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    Results: 1 to 20 of 414

    1.

    Cartilage preservation by inhibition of Janus kinase 3 in two rodent models of rheumatoid arthritis.

    Milici AJ, Kudlacz EM, Audoly L, Zwillich S, Changelian P.

    Arthritis Res Ther. 2008;10(1):R14. Epub 2008 Jan 30.

    PMID:
    18234077
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: potential proinflammatory mechanisms.

    Thiel MJ, Schaefer CJ, Lesch ME, Mobley JL, Dudley DT, Tecle H, Barrett SD, Schrier DJ, Flory CM.

    Arthritis Rheum. 2007 Oct;56(10):3347-57.

    PMID:
    17907188
    [PubMed - indexed for MEDLINE]
    Free Article
    3.

    Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis.

    Young DA, Hegen M, Ma HL, Whitters MJ, Albert LM, Lowe L, Senices M, Wu PW, Sibley B, Leathurby Y, Brown TP, Nickerson-Nutter C, Keith JC Jr, Collins M.

    Arthritis Rheum. 2007 Apr;56(4):1152-63.

    PMID:
    17393408
    [PubMed - indexed for MEDLINE]
    Free Article
    4.

    Selective inhibition of JAK1 and JAK2 is efficacious in rodent models of arthritis: preclinical characterization of INCB028050.

    Fridman JS, Scherle PA, Collins R, Burn TC, Li Y, Li J, Covington MB, Thomas B, Collier P, Favata MF, Wen X, Shi J, McGee R, Haley PJ, Shepard S, Rodgers JD, Yeleswaram S, Hollis G, Newton RC, Metcalf B, Friedman SM, Vaddi K.

    J Immunol. 2010 May 1;184(9):5298-307. Epub 2010 Apr 2.

    PMID:
    20363976
    [PubMed - indexed for MEDLINE]
    Free Article
    5.

    Inflammatory cytokine levels in paw tissues during development of rat collagen-induced arthritis: effect of FK506, an inhibitor of T cell activation.

    Magari K, Miyata S, Ohkubo Y, Mutoh S.

    Inflamm Res. 2004 Sep;53(9):469-74.

    PMID:
    15551000
    [PubMed - indexed for MEDLINE]
    6.

    Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).

    Ghoreschi K, Jesson MI, Li X, Lee JL, Ghosh S, Alsup JW, Warner JD, Tanaka M, Steward-Tharp SM, Gadina M, Thomas CJ, Minnerly JC, Storer CE, LaBranche TP, Radi ZA, Dowty ME, Head RD, Meyer DM, Kishore N, O'Shea JJ.

    J Immunol. 2011 Apr 1;186(7):4234-43. Epub 2011 Mar 7.

    PMID:
    21383241
    [PubMed - indexed for MEDLINE]
    7.

    Immunosuppressive activity of 15-deoxyspergualin (15-DOS) on various models of rheumatoid arthritis.

    Schorlemmer HU, Bartlett RR, Schleyerbach R, Seiler FR.

    Drugs Exp Clin Res. 1991;17(10-11):471-84.

    PMID:
    1841036
    [PubMed - indexed for MEDLINE]
    8.

    Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis.

    Jüngel A, Ospelt C, Lesch M, Thiel M, Sunyer T, Schorr O, Michel BA, Gay RE, Kolling C, Flory C, Gay S, Neidhart M.

    Ann Rheum Dis. 2010 May;69(5):898-902. Epub 2009 Jun 3.

    PMID:
    19497915
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    9.

    Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis: comparison of efficacy in animal models with human clinical data.

    Bendele A, McAbee T, Sennello G, Frazier J, Chlipala E, McCabe D.

    Arthritis Rheum. 1999 Mar;42(3):498-506.

    PMID:
    10088773
    [PubMed - indexed for MEDLINE]
    Free Article
    10.

    Glycogen synthase kinase-3beta inhibition attenuates the degree of arthritis caused by type II collagen in the mouse.

    Cuzzocrea S, Mazzon E, Di Paola R, Muià C, Crisafulli C, Dugo L, Collin M, Britti D, Caputi AP, Thiemermann C.

