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    Results: 1 to 20 of 447

    1.

    Regulatory T-cells protect from type 1 diabetes after induction by coxsackievirus infection in the context of transforming growth factor-beta.

    Richer MJ, Straka N, Fang D, Shanina I, Horwitz MS.

    Diabetes. 2008 May;57(5):1302-11. Epub 2008 Feb 11.PMID: 18268045 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice.

    Filippi CM, Estes EA, Oldham JE, von Herrath MG.

    J Clin Invest. 2009 Jun;119(6):1515-23. doi: 10.1172/JCI38503. Epub 2009 May 26.PMID: 19478458 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Retroviral delivery of GAD-IgG fusion construct induces tolerance and modulates diabetes: a role for CD4+ regulatory T cells and TGF-beta?

    Song L, Wang J, Wang R, Yu M, Sun Y, Han G, Li Y, Qian J, Scott DW, Kang Y, Soukhareva N, Shen B.

    Gene Ther. 2004 Oct;11(20):1487-96.PMID: 15343360 [PubMed - indexed for MEDLINE]Related articles

    4.

    Adaptive TGF-beta-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment.

    You S, Leforban B, Garcia C, Bach JF, Bluestone JA, Chatenoud L.

    Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6335-40. Epub 2007 Mar 26.PMID: 17389382 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    A sudden decline in active membrane-bound TGF-beta impairs both T regulatory cell function and protection against autoimmune diabetes.

    Gregg RK, Jain R, Schoenleber SJ, Divekar R, Bell JJ, Lee HH, Yu P, Zaghouani H.

    J Immunol. 2004 Dec 15;173(12):7308-16.PMID: 15585854 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Presented antigen from damaged pancreatic beta cells activates autoreactive T cells in virus-mediated autoimmune diabetes.

    Horwitz MS, Ilic A, Fine C, Rodriguez E, Sarvetnick N.

    J Clin Invest. 2002 Jan;109(1):79-87.PMID: 11781353 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Requirements for viral-mediated autoimmune diabetes: beta-cell damage and immune infiltration.

    Horwitz MS, Fine C, Ilic A, Sarvetnick N.

    J Autoimmun. 2001 May;16(3):211-7.PMID: 11334485 [PubMed - indexed for MEDLINE]Related articles

    8.

    Regulatory T cells prevent transfer of type 1 diabetes in NOD mice only when their antigen is present in vivo.

    Tonkin DR, He J, Barbour G, Haskins K.

    J Immunol. 2008 Oct 1;181(7):4516-22.PMID: 18802054 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Regulatory T cells enter the pancreas during suppression of type 1 diabetes and inhibit effector T cells and macrophages in a TGF-beta-dependent manner.

    Tonkin DR, Haskins K.

    Eur J Immunol. 2009 May;39(5):1313-22.PMID: 19404982 [PubMed - indexed for MEDLINE]Related articles

    10.

    Treatment with granulocyte colony-stimulating factor prevents diabetes in NOD mice by recruiting plasmacytoid dendritic cells and functional CD4(+)CD25(+) regulatory T-cells.

    Kared H, Masson A, Adle-Biassette H, Bach JF, Chatenoud L, Zavala F.

    Diabetes. 2005 Jan;54(1):78-84.PMID: 15616013 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells.

    Gaudreau S, Guindi C, Ménard M, Besin G, Dupuis G, Amrani A.

    J Immunol. 2007 Sep 15;179(6):3638-47.PMID: 17785799 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Essential roles of TGF-beta in anti-CD3 antibody therapy: reversal of diabetes in nonobese diabetic mice independent of Foxp3+CD4+ regulatory T cells.

    Chen G, Han G, Wang J, Wang R, Xu R, Shen B, Qian J, Li Y.

    J Leukoc Biol. 2008 Feb;83(2):280-7. Epub 2007 Nov 20.PMID: 18029395 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Coxsackieviral-mediated diabetes: induction requires antigen-presenting cells and is accompanied by phagocytosis of beta cells.

    Horwitz MS, Ilic A, Fine C, Balasa B, Sarvetnick N.

    Clin Immunol. 2004 Feb;110(2):134-44.PMID: 15003810 [PubMed - indexed for MEDLINE]Related articles

    14.

    TGF-beta signaling is required for the function of insulin-reactive T regulatory cells.

    Du W, Wong FS, Li MO, Peng J, Qi H, Flavell RA, Sherwin R, Wen L.

    J Clin Invest. 2006 May;116(5):1360-70. Erratum in: J Clin Invest. 2006 Jun;116(6):1738. PMID: 16670772 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Systemic transforming growth factor-beta1 gene therapy induces Foxp3+ regulatory cells, restores self-tolerance, and facilitates regeneration of beta cell function in overtly diabetic nonobese diabetic mice.

    Luo X, Yang H, Kim IS, Saint-Hilaire F, Thomas DA, De BP, Ozkaynak E, Muthukumar T, Hancock WW, Crystal RG, Suthanthiran M.

    Transplantation. 2005 May 15;79(9):1091-6.PMID: 15880049 [PubMed - indexed for MEDLINE]Related articles

    16.

    CD28/CD154 blockade prevents autoimmune diabetes by inducing nondeletional tolerance after effector t-cell inhibition and regulatory T-cell expansion.

    Rigby MR, Trexler AM, Pearson TC, Larsen CP.

    Diabetes. 2008 Oct;57(10):2672-83. Epub 2008 May 20.PMID: 18492787 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Can childhood viral infection protect from type 1 diabetes?

    Strom TB.

    J Clin Invest. 2009 Jun;119(6):1458-61.PMID: 19504721 [PubMed - indexed for MEDLINE]Related articles

    18.

    Diabetogenic potential of human pathogens uncovered in experimentally permissive beta-cells.

    Flodström M, Tsai D, Fine C, Maday A, Sarvetnick N.

    Diabetes. 2003 Aug;52(8):2025-34.PMID: 12882919 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    CD4+ CD25+ Foxp3+ regulatory T cells protect against T cell-mediated fulminant hepatitis in a TGF-beta-dependent manner in mice.

    Wei HX, Chuang YH, Li B, Wei H, Sun R, Moritoki Y, Gershwin ME, Lian ZX, Tian Z.

    J Immunol. 2008 Nov 15;181(10):7221-9.PMID: 18981144 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Schistosoma mansoni egg antigens induce Treg that participate in diabetes prevention in NOD mice.

    Zaccone P, Burton O, Miller N, Jones FM, Dunne DW, Cooke A.

    Eur J Immunol. 2009 Apr;39(4):1098-107.PMID: 19291704 [PubMed - indexed for MEDLINE]Related articles

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