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    Results: 1 to 20 of 759

    1.

    PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes.

    Smyth DJ, Cooper JD, Howson JM, Walker NM, Plagnol V, Stevens H, Clayton DG, Todd JA.

    Diabetes. 2008 Jun;57(6):1730-7. Epub 2008 Feb 27.PMID: 18305142 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Further evidence of a primary, causal association of the PTPN22 620W variant with type 1 diabetes.

    Zoledziewska M, Perra C, Orrù V, Moi L, Frongia P, Congia M, Bottini N, Cucca F.

    Diabetes. 2008 Jan;57(1):229-34. Epub 2007 Oct 12.PMID: 17934143 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Systematic search for single nucleotide polymorphisms in a lymphoid tyrosine phosphatase gene (PTPN22): association between a promoter polymorphism and type 1 diabetes in Asian populations.

    Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Uga M, Kurihara S, Kawabata Y, Tanaka S, Kanazawa Y, Lee I, Eguchi K.

    Am J Med Genet A. 2006 Mar 15;140(6):586-93. Erratum in: Am J Med Genet A. 2007 Aug 1;143(15):18212-3. Uga, Mho [corrected to Uga, Miho]. PMID: 16470599 [PubMed - indexed for MEDLINE]Related articles

    4.

    No independent role of the -1123 G>C and+2740 A>G variants in the association of PTPN22 with type 1 diabetes and juvenile idiopathic arthritis in two Caucasian populations.

    Cinek O, Hradsky O, Ahmedov G, Slavcev A, Kolouskova S, Kulich M, Sumnik Z.

    Diabetes Res Clin Pract. 2007 May;76(2):297-303. Epub 2006 Sep 26.PMID: 17000021 [PubMed - indexed for MEDLINE]Related articles

    5.

    Associations of protein tyrosine phosphatase nonreceptor 22 (PTPN22) gene polymorphisms with susceptibility to Graves' disease in a Japanese population.

    Ichimura M, Kaku H, Fukutani T, Koga H, Mukai T, Miyake I, Yamada K, Koda Y, Hiromatsu Y.

    Thyroid. 2008 Jun;18(6):625-30.PMID: 18578611 [PubMed - indexed for MEDLINE]Related articles

    6.

    The protein tyrosine phosphatase nonreceptor 22 (PTPN22) is associated with high GAD antibody titer in latent autoimmune diabetes in adults: Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study 3.

    Petrone A, Suraci C, Capizzi M, Giaccari A, Bosi E, Tiberti C, Cossu E, Pozzilli P, Falorni A, Buzzetti R; NIRAD Study Group.

    Diabetes Care. 2008 Mar;31(3):534-8. Epub 2007 Dec 4.PMID: 18056891 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus.

    Smyth D, Cooper JD, Collins JE, Heward JM, Franklyn JA, Howson JM, Vella A, Nutland S, Rance HE, Maier L, Barratt BJ, Guja C, Ionescu-Tîrgoviste C, Savage DA, Dunger DB, Widmer B, Strachan DP, Ring SM, Walker N, Clayton DG, Twells RC, Gough SC, Todd JA.

    Diabetes. 2004 Nov;53(11):3020-3.PMID: 15504986 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes.

    Bjørnvold M, Undlien DE, Joner G, Dahl-Jørgensen K, Njølstad PR, Akselsen HE, Gervin K, Rønningen KS, Stene LC.

    Diabetologia. 2008 Apr;51(4):589-96. Epub 2008 Feb 22.PMID: 18292987 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Association of PTPN22 haplotypes with Graves' disease.

    Heward JM, Brand OJ, Barrett JC, Carr-Smith JD, Franklyn JA, Gough SC.

    J Clin Endocrinol Metab. 2007 Feb;92(2):685-90. Epub 2006 Dec 5.PMID: 17148556 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes.

    Hermann R, Lipponen K, Kiviniemi M, Kakko T, Veijola R, Simell O, Knip M, Ilonen J.

    Diabetologia. 2006 Jun;49(6):1198-208. Epub 2006 Apr 14.PMID: 16614815 [PubMed - indexed for MEDLINE]Related articles

    11.

    Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes.

