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Polyamine depletion induces G1 and S phase arrest in human retinoblastoma Y79 cells.

Ueda A, Araie M, Kubota S.

Cancer Cell Int. 2008 Jan 21;8:2.PMID: 18208615 [PubMed]Related articlesFree article

Key role for p27Kip1, retinoblastoma protein Rb, and MYCN in polyamine inhibitor-induced G1 cell cycle arrest in MYCN-amplified human neuroblastoma cells.

Wallick CJ, Gamper I, Thorne M, Feith DJ, Takasaki KY, Wilson SM, Seki JA, Pegg AE, Byus CV, Bachmann AS.

Oncogene. 2005 Aug 25;24(36):5606-18.PMID: 16007177 [PubMed - indexed for MEDLINE]Related articles

p53 independent G(1) arrest induced by DL-alpha-difluoromethylornithine.

Nemoto T, Kamei S, Seyama Y, Kubota S.

Biochem Biophys Res Commun. 2001 Jan 26;280(3):848-54.PMID: 11162600 [PubMed - indexed for MEDLINE]Related articles

Ornithine decarboxylase inhibition by alpha-difluoromethylornithine activates opposing signaling pathways via phosphorylation of both Akt/protein kinase B and p27Kip1 in neuroblastoma.

Koomoa DL, Yco LP, Borsics T, Wallick CJ, Bachmann AS.

Cancer Res. 2008 Dec 1;68(23):9825-31.PMID: 19047162 [PubMed - indexed for MEDLINE]Related articlesFree article

Polyamine synthesis inhibition induces S phase cell cycle arrest in vascular smooth muscle cells.

Odenlund M, Holmqvist B, Baldetorp B, Hellstrand P, Nilsson BO.

Amino Acids. 2009 Feb;36(2):273-82. Epub 2008 Mar 27.PMID: 18368465 [PubMed - indexed for MEDLINE]Related articles

TGFbeta-mediated formation of pRb-E2F complexes in human myeloid leukemia cells.

Hu XT.

Biochem Biophys Res Commun. 2008 May 2;369(2):277-80. Epub 2008 Feb 21. Review.PMID: 18294958 [PubMed - indexed for MEDLINE]Related articles

Effects of antisense RNA targeting of ODC and AdoMetDC on the synthesis of polyamine synthesis and cell growth in prostate cancer cells using a prostatic androgen-dependent promoter in adenovirus.

Li W, Liu X, Wang W, Sun H, Hu Y, Lei H, Liu G, Gao Y.

Prostate. 2008 Sep 1;68(12):1354-61.PMID: 18548481 [PubMed - indexed for MEDLINE]Related articles

Effects of alpha-difluoromethylornithine on the cyclin A expression in Hep-2 cells.

Marty C, Mori G, Sabini L, Rivarola V.

Biocell. 2000 Apr;24(1):49-52.PMID: 10893799 [PubMed - indexed for MEDLINE]Related articles

The retinoblastoma protein and its homolog p130 regulate the G1/S transition in pancreatic beta-cells.

Harb G, Vasavada RC, Cobrinik D, Stewart AF.

Diabetes. 2009 Aug;58(8):1852-62. Epub 2009 Jun 9. Erratum in: Diabetes. 2009 Oct;58(10):2425. PMID: 19509021 [PubMed - indexed for MEDLINE]Related articlesFree article

Normal G1/S transition and prolonged S phase within one cell cycle after seeding cells in the presence of an ornithine decarboxylase inhibitor.

Fredlund JO, Oredsson SM.

Cell Prolif. 1996 Aug;29(8):457-66.PMID: 8918559 [PubMed - indexed for MEDLINE]Related articles

Effects of polyamine depletion by alpha-difluoromethylornithine on in vitro and in vivo biological properties of 4T1 murine mammary cancer cells.

Jun JY, Griffith JW, Bruggeman R, Washington S, Demers LM, Verderame MF, Manni A.

Breast Cancer Res Treat. 2007 Sep;105(1):29-36. Epub 2006 Dec 2.PMID: 17143592 [PubMed - indexed for MEDLINE]Related articles

Inhibition of human ornithine decarboxylase activity by enantiomers of difluoromethylornithine.

Qu N, Ignatenko NA, Yamauchi P, Stringer DE, Levenson C, Shannon P, Perrin S, Gerner EW.

Biochem J. 2003 Oct 15;375(Pt 2):465-70.PMID: 12859253 [PubMed - indexed for MEDLINE]Related articlesFree article

Polyamine depletion partially reduces the radiation-induced cell death via cell cycle delay mediated by thioredoxin.

Moon MS, Kim JS, Kim TL, Yum JJ, Cho EW, Kim IG.

Cell Biol Toxicol. 2006 Mar;22(2):137-47. Epub 2006 Mar 10.PMID: 16532286 [PubMed - indexed for MEDLINE]Related articles

Induction of apoptotic cell death by putrescine.

Takao K, Rickhag M, Hegardt C, Oredsson S, Persson L.

Int J Biochem Cell Biol. 2006;38(4):621-8. Epub 2005 Dec 1.PMID: 16406751 [PubMed - indexed for MEDLINE]Related articles

[Effect of inhibition of polyamine biosynthesis on the growth and telomerase activity of human laryngeal carcinoma cells Hep-2]

Li Y, Fan M, Cao S, Zhang X.

Zhonghua Er Bi Yan Hou Ke Za Zhi. 2001 Aug;36(4):261-3. Chinese. PMID: 12761991 [PubMed - indexed for MEDLINE]Related articles

Modulation of cell proliferation and polyamine metabolism in rat liver cell cultures by the iron chelator O-trensox.

Gaboriau F, Laupen-Chassay C, Pasdeloup N, Pierre JL, Brissot P, Lescoat G.

Biometals. 2006 Dec;19(6):623-32. Epub 2006 Aug 31.PMID: 16944279 [PubMed - indexed for MEDLINE]Related articles

Abnormal DNA synthesis in polyamine deficient cells revealed by bromodeoxyuridine-flow cytometry technique.

Fredlund JO, Johansson M, Baldetorp B, Oredsson SM.

Cell Prolif. 1994 May;27(5):243-56.PMID: 10465009 [PubMed - indexed for MEDLINE]Related articles

Astroglia growth retardation and increased microglia proliferation by lithium and ornithine decarboxylase inhibitor in rat cerebellar cultures: Cytotoxicity by combined lithium and polyamine inhibition.

Gilad GM, Gilad VH.

J Neurosci Res. 2007 Feb 15;85(3):594-601.PMID: 17171700 [PubMed - indexed for MEDLINE]Related articles

Revival of 2-(difluoromethyl)ornithine (DFMO), an inhibitor of polyamine biosynthesis, as a cancer chemopreventive agent.

Raul F.

Biochem Soc Trans. 2007 Apr;35(Pt 2):353-5.PMID: 17371277 [PubMed - indexed for MEDLINE]Related articles

Single chain fragment anti-heparan sulfate antibody targets the polyamine transport system and attenuates polyamine-dependent cell proliferation.

Welch JE, Bengtson P, Svensson K, Wittrup A, Jenniskens GJ, Ten Dam GB, Van Kuppevelt TH, Belting M.

Int J Oncol. 2008 Apr;32(4):749-56.PMID: 18360702 [PubMed - indexed for MEDLINE]Related articles