PubMed

Association of NOS1AP genetic variants with QT interval duration in families from the Diabetes Heart Study.

Lehtinen AB, Newton-Cheh C, Ziegler JT, Langefeld CD, Freedman BI, Daniel KR, Herrington DM, Bowden DW.

Diabetes. 2008 Apr;57(4):1108-14. Epub 2008 Jan 30.PMID: 18235038 [PubMed - indexed for MEDLINE]Related articlesFree article

Common NOS1AP variants are associated with a prolonged QTc interval in the Rotterdam Study.

Aarnoudse AJ, Newton-Cheh C, de Bakker PI, Straus SM, Kors JA, Hofman A, Uitterlinden AG, Witteman JC, Stricker BH.

Circulation. 2007 Jul 3;116(1):10-6. Epub 2007 Jun 18.PMID: 17576865 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of a common variant at the NOS1AP locus strongly associated to QT-interval duration.

Eijgelsheim M, Aarnoudse AL, Rivadeneira F, Kors JA, Witteman JC, Hofman A, van Duijn CM, Uitterlinden AG, Stricker BH.

Hum Mol Genet. 2009 Jan 15;18(2):347-57. Epub 2008 Oct 16.PMID: 18927126 [PubMed - indexed for MEDLINE]Related articles

Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations.

Kao WH, Arking DE, Post W, Rea TD, Sotoodehnia N, Prineas RJ, Bishe B, Doan BQ, Boerwinkle E, Psaty BM, Tomaselli GF, Coresh J, Siscovick DS, Marbán E, Spooner PM, Burke GL, Chakravarti A.

Circulation. 2009 Feb 24;119(7):940-51. Epub 2009 Feb 9.PMID: 19204306 [PubMed - indexed for MEDLINE]Related articles

Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population.

Arking DE, Khera A, Xing C, Kao WH, Post W, Boerwinkle E, Chakravarti A.

PLoS One. 2009;4(1):e4333. Epub 2009 Jan 30.PMID: 19180230 [PubMed - indexed for MEDLINE]Related articlesFree article

Associations between genetic variants in the NOS1AP (CAPON) gene and cardiac repolarization in the old order Amish.

Post W, Shen H, Damcott C, Arking DE, Kao WH, Sack PA, Ryan KA, Chakravarti A, Mitchell BD, Shuldiner AR.

Hum Hered. 2007;64(4):214-9. Epub 2007 Jun 12.PMID: 17565224 [PubMed - indexed for MEDLINE]Related articlesFree article

Common candidate gene variants are associated with QT interval duration in the general population.

Marjamaa A, Newton-Cheh C, Porthan K, Reunanen A, Lahermo P, Väänänen H, Jula A, Karanko H, Swan H, Toivonen L, Nieminen MS, Viitasalo M, Peltonen L, Oikarinen L, Palotie A, Kontula K, Salomaa V.

J Intern Med. 2009 Apr;265(4):448-58. Epub 2009 Oct 25.PMID: 19019189 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship between genetic variants in myocardial sodium and potassium channel genes and QT interval duration in diabetics: the Diabetes Heart Study.

Lehtinen AB, Daniel KR, Shah SA, Nelson MR, Ziegler JT, Freedman BI, Carr JJ, Herrington DM, Langefeld CD, Bowden DW.

Ann Noninvasive Electrocardiol. 2009 Jan;14(1):72-9.PMID: 19149796 [PubMed - indexed for MEDLINE]Related articles

Common variation in NOS1AP and KCNH2 genes and QT interval duration in young adults. The Cardiovascular Risk in Young Finns Study.

Raitakari OT, Blom-Nyholm J, Koskinen TA, Kähönen M, Viikari JS, Lehtimäki T.

Ann Med. 2009;41(2):144-51.PMID: 18785031 [PubMed - indexed for MEDLINE]Related articles

Gender and effects of a common genetic variant in the NOS1 regulator NOS1AP on cardiac repolarization in 3761 individuals from two independent populations.

Tobin MD, Kähönen M, Braund P, Nieminen T, Hajat C, Tomaszewski M, Viik J, Lehtinen R, Ng GA, Macfarlane PW, Burton PR, Lehtimäki T, Samani NJ.

