PubMed

Peroxynitrite mediates retinal neurodegeneration by inhibiting nerve growth factor survival signaling in experimental and human diabetes.

Ali TK, Matragoon S, Pillai BA, Liou GI, El-Remessy AB.

Diabetes. 2008 Apr;57(4):889-98. Epub 2008 Feb 19.PMID: 18285558 [PubMed - indexed for MEDLINE]Related articlesFree article

Experimental diabetes causes breakdown of the blood-retina barrier by a mechanism involving tyrosine nitration and increases in expression of vascular endothelial growth factor and urokinase plasminogen activator receptor.

El-Remessy AB, Behzadian MA, Abou-Mohamed G, Franklin T, Caldwell RW, Caldwell RB.

Am J Pathol. 2003 Jun;162(6):1995-2004.PMID: 12759255 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinal p75 and bax overexpression is associated with retinal ganglion cells apoptosis in a rat model of glaucoma.

Coassin M, Lambiase A, Sposato V, Micera A, Bonini S, Aloe L.

Graefes Arch Clin Exp Ophthalmol. 2008 Dec;246(12):1743-9. Epub 2008 Aug 27.PMID: 18751719 [PubMed - indexed for MEDLINE]Related articles

Oxidative stress inactivates VEGF survival signaling in retinal endothelial cells via PI 3-kinase tyrosine nitration.

el-Remessy AB, Bartoli M, Platt DH, Fulton D, Caldwell RB.

J Cell Sci. 2005 Jan 1;118(Pt 1):243-52.PMID: 15615788 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes.

El-Remessy AB, Al-Shabrawey M, Khalifa Y, Tsai NT, Caldwell RB, Liou GI.

Am J Pathol. 2006 Jan;168(1):235-44.PMID: 16400026 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxynitrite transforms nerve growth factor into an apoptotic factor for motor neurons.

Pehar M, Vargas MR, Robinson KM, Cassina P, England P, Beckman JS, Alzari PM, Barbeito L.

Free Radic Biol Med. 2006 Dec 1;41(11):1632-44. Epub 2006 Aug 15.PMID: 17145551 [PubMed - indexed for MEDLINE]Related articles

Inhibition of nerve growth factor signaling by peroxynitrite.

Jonnala RR, Buccafusco JJ.

J Neurosci Res. 2001 Jan 1;63(1):27-34.PMID: 11169611 [PubMed - indexed for MEDLINE]Related articles

Effect of p75NTR on the regulation of naturally occurring cell death and retinal ganglion cell number in the mouse eye.

Harada C, Harada T, Nakamura K, Sakai Y, Tanaka K, Parada LF.

Dev Biol. 2006 Feb 1;290(1):57-65. Epub 2005 Dec 15.PMID: 16343477 [PubMed - indexed for MEDLINE]Related articles

Aldose reductase inhibitor ONO-2235 restores the alterations of bladder nerve growth factor and neurotrophin receptor p75 genetic expression in streptozotocin induced diabetic rats.

Tong YC, Cheng JT.

J Urol. 2007 Nov;178(5):2203-7. Epub 2007 Sep 17.PMID: 17870109 [PubMed - indexed for MEDLINE]Related articles

Inhibition of p75(NTR) in glia potentiates TrkA-mediated survival of injured retinal ganglion cells.

Lebrun-Julien F, Morquette B, Douillette A, Saragovi HU, Di Polo A.

Mol Cell Neurosci. 2009 Apr;40(4):410-20. Epub 2008 Dec 25.PMID: 19146958 [PubMed - indexed for MEDLINE]Related articles

Nerve growth factor supplementation reverses the impairment, induced by Type 1 diabetes, of hindlimb post-ischaemic recovery in mice.

Salis MB, Graiani G, Desortes E, Caldwell RB, Madeddu P, Emanueli C.

Diabetologia. 2004 Jun;47(6):1055-63. Epub 2004 Jun 8.PMID: 15184980 [PubMed - indexed for MEDLINE]Related articles

Nerve growth factor regulates substance P in adult sensory neurons through both TrkA and p75 receptors.

Skoff AM, Adler JE.

Exp Neurol. 2006 Feb;197(2):430-6. Epub 2005 Nov 21.PMID: 16300761 [PubMed - indexed for MEDLINE]Related articles

A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin-diabetic mice.

Drel VR, Pacher P, Vareniuk I, Pavlov I, Ilnytska O, Lyzogubov VV, Tibrewala J, Groves JT, Obrosova IG.

Eur J Pharmacol. 2007 Aug 13;569(1-2):48-58. Epub 2007 Jun 9.PMID: 17644085 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential activity of the nerve growth factor (NGF) antagonist PD90780 [7-(benzolylamino)-4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic acid] suggests altered NGF-p75NTR interactions in the presence of TrkA.

Colquhoun A, Lawrance GM, Shamovsky IL, Riopelle RJ, Ross GM.

J Pharmacol Exp Ther. 2004 Aug;310(2):505-11. Epub 2004 Mar 29.PMID: 15051797 [PubMed - indexed for MEDLINE]Related articlesFree article

A vitamin D(3) derivative (CB1093) induces nerve growth factor and prevents neurotrophic deficits in streptozotocin-diabetic rats.

Riaz S, Malcangio M, Miller M, Tomlinson DR.

Diabetologia. 1999 Nov;42(11):1308-13.PMID: 10550414 [PubMed - indexed for MEDLINE]Related articles

The p75 neurotrophin receptor enhances TrkA signalling by binding to Shc and augmenting its phosphorylation.

Epa WR, Markovska K, Barrett GL.

J Neurochem. 2004 Apr;89(2):344-53.PMID: 15056278 [PubMed - indexed for MEDLINE]Related articles

Diabetes reduces basal retinal insulin receptor signaling: reversal with systemic and local insulin.

Reiter CE, Wu X, Sandirasegarane L, Nakamura M, Gilbert KA, Singh RS, Fort PE, Antonetti DA, Gardner TW.

Diabetes. 2006 Apr;55(4):1148-56.PMID: 16567541 [PubMed - indexed for MEDLINE]Related articlesFree article

Stimulation of nerve growth factor expression in astrocytes by peroxynitrite.

Vargas MR, Pehar M, Cassina P, Estévez AG, Beckman JS, Barbeito L.

In Vivo. 2004 May-Jun;18(3):269-74.PMID: 15341182 [PubMed - indexed for MEDLINE]Related articles

Neurotrophic rationale in glaucoma: a TrkA agonist, but not NGF or a p75 antagonist, protects retinal ganglion cells in vivo.

Shi Z, Birman E, Saragovi HU.

Dev Neurobiol. 2007 Jun;67(7):884-94. Erratum in: Dev Neurobiol. 2007 Sep 15;67(11):1547-8. PMID: 17506493 [PubMed - indexed for MEDLINE]Related articles

Taurine counteracts oxidative stress and nerve growth factor deficit in early experimental diabetic neuropathy.

Obrosova IG, Fathallah L, Stevens MJ.

Exp Neurol. 2001 Nov;172(1):211-9.PMID: 11681853 [PubMed - indexed for MEDLINE]Related articles