PubMed

Multiple independent origins of a protease inhibitor resistance mutation in salvage therapy patients.

Kapoor A, Shapiro B, Shafer RW, Shulman N, Rhee SY, Delwart EL.

Retrovirology. 2008 Jan 25;5:7.PMID: 18221530 [PubMed - indexed for MEDLINE]Related articlesFree article

Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients.

Verheyen J, Litau E, Sing T, Däumer M, Balduin M, Oette M, Fätkenheuer G, Rockstroh JK, Schuldenzucker U, Hoffmann D, Pfister H, Kaiser R.

Antivir Ther. 2006;11(7):879-87.PMID: 17302250 [PubMed - indexed for MEDLINE]Related articles

Evolution of primary protease inhibitor resistance mutations during protease inhibitor salvage therapy.

Kantor R, Fessel WJ, Zolopa AR, Israelski D, Shulman N, Montoya JG, Harbour M, Schapiro JM, Shafer RW.

Antimicrob Agents Chemother. 2002 Apr;46(4):1086-92.PMID: 11897594 [PubMed - indexed for MEDLINE]Related articlesFree article

Phenotypic cross-resistance to nelfinavir: the role of prior antiretroviral therapy and the number of mutations in the protease gene.

Dronda F, Casado JL, Moreno S, Hertogs K, García-Arata I, Antela A, Pérez-Elías MJ, Ruiz L, Larder B; NELSANE Study.

AIDS Res Hum Retroviruses. 2001 Feb 10;17(3):211-5.PMID: 11177403 [PubMed - indexed for MEDLINE]Related articles

Multiple, linked human immunodeficiency virus type 1 drug resistance mutations in treatment-experienced patients are missed by standard genotype analysis.

Palmer S, Kearney M, Maldarelli F, Halvas EK, Bixby CJ, Bazmi H, Rock D, Falloon J, Davey RT Jr, Dewar RL, Metcalf JA, Hammer S, Mellors JW, Coffin JM.

J Clin Microbiol. 2005 Jan;43(1):406-13.PMID: 15635002 [PubMed - indexed for MEDLINE]Related articlesFree article

Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sites.

Zhang YM, Imamichi H, Imamichi T, Lane HC, Falloon J, Vasudevachari MB, Salzman NP.

J Virol. 1997 Sep;71(9):6662-70.PMID: 9261388 [PubMed - indexed for MEDLINE]Related articlesFree article

Interference between D30N and L90M in selection and development of protease inhibitor-resistant human immunodeficiency virus type 1.

Sugiura W, Matsuda Z, Yokomaku Y, Hertogs K, Larder B, Oishi T, Okano A, Shiino T, Tatsumi M, Matsuda M, Abumi H, Takata N, Shirahata S, Yamada K, Yoshikura H, Nagai Y.

Antimicrob Agents Chemother. 2002 Mar;46(3):708-15.PMID: 11850252 [PubMed - indexed for MEDLINE]Related articlesFree article

Evolution and predictors of HIV type-1 drug resistance in patients failing combination antiretroviral therapy in Italy.

Di Giambenedetto S, Zazzi M, Corsi P, Gonnelli A, Di Pietro M, Giacometti A, Almi P, Trezzi M, Boeri E, Gianotti N, Menzo S, Del Gobbo R, Francisci D, Nerli A, Galli L, De Luca A; Antiretroviral Resistance Cohort Analysis Study Group.

Antivir Ther. 2009;14(3):359-69.PMID: 19474470 [PubMed - indexed for MEDLINE]Related articles

Sequencing-based detection of low-frequency human immunodeficiency virus type 1 drug-resistant mutants by an RNA/DNA heteroduplex generator-tracking assay.

Kapoor A, Jones M, Shafer RW, Rhee SY, Kazanjian P, Delwart EL.

J Virol. 2004 Jul;78(13):7112-23.PMID: 15194787 [PubMed - indexed for MEDLINE]Related articlesFree article

N88D facilitates the co-occurrence of D30N and L90M and the development of multidrug resistance in HIV type 1 protease following nelfinavir treatment failure.

Mitsuya Y, Winters MA, Fessel WJ, Rhee SY, Hurley L, Horberg M, Schiffer CA, Zolopa AR, Shafer RW.

