubMed - indexed for MEDLINE]Related articles

    4.

    Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates.

    Nathwani AC, Gray JT, McIntosh J, Ng CY, Zhou J, Spence Y, Cochrane M, Gray E, Tuddenham EG, Davidoff AM.

    Blood. 2007 Feb 15;109(4):1414-21. Epub 2006 Nov 7.PMID: 17090654 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose.

    Wu Z, Sun J, Zhang T, Yin C, Yin F, Van Dyke T, Samulski RJ, Monahan PE.

    Mol Ther. 2008 Feb;16(2):280-9. Epub 2007 Dec 4.PMID: 18059373 [PubMed - indexed for MEDLINE]Related articles

    6.

    Skeletal muscle-specific expression of human blood coagulation factor IX rescues factor IX deficiency mouse by AAV-mediated gene transfer.

    Lai L, Chen L, Wang J, Zhou H, Lu D, Wang Q, Gao X, Qiu X, Xue J.

    Sci China C Life Sci. 1999 Dec;42(6):628-34.PMID: 18726486 [PubMed]Related articles

    7.

    Overexpression of indoleamine dioxygenase in rat liver allografts using a high-efficiency adeno-associated virus vector does not prevent acute rejection.

    Laurence JM, Wang C, Zheng M, Cunningham S, Earl J, Tay SS, Allen RD, McCaughan GW, Alexander IE, Bishop GA, Sharland AF.

    Liver Transpl. 2009 Feb;15(2):233-41.PMID: 19177450 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Evidence of multiyear factor IX expression by AAV-mediated gene transfer to skeletal muscle in an individual with severe hemophilia B.

    Jiang H, Pierce GF, Ozelo MC, de Paula EV, Vargas JA, Smith P, Sommer J, Luk A, Manno CS, High KA, Arruda VR.

    Mol Ther. 2006 Sep;14(3):452-5. Epub 2006 Jul 5.PMID: 16822719 [PubMed - indexed for MEDLINE]Related articles

    9.

    Efficient delivery of human clotting factor IX after injection of lentiviral vectors in utero.

    Chen XG, Zhu HZ, Gong JL, Li F, Xue JL.

    Acta Pharmacol Sin. 2004 Jun;25(6):789-93.PMID: 15169633 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Intraarticular factor IX protein or gene replacement protects against development of hemophilic synovitis in the absence of circulating factor IX.

    Sun J, Hakobyan N, Valentino LA, Feldman BL, Samulski RJ, Monahan PE.

    Blood. 2008 Dec 1;112(12):4532-41. Epub 2008 Aug 20.PMID: 18716130 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy.

    Uchibori R, Okada T, Ito T, Urabe M, Mizukami H, Kume A, Ozawa K.

    J Gene Med. 2009 May;11(5):373-81.PMID: 19274675 [PubMed - indexed for MEDLINE]Related articles

    12.

    In utero gene transfer of human factor IX to fetal mice can induce postnatal tolerance of the exogenous clotting factor.

    Waddington SN, Buckley SM, Nivsarkar M, Jezzard S, Schneider H, Dahse T, Kemball-Cook G, Miah M, Tucker N, Dallman MJ, Themis M, Coutelle C.

    Blood. 2003 Feb 15;101(4):1359-66. Epub 2002 Oct 3. Erratum in: Blood. 2006 Mar 1;107(5):1750. PMID: 12393743 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Transient expression of genes delivered to newborn rat liver using recombinant adeno-associated virus 2/8 vectors.

    Flageul M, Aubert D, Pichard V, Nguyen TH, Nowrouzi A, Schmidt M, Ferry N.

    J Gene Med. 2009 Aug;11(8):689-96.PMID: 19455564 [PubMed - indexed for MEDLINE]Related articles

    14.

    Enhancing transduction of the liver by adeno-associated viral vectors.

    Nathwani AC, Cochrane M, McIntosh J, Ng CY, Zhou J, Gray JT, Davidoff AM.

    Gene Ther. 2009 Jan;16(1):60-9. Epub 2008 Aug 14.PMID: 18701909 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Gene therapy following subretinal AAV5 vector delivery is not affected by a previous intravitreal AAV5 vector administration in the partner eye.

    Li W, Kong F, Li X, Dai X, Liu X, Zheng Q, Wu R, Zhou X, Lü F, Chang B, Li Q, Hauswirth WW, Qu J, Pang JJ.

    Mol Vis. 2009;15:267-75. Epub 2009 Feb 6.PMID: 19190735 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    [Non-viral gene transfer results in therapeutic factor IX levels in haemophilia B mice]

    Schüttrumpf J, Milanov P, Roth S, Seifried E, Tonn T.

    Hamostaseologie. 2008 Oct;28 Suppl 1:S92-5. German. PMID: 18958345 [PubMed - indexed for MEDLINE]Related articles

    17.

    Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat.

    Bish LT, Morine K, Sleeper MM, Sanmiguel J, Wu D, Gao G, Wilson JM, Sweeney HL.

    Hum Gene Ther. 2008 Dec;19(12):1359-68.PMID: 18795839 [PubMed - indexed for MEDLINE]Related articles

    18.

    Biochemical correction of short-chain acyl-coenzyme A dehydrogenase deficiency after portal vein injection of rAAV8-SCAD.

    Beattie SG, Goetzman E, Conlon T, Germain S, Walter G, Campbell-Thompson M, Matern D, Vockley J, Flotte TR.

    Hum Gene Ther. 2008 Jun;19(6):579-88.PMID: 18500942 [PubMed - indexed for MEDLINE]Related articles

    19.

    Induction of immune tolerance to FIX following muscular AAV gene transfer is AAV-dose/FIX-level dependent.

    Kelly ME, Zhuo J, Bharadwaj AS, Chao H.

    Mol Ther. 2009 May;17(5):857-63. Epub 2009 Feb 24.PMID: 19240690 [PubMed - indexed for MEDLINE]Related articles

    20.

    AAV-mediated gene transfer for the treatment of hemophilia B: problems and prospects.

    Hasbrouck NC, High KA.

    Gene Ther. 2008 Jun;15(11):870-5. Epub 2008 Apr 24. Review.PMID: 18432276 [PubMed - indexed for MEDLINE]Related articles

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