PubMed

Selective activation of peroxisome proliferator-activated receptor (PPAR)alpha and PPAR gamma induces neoangiogenesis through a vascular endothelial growth factor-dependent mechanism.

Biscetti F, Gaetani E, Flex A, Aprahamian T, Hopkins T, Straface G, Pecorini G, Stigliano E, Smith RC, Angelini F, Castellot JJ Jr, Pola R.

Diabetes. 2008 May;57(5):1394-404. Epub 2008 Feb 11.PMID: 18268046 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparative analysis of the in vivo angiogenic properties of stable prostacyclin analogs: a possible role for peroxisome proliferator-activated receptors.

Pola R, Gaetani E, Flex A, Aprahamian TR, Bosch-Marcé M, Losordo DW, Smith RC, Pola P.

J Mol Cell Cardiol. 2004 Mar;36(3):363-70.PMID: 15010275 [PubMed - indexed for MEDLINE]Related articles

Platelet-activating factor enhances vascular endothelial growth factor-induced endothelial cell motility and neoangiogenesis in a murine matrigel model.

Montrucchio G, Lupia E, Battaglia E, Del Sorbo L, Boccellino M, Biancone L, Emanuelli G, Camussi G.

Arterioscler Thromb Vasc Biol. 2000 Jan;20(1):80-8.PMID: 10634803 [PubMed - indexed for MEDLINE]Related articlesFree article

PPAR-gamma agonists induce the expression of VEGF and its receptors in cultured cardiac myofibroblasts.

Chintalgattu V, Harris GS, Akula SM, Katwa LC.

Cardiovasc Res. 2007 Apr 1;74(1):140-50. Epub 2007 Jan 17.PMID: 17320065 [PubMed - indexed for MEDLINE]Related articlesFree article

Thromboxane A2 receptor signaling inhibits vascular endothelial growth factor-induced endothelial cell differentiation and migration.

Ashton AW, Ware JA.

Circ Res. 2004 Aug 20;95(4):372-9. Epub 2004 Jul 8.PMID: 15242977 [PubMed - indexed for MEDLINE]Related articlesFree article

Tumor angiogenesis suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via peroxisome proliferator-activated receptor gamma.

Tsuzuki T, Kawakami Y.

Carcinogenesis. 2008 Apr;29(4):797-806. Epub 2008 Jan 3.PMID: 18174233 [PubMed - indexed for MEDLINE]Related articlesFree article

PPAR gamma ligands, rosiglitazone and pioglitazone, inhibit bFGF- and VEGF-mediated angiogenesis.

Aljada A, O'Connor L, Fu YY, Mousa SA.

Angiogenesis. 2008;11(4):361-7. Epub 2008 Sep 23.PMID: 18810647 [PubMed - indexed for MEDLINE]Related articles

Water extract of Korean red ginseng stimulates angiogenesis by activating the PI3K/Akt-dependent ERK1/2 and eNOS pathways in human umbilical vein endothelial cells.

Kim YM, Namkoong S, Yun YG, Hong HD, Lee YC, Ha KS, Lee H, Kwon HJ, Kwon YG, Kim YM.

Biol Pharm Bull. 2007 Sep;30(9):1674-9.PMID: 17827719 [PubMed - indexed for MEDLINE]Related articlesFree article

PPAR-gamma activation inhibits angiogenesis by blocking ELR+CXC chemokine production in non-small cell lung cancer.

Keshamouni VG, Arenberg DA, Reddy RC, Newstead MJ, Anthwal S, Standiford TJ.

Neoplasia. 2005 Mar;7(3):294-301.PMID: 15799829 [PubMed - indexed for MEDLINE]Related articlesFree article

Aggretin, a snake venom-derived endothelial integrin alpha 2 beta 1 agonist, induces angiogenesis via expression of vascular endothelial growth factor.

Chung CH, Wu WB, Huang TF.

Blood. 2004 Mar 15;103(6):2105-13. Epub 2003 Nov 20.PMID: 14630793 [PubMed - indexed for MEDLINE]Related articlesFree article

Keratinocyte-derived vascular endothelial growth factor biosynthesis represents a pleiotropic side effect of peroxisome proliferator-activated receptor-gamma agonist troglitazone but not rosiglitazone and involves activation of p38 mitogen-activated protein kinase: implications for diabetes-impaired skin repair.