AIDS Res Hum Retroviruses. 2006 Dec;22(12):1300-5.PMID: 17209774 [PubMed - indexed for MEDLINE]Related articlesFree article

Population genetic analysis of the protease locus of human immunodeficiency virus type 1 quasispecies undergoing drug selection, using a denaturing gradient-heteroduplex tracking assay.

Doukhan L, Delwart E.

J Virol. 2001 Jul;75(14):6729-36.PMID: 11413343 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure.

Dumans AT, Barreto CC, Santos AF, Arruda M, Sousa TM, Machado ES, Sabino EC, Brindeiro RM, Tanuri A, Duarte AJ, Soares MA.

Infect Genet Evol. 2009 Jan;9(1):62-70. Epub 2008 Oct 17.PMID: 18992847 [PubMed - indexed for MEDLINE]Related articles

Mutational patterns and correlated amino acid substitutions in the HIV-1 protease after virological failure to nelfinavir- and lopinavir/ritonavir-based treatments.

Garriga C, Pérez-Elías MJ, Delgado R, Ruiz L, Nájera R, Pumarola T, Alonso-Socas Mdel M, García-Bujalance S, Menéndez-Arias L; Spanish Group for the Study of Antiretroviral Drug Resistance.

J Med Virol. 2007 Nov;79(11):1617-28.PMID: 17854027 [PubMed - indexed for MEDLINE]Related articles

Role of HIV-1 minority populations on resistance mutational pattern evolution and susceptibility to protease inhibitors.

Roquebert B, Malet I, Wirden M, Tubiana R, Valantin MA, Simon A, Katlama C, Peytavin G, Calvez V, Marcelin AG.

AIDS. 2006 Jan 9;20(2):287-9.PMID: 16511425 [PubMed - indexed for MEDLINE]Related articles

Emergence of protease inhibitor resistance mutations in human immunodeficiency virus type 1 isolates from patients and rapid screening procedure for their detection.

Vasudevachari MB, Zhang YM, Imamichi H, Imamichi T, Falloon J, Salzman NP.

Antimicrob Agents Chemother. 1996 Nov;40(11):2535-41.PMID: 8913459 [PubMed - indexed for MEDLINE]Related articlesFree article

Evolution of the HIV-1 protease region in heavily pretreated HIV-1 infected patients receiving Atazanavir.

Vergani B, Cicero ML, Vigano' O, Sirianni F, Ferramosca S, Vitiello P, Di Vincenzo P, Pia De Pasquale M, Galli M, Rusconi S.

J Clin Virol. 2008 Feb;41(2):154-9. Epub 2007 Nov 19.PMID: 18024202 [PubMed - indexed for MEDLINE]Related articles

Emergence of antiretroviral drug resistance in therapy-naive HIV infected patients in Hungary.

Juhász E, Ghidán A, Kemény B, Nagy K.

Acta Microbiol Immunol Hung. 2008 Dec;55(4):383-94.PMID: 19130746 [PubMed - indexed for MEDLINE]Related articles

Changes in human immunodeficiency virus type 1 Gag at positions L449 and P453 are linked to I50V protease mutants in vivo and cause reduction of sensitivity to amprenavir and improved viral fitness in vitro.

Maguire MF, Guinea R, Griffin P, Macmanus S, Elston RC, Wolfram J, Richards N, Hanlon MH, Porter DJ, Wrin T, Parkin N, Tisdale M, Furfine E, Petropoulos C, Snowden BW, Kleim JP.

J Virol. 2002 Aug;76(15):7398-406.PMID: 12097552 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalence of HIV protease mutations on failure of nelfinavir-containing HAART: a retrospective analysis of four clinical studies and two observational cohorts.

Clotet B, Ruiz L, Martinez-Picado J, Negredo E, Hill A, Popescu M.

HIV Clin Trials. 2002 Jul-Aug;3(4):316-23.PMID: 12187506 [PubMed - indexed for MEDLINE]Related articlesFree article

Changes in human immunodeficiency virus type 1 populations after treatment interruption in patients failing antiretroviral therapy.

Hance AJ, Lemiale V, Izopet J, Lecossier D, Joly V, Massip P, Mammano F, Descamps D, Brun-Vézinet F, Clavel F.

J Virol. 2001 Jul;75(14):6410-7.PMID: 11413308 [PubMed - indexed for MEDLINE]Related articlesFree article