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    Results: 1 to 20 of 405

    1.

    Recombinant human activated protein C: current insights into its mechanism of action.

    Levi M, van der Poll T.

    Crit Care. 2007;11 Suppl 5:S3. Review.PMID: 18269690 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Recombinant human activated protein C (Xigris).

    Levi M, De Jonge E, van der Poll T.

    Int J Clin Pract. 2002 Sep;56(7):542-5.PMID: 12296618 [PubMed - indexed for MEDLINE]Related articles

    3.

    Recombinant human activated protein C: a system modulator of vascular function for treatment of severe sepsis.

    Grinnell BW, Joyce D.

    Crit Care Med. 2001 Jul;29(7 Suppl):S53-60; discussion S60-1. Review.PMID: 11445735 [PubMed - indexed for MEDLINE]Related articles

    4.

    Soluble thrombomodulin, plasma-derived unactivated protein C, and recombinant human activated protein C in sepsis.

    Dhainaut JF, Yan SB, Cariou A, Mira JP.

    Crit Care Med. 2002 May;30(5 Suppl):S318-24. Review.PMID: 12004254 [PubMed - indexed for MEDLINE]Related articles

    5.

    Recombinant human activated protein C resets thrombin generation in patients with severe sepsis - a case control study.

    de Pont AC, Bakhtiari K, Hutten BA, de Jonge E, Vroom MB, Meijers JC, Büller HR, Levi M.

    Crit Care. 2005 Oct 5;9(5):R490-7. Epub 2005 Jul 21.PMID: 16277710 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Coagulopathy and the role of recombinant human activated protein C in sepsis and following polytrauma.

    Dahabreh Z, Dimitriou R, Chalidis B, Giannoudis PV.

    Expert Opin Drug Saf. 2006 Jan;5(1):67-82. Review. Erratum in: Expert Opin Drug Saf. 2006 Mar;5(2):345. PMID: 16370957 [PubMed - indexed for MEDLINE]Related articles

    7.

    [Activated protein C, coagulation, inflammation, and treatment of severe sepsis]

    van Deventer SJ, Pajkrt D.

    Ned Tijdschr Geneeskd. 2001 Mar 31;145(13):613-6. Review. Dutch. PMID: 11305209 [PubMed - indexed for MEDLINE]Related articles

    8.

    Activated protein C in sepsis: emerging insights regarding its mechanism of action and clinical effectiveness.

    Haley M, Cui X, Minneci PC, Deans KJ, Natanson C, Eichacker PQ.

    Curr Opin Infect Dis. 2004 Jun;17(3):205-11. Review.PMID: 15166822 [PubMed - indexed for MEDLINE]Related articles

    9.

    [Novel treatment for severe sepsis: recombinant human protein C (RHAPC)]

    Uszyiński W, Uszyński M, Lisiecki A.

    Ginekol Pol. 2005 Nov;76(11):913-20. Review. Polish. PMID: 16566369 [PubMed - indexed for MEDLINE]Related articles

    10.

    Recombinant human activated protein C (rhAPC; drotrecogin alfa [activated]) has minimal effect on markers of coagulation, fibrinolysis, and inflammation in acute human endotoxemia.

    Derhaschnig U, Reiter R, Knöbl P, Baumgartner M, Keen P, Jilma B.

    Blood. 2003 Sep 15;102(6):2093-8. Epub 2003 May 15.PMID: 12750166 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Protein C anticoagulant pathway and its role in controlling microvascular thrombosis and inflammation.

    Esmon CT.

    Crit Care Med. 2001 Jul;29(7 Suppl):S48-51; discussion 51-2. Review.PMID: 11445734 [PubMed - indexed for MEDLINE]Related articles

    12.

    Drotrecogin alfa activated (recombinant human activated protein C) in combination with heparin or melagatran: effects on prothrombin time and activated partial thromboplastin time.

    Koestenberger M, Cvirn G, Gallistl S, Muntean W.

    Blood Coagul Fibrinolysis. 2004 Oct;15(8):693-7.PMID: 15613925 [PubMed - indexed for MEDLINE]Related articles

    13.

    New and emerging therapies for sepsis.

    Healy DP.

    Ann Pharmacother. 2002 Apr;36(4):648-54. Review.PMID: 11918516 [PubMed - indexed for MEDLINE]Related articles

    14.

    Clinical and laboratory effects of recombinant human activated protein C in the treatment of a patient with sepsis-induced multiple organ failure.

    Brueckmann M, Wizenmann J, Hoffmann U, Seeger M, Bewig B.

    Thromb Res. 2003 Mar 15;109(5-6):259-63.PMID: 12818248 [PubMed - indexed for MEDLINE]Related articles

    15.

    Recombinant human activated protein C improves pulmonary function in ovine acute lung injury resulting from smoke inhalation and sepsis.

    Maybauer MO, Maybauer DM, Fraser JF, Traber LD, Westphal M, Enkhbaatar P, Cox RA, Huda R, Hawkins HK, Morita N, Murakami K, Mizutani A, Herndon DN, Traber DL.

    Crit Care Med. 2006 Sep;34(9):2432-8.PMID: 16810106 [PubMed - indexed for MEDLINE]Related articles

    16.

    The respective and combined anticoagulant effects of recombinant human activated protein C, melagatran and heparins using CAT.

    Cimenti C, Koestenberger M, Leschnik B, Haidl H, Muntean W.

    Thromb Res. 2007;119(3):361-7. Epub 2006 May 19.PMID: 16712904 [PubMed - indexed for MEDLINE]Related articles

    17.

    The coagulation cascade in sepsis.

    Wang L, Bastarache JA, Ware LB.

    Curr Pharm Des. 2008;14(19):1860-9. Review.PMID: 18691097 [PubMed - indexed for MEDLINE]Related articles

    18.

    Activated protein C in sepsis: a critical review.

    Levi M.

    Curr Opin Hematol. 2008 Sep;15(5):481-6. Review.PMID: 18695371 [PubMed - indexed for MEDLINE]Related articles

    19.

    Recombinant human activated protein C attenuates endotoxin-induced lung injury in awake sheep.

    Waerhaug K, Kuklin VN, Kirov MY, Sovershaev MA, Langbakk B, Ingebretsen OC, Ytrehus K, Bjertnaes LJ.

    Crit Care. 2008;12(4):R104. Epub 2008 Aug 15.PMID: 18702832 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Mechanism of action of drotrecogin alfa activated (rhAPC).

    Jilma B, Derhaschnig U.

    Thromb Haemost. 2004 May;91(5):1050. No abstract available. PMID: 15116270 [PubMed - indexed for MEDLINE]Related articles

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