    Clin Immunol. 2006 Jul;120(1):57-67. Epub 2006 May 2.

    PMID:
    16631408
    [PubMed - indexed for MEDLINE]
    11.

    T-614, a novel immunomodulator, attenuates joint inflammation and articular damage in collagen-induced arthritis.

    Du F, Lü LJ, Fu Q, Dai M, Teng JL, Fan W, Chen SL, Ye P, Shen N, Huang XF, Qian J, Bao CD.

    Arthritis Res Ther. 2008;10(6):R136. Epub 2008 Nov 19.

    PMID:
    19019215
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    12.

    Efficacy of daily compared to intermittent administration of IL-1Ra for protection against bone and cartilage destruction in collagen-challenged mice.

    Inoue K, Masuko-Hongo K, Okamoto M, Nishioka K.

    Clin Exp Rheumatol. 2003 Jan-Feb;21(1):33-9.

    PMID:
    12673887
    [PubMed - indexed for MEDLINE]
    13.

    Synergistic protection against cartilage destruction by low dose prednisolone and interleukin-10 in established murine collagen arthritis.

    Joosten LA, Helsen MM, Saxne T, Heinegård D, van de Putte LB, van den Berg WB.

    Inflamm Res. 1999 Jan;48(1):48-55.

    PMID:
    9987683
    [PubMed - indexed for MEDLINE]
    14.

    Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis.

    Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T, Weissleder R, Mahmood U, Healy AM, Jaffee B.

    Arthritis Rheum. 2007 Jan;56(1):117-28.

    PMID:
    17195214
    [PubMed - indexed for MEDLINE]
    Free Article
    15.

    Interleukin-10 inhibition of the progression of established collagen-induced arthritis.

    Walmsley M, Katsikis PD, Abney E, Parry S, Williams RO, Maini RN, Feldmann M.

    Arthritis Rheum. 1996 Mar;39(3):495-503.

    PMID:
    8607899
    [PubMed - indexed for MEDLINE]
    16.

    A highly selective inhibitor of I kappa B kinase, BMS-345541, blocks both joint inflammation and destruction in collagen-induced arthritis in mice.

    McIntyre KW, Shuster DJ, Gillooly KM, Dambach DM, Pattoli MA, Lu P, Zhou XD, Qiu Y, Zusi FC, Burke JR.

    Arthritis Rheum. 2003 Sep;48(9):2652-9.

    PMID:
    13130486
    [PubMed - indexed for MEDLINE]
    Free Article
    17.

    Methionine aminopeptidase-2 blockade reduces chronic collagen-induced arthritis: potential role for angiogenesis inhibition.

    Bainbridge J, Madden L, Essex D, Binks M, Malhotra R, Paleolog EM.

    Arthritis Res Ther. 2007;9(6):R127.

    PMID:
    18072970
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    18.

    Joint cytokine quantification in two rodent arthritis models: kinetics of expression, correlation of mRNA and protein levels and response to prednisolone treatment.

    Rioja I, Bush KA, Buckton JB, Dickson MC, Life PF.

    Clin Exp Immunol. 2004 Jul;137(1):65-73.

    PMID:
    15196245
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    19.

    Amelioration of collagen-induced arthritis in mice by a novel phosphodiesterase 7 and 4 dual inhibitor, YM-393059.

    Yamamoto S, Sugahara S, Ikeda K, Shimizu Y.

    Eur J Pharmacol. 2007 Mar 22;559(2-3):219-26. Epub 2006 Dec 12.

    PMID:
    17250824
    [PubMed - indexed for MEDLINE]
    20.

    IL-1β and TNFα-initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis.

    Mori T, Miyamoto T, Yoshida H, Asakawa M, Kawasumi M, Kobayashi T, Morioka H, Chiba K, Toyama Y, Yoshimura A.

    Int Immunol. 2011 Nov;23(11):701-12. Epub 2011 Sep 21.

    PMID:
    21937456
    [PubMed - indexed for MEDLINE]

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