Int J Epidemiol. 2008 Oct;37(5):1132-41. Epub 2008 May 29.PMID: 18511491 [PubMed - indexed for MEDLINE]Related articlesFree article

Calcium channel blockers, NOS1AP, and heart-rate-corrected QT prolongation.

van Noord C, Aarnoudse AJ, Eijgelsheim M, Sturkenboom MC, Straus SM, Hofman A, Kors JA, Newton-Cheh C, Witteman JC, Stricker BH.

Pharmacogenet Genomics. 2009 Apr;19(4):260-6.PMID: 19247217 [PubMed - indexed for MEDLINE]Related articles

Association of the distal region of the ectonucleotide pyrophosphatase/phosphodiesterase 1 gene with type 2 diabetes in an African-American population enriched for nephropathy.

Keene KL, Mychaleckyj JC, Smith SG, Leak TS, Perlegas PS, Langefeld CD, Freedman BI, Rich SS, Bowden DW, Sale MM.

Diabetes. 2008 Apr;57(4):1057-62. Epub 2008 Jan 9.PMID: 18184924 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits.

Andreasen CH, Mogensen MS, Borch-Johnsen K, Sandbaek A, Lauritzen T, Almind K, Hansen L, Jørgensen T, Pedersen O, Hansen T.

BMC Med Genet. 2008 Dec 26;9:118.PMID: 19111066 [PubMed - indexed for MEDLINE]Related articlesFree article

NOS1AP is a genetic modifier of the long-QT syndrome.

Crotti L, Monti MC, Insolia R, Peljto A, Goosen A, Brink PA, Greenberg DA, Schwartz PJ, George AL Jr.

Circulation. 2009 Oct 27;120(17):1657-63. Epub 2009 Oct 12.PMID: 19822806 [PubMed - indexed for MEDLINE]Related articles

Association of polymorphisms at the ADIPOR1 regulatory region with type 2 diabetes and body mass index in a Brazilian population with European or African ancestry.

Yeh E, Kimura L, Errera FI, Angeli CB, Mingroni-Netto RC, Silva ME, Canani LH, Passos-Bueno MR.

Braz J Med Biol Res. 2008 Jun;41(6):468-72.PMID: 18622492 [PubMed - indexed for MEDLINE]Related articlesFree article

Association of GCKR rs780094, alone or in combination with GCK rs1799884, with type 2 diabetes and related traits in a Han Chinese population.

Qi Q, Wu Y, Li H, Loos RJ, Hu FB, Sun L, Lu L, Pan A, Liu C, Wu H, Chen L, Yu Z, Lin X.

Diabetologia. 2009 May;52(5):834-43. Epub 2009 Feb 25.PMID: 19241058 [PubMed - indexed for MEDLINE]Related articles

Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study.

Palmer ND, Goodarzi MO, Langefeld CD, Ziegler J, Norris JM, Haffner SM, Bryer-Ash M, Bergman RN, Wagenknecht LE, Taylor KD, Rotter JI, Bowden DW.

Diabetes. 2008 Apr;57(4):1093-100. Epub 2008 Feb 5.PMID: 18252897 [PubMed - indexed for MEDLINE]Related articlesFree article

Aryl hydrocarbon receptor nuclear translocator (ARNT) gene as a positional and functional candidate for type 2 diabetes and prediabetic intermediate traits: Mutation detection, case-control studies, and gene expression analysis.

Das SK, Sharma NK, Chu WS, Wang H, Elbein SC.

BMC Med Genet. 2008 Mar 17;9:16.PMID: 18366646 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical correlates and heritability of QT interval duration in blacks: the Jackson Heart Study.

Akylbekova EL, Crow RS, Johnson WD, Buxbaum SG, Njemanze S, Fox E, Sarpong DF, Taylor HA, Newton-Cheh C.

Circ Arrhythm Electrophysiol. 2009 Aug;2(4):427-32. Epub 2009 May 27.PMID: 19808499 [PubMed - indexed for MEDLINE]Related articles

Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies.

Lewis JP, Palmer ND, Hicks PJ, Sale MM, Langefeld CD, Freedman BI, Divers J, Bowden DW.

Diabetes. 2008 Aug;57(8):2220-5. Epub 2008 Apr 28.PMID: 18443202 [PubMed - indexed for MEDLINE]Related articlesFree article