    Cervin C, Lyssenko V, Bakhtadze E, Lindholm E, Nilsson P, Tuomi T, Cilio CM, Groop L.

    Diabetes. 2008 May;57(5):1433-7. Epub 2008 Feb 29.PMID: 18310307 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Role of HLA-DRB1 and PTPN22 genes in susceptibility to juvenile idiopathic arthritis in Hungarian patients.

    Pazár B, Gergely P Jr, Nagy ZB, Gombos T, Pozsonyi E, Rajczy K, Balogh Z, Sevcic K, Orbán I, Szodoray P, Poór G.

    Clin Exp Rheumatol. 2008 Nov-Dec;26(6):1146-52.PMID: 19210888 [PubMed - indexed for MEDLINE]Related articles

    13.

    Shared and distinct genetic variants in type 1 diabetes and celiac disease.

    Smyth DJ, Plagnol V, Walker NM, Cooper JD, Downes K, Yang JH, Howson JM, Stevens H, McManus R, Wijmenga C, Heap GA, Dubois PC, Clayton DG, Hunt KA, van Heel DA, Todd JA.

    N Engl J Med. 2008 Dec 25;359(26):2767-77. Epub 2008 Dec 10.PMID: 19073967 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    The protein tyrosine phosphatase N22 gene is associated with juvenile and adult idiopathic inflammatory myopathy independent of the HLA 8.1 haplotype in British Caucasian patients.

    Chinoy H, Platt H, Lamb JA, Betteridge Z, Gunawardena H, Fertig N, Varsani H, Davidson J, Oddis CV, McHugh NJ, Wedderburn LR, Ollier WE, Cooper RG; UK Adult Onset Myositis Immunogenetic Collaboration and the Juvenile Dermatomyositis Research Group.

    Arthritis Rheum. 2008 Oct;58(10):3247-54.PMID: 18821667 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: further support that PTPN22 is an autoimmunity gene.

    Hinks A, Barton A, John S, Bruce I, Hawkins C, Griffiths CE, Donn R, Thomson W, Silman A, Worthington J.

    Arthritis Rheum. 2005 Jun;52(6):1694-9.PMID: 15934099 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.

    Plenge RM, Seielstad M, Padyukov L, Lee AT, Remmers EF, Ding B, Liew A, Khalili H, Chandrasekaran A, Davies LR, Li W, Tan AK, Bonnard C, Ong RT, Thalamuthu A, Pettersson S, Liu C, Tian C, Chen WV, Carulli JP, Beckman EM, Altshuler D, Alfredsson L, Criswell LA, Amos CI, Seldin MF, Kastner DL, Klareskog L, Gregersen PK.

    N Engl J Med. 2007 Sep 20;357(12):1199-209. Epub 2007 Sep 5.PMID: 17804836 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Lymphoid tyrosine phosphatase (PTPN22/LYP) variant and Graves' disease in a Polish population: association and gene dose-dependent correlation with age of onset.

    Skórka A, Bednarczuk T, Bar-Andziak E, Nauman J, Ploski R.

    Clin Endocrinol (Oxf). 2005 Jun;62(6):679-82.PMID: 15943829 [PubMed - indexed for MEDLINE]Related articles

    18.

    Association of PTPN22 single nucleotide polymorphism with rheumatoid arthritis but not with allergic asthma.

    Majorczyk E, Jasek M, Płoski R, Wagner M, Kosior A, Pawlik A, Obojski A, Luszczek W, Nowak I, Wiśniewski A, Kuśnierczyk P.

    Eur J Hum Genet. 2007 Oct;15(10):1043-8. Epub 2007 Jun 20.PMID: 17579671 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking.

    Costenbader KH, Chang SC, De Vivo I, Plenge R, Karlson EW.

    Arthritis Res Ther. 2008;10(3):R52. Epub 2008 May 7.PMID: 18462498 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    A functional polymorphism (1858C/T) in the PTPN22 gene is linked and associated with type I diabetes in multiplex families.

    Onengut-Gumuscu S, Ewens KG, Spielman RS, Concannon P.

    Genes Immun. 2004 Dec;5(8):678-80.PMID: 15526003 [PubMed - indexed for MEDLINE]Related articles