Schiefelbein D, Seitz O, Goren I, Dissmann JP, Schmidt H, Bachmann M, Sader R, Geisslinger G, Pfeilschifter J, Frank S.

Mol Pharmacol. 2008 Oct;74(4):952-63. Epub 2008 Jul 3.PMID: 18599600 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor alpha is crucial for iloprost-induced in vivo angiogenesis and vascular endothelial growth factor upregulation.

Biscetti F, Gaetani E, Flex A, Straface G, Pecorini G, Angelini F, Stigliano E, Aprahamian T, Smith RC, Castellot JJ, Pola R.

J Vasc Res. 2009;46(2):103-8. Epub 2008 Jul 10.PMID: 18617751 [PubMed - indexed for MEDLINE]Related articles

Activation of PPARbeta/delta induces endothelial cell proliferation and angiogenesis.

Piqueras L, Reynolds AR, Hodivala-Dilke KM, Alfranca A, Redondo JM, Hatae T, Tanabe T, Warner TD, Bishop-Bailey D.

Arterioscler Thromb Vasc Biol. 2007 Jan;27(1):63-9. Epub 2006 Oct 26.PMID: 17068288 [PubMed - indexed for MEDLINE]Related articlesFree article

Peroxisome proliferator-activated receptor alpha induces NADPH oxidase activity in macrophages, leading to the generation of LDL with PPAR-alpha activation properties.

Teissier E, Nohara A, Chinetti G, Paumelle R, Cariou B, Fruchart JC, Brandes RP, Shah A, Staels B.

Circ Res. 2004 Dec 10;95(12):1174-82. Epub 2004 Nov 11.PMID: 15539630 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth stimulation of COX-2-negative pancreatic cancer by a selective COX-2 inhibitor.

Eibl G, Takata Y, Boros LG, Liu J, Okada Y, Reber HA, Hines OJ.

Cancer Res. 2005 Feb 1;65(3):982-90.PMID: 15705899 [PubMed - indexed for MEDLINE]Related articlesFree article

Antiinflammatory effects of tetradecylthioacetic acid involve both peroxisome proliferator-activated receptor alpha-dependent and -independent pathways.

Dyrøy E, Yndestad A, Ueland T, Halvorsen B, Damås JK, Aukrust P, Berge RK.

Arterioscler Thromb Vasc Biol. 2005 Jul;25(7):1364-9. Epub 2005 May 26.PMID: 15920037 [PubMed - indexed for MEDLINE]Related articlesFree article

hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists.

Li Y, Wen X, Spataro BC, Hu K, Dai C, Liu Y.

J Am Soc Nephrol. 2006 Jan;17(1):54-65. Epub 2005 Nov 16.PMID: 16291834 [PubMed - indexed for MEDLINE]Related articlesFree article

Rosiglitazone facilitates angiogenic progenitor cell differentiation toward endothelial lineage: a new paradigm in glitazone pleiotropy.

Wang CH, Ciliberti N, Li SH, Szmitko PE, Weisel RD, Fedak PW, Al-Omran M, Cherng WJ, Li RK, Stanford WL, Verma S.

Circulation. 2004 Mar 23;109(11):1392-400. Epub 2004 Mar 1.PMID: 14993120 [PubMed - indexed for MEDLINE]Related articlesFree article

Doxazosin inhibits human vascular endothelial cell adhesion, migration, and invasion.

Keledjian K, Garrison JB, Kyprianou N.

J Cell Biochem. 2005 Feb 1;94(2):374-88.PMID: 15526277 [PubMed - indexed for MEDLINE]Related articles

Isoprostanes inhibit vascular endothelial growth factor-induced endothelial cell migration, tube formation, and cardiac vessel sprouting in vitro, as well as angiogenesis in vivo via activation of the thromboxane A(2) receptor: a potential link between oxidative stress and impaired angiogenesis.

Benndorf RA, Schwedhelm E, Gnann A, Taheri R, Kom G, Didié M, Steenpass A, Ergün S, Böger RH.

Circ Res. 2008 Oct 24;103(9):1037-46. Epub 2008 Sep 18.PMID: 18802021 [PubMed - indexed for MEDLINE]Related articlesFree article