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    Results: 1 to 20 of 402

    1.

    COOH-terminal clustering of autoantibody and T-cell determinants on the structure of GAD65 provide insights into the molecular basis of autoreactivity.

    Fenalti G, Hampe CS, Arafat Y, Law RH, Banga JP, Mackay IR, Whisstock JC, Buckle AM, Rowley MJ.

    Diabetes. 2008 May;57(5):1293-301. Epub 2008 Jan 9.PMID: 18184926 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    The PEVKEK region of the pyridoxal phosphate binding domain of GAD65 expresses a dominant B cell epitope for type 1 diabetes sera.

    Tong JC, Myers MA, Mackay IR, Zimmet PZ, Rowley MJ.

    Ann N Y Acad Sci. 2002 Apr;958:182-9.PMID: 12021103 [PubMed - indexed for MEDLINE]Related articles

    3.

    Conformational epitopes on the diabetes autoantigen GAD65 identified by peptide phage display and molecular modeling.

    Myers MA, Davies JM, Tong JC, Whisstock J, Scealy M, Mackay IR, Rowley MJ.

    J Immunol. 2000 Oct 1;165(7):3830-8.PMID: 11034389 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    GAD65 as a prototypic autoantigen.

    Fenalti G, Rowley MJ.

    J Autoimmun. 2008 Nov;31(3):228-32. Epub 2008 Jun 2.PMID: 18514483 [PubMed - indexed for MEDLINE]Related articles

    5.

    Autoreactive epitopes defined by diabetes-associated human monoclonal antibodies are localized in the middle and C-terminal domains of the smaller form of glutamate decarboxylase.

    Richter W, Shi Y, Baekkeskov S.

    Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2832-6.PMID: 7681990 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Molecular characterization of a disease associated conformational epitope on GAD65 recognised by a human monoclonal antibody b96.11.

    Fenalti G, Hampe CS, O'connor K, Banga JP, Mackay IR, Rowley MJ, El-Kabbani O.

    Mol Immunol. 2007 Feb;44(6):1178-89. Epub 2006 Aug 22.PMID: 16930708 [PubMed - indexed for MEDLINE]Related articles

    7.

    High-resolution autoreactive epitope mapping and structural modeling of the 65 kDa form of human glutamic acid decarboxylase.

    Schwartz HL, Chandonia JM, Kash SF, Kanaani J, Tunnell E, Domingo A, Cohen FE, Banga JP, Madec AM, Richter W, Baekkeskov S.

    J Mol Biol. 1999 Apr 16;287(5):983-99.PMID: 10222205 [PubMed - indexed for MEDLINE]Related articles

    8.

    GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65.

    Reijonen H, Daniels TL, Lernmark A, Nepom GT.

    Diabetes. 2000 Oct;49(10):1621-6.PMID: 11016444 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Immune reactivity of diabetes-associated human monoclonal autoantibodies defines multiple epitopes and detects two domain boundaries in glutamate decarboxylase.

    Syren K, Lindsay L, Stoehrer B, Jury K, Lühder F, Baekkeskov S, Richter W.

    J Immunol. 1996 Dec 1;157(11):5208-14.PMID: 8943434 [PubMed - indexed for MEDLINE]Related articles

    10.

    Distinct antigenic features of linear epitopes at the N-terminus and C-terminus of 65 kDa glutamic acid decarboxylase (GAD65): implications for autoantigen modification during pathogenesis.

    Al-Bukhari TA, Radford PM, Bouras G, Davenport C, Trigwell SM, Bottazzo GF, Lai M, Schwartz HL, Tighe PJ, Todd I.

    Clin Exp Immunol. 2002 Oct;130(1):131-9.PMID: 12296864 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Higher autoantibody levels and recognition of a linear NH2-terminal epitope in the autoantigen GAD65, distinguish stiff-man syndrome from insulin-dependent diabetes mellitus.

    Kim J, Namchuk M, Bugawan T, Fu Q, Jaffe M, Shi Y, Aanstoot HJ, Turck CW, Erlich H, Lennon V, Baekkeskov S.

    J Exp Med. 1994 Aug 1;180(2):595-606.PMID: 7519242 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401.

    Wicker LS, Chen SL, Nepom GT, Elliott JF, Freed DC, Bansal A, Zheng S, Herman A, Lernmark A, Zaller DM, Peterson LB, Rothbard JB, Cummings R, Whiteley PJ.

    J Clin Invest. 1996 Dec 1;98(11):2597-603.PMID: 8958223 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients.

    Endl J, Otto H, Jung G, Dreisbusch B, Donie F, Stahl P, Elbracht R, Schmitz G, Meinl E, Hummel M, Ziegler AG, Wank R, Schendel DJ.

    J Clin Invest. 1997 May 15;99(10):2405-15.PMID: 9153283 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Murine monoclonal glutamic acid decarboxylase (GAD)65 antibodies recognize autoimmune-associated GAD epitope regions targeted in patients with type 1 diabetes mellitus and stiff-man syndrome.

    Ziegler B, Schlosser M, Lühder F, Strebelow M, Augstein P, Northemann W, Powers AC, Ziegler M.

    Acta Diabetol. 1996 Sep;33(3):225-31.PMID: 8904930 [PubMed - indexed for MEDLINE]Related articles

    15.

    Dynamic changes of GAD65 autoantibody epitope specificities in individuals at risk of developing type 1 diabetes.

    Schlosser M, Banga JP, Madec AM, Binder KA, Strebelow M, Rjasanowski I, Wassmuth R, Gilliam LK, Luo D, Hampe CS.

    Diabetologia. 2005 May;48(5):922-30. Epub 2005 Apr 16.PMID: 15834701 [PubMed - indexed for MEDLINE]Related articles

    16.

    Identification of glutamic acid decarboxylase autoantibody heterogeneity and epitope regions in type I diabetes.

    Ujihara N, Daw K, Gianani R, Boel E, Yu L, Powers AC.

    Diabetes. 1994 Aug;43(8):968-75.PMID: 8039604 [PubMed - indexed for MEDLINE]Related articles

    17.

    Autoantigenic reactivity of diabetes sera with a hybrid glutamic acid decarboxylase GAD67-65 molecule GAD67(1-101)/GAD65(96-585).

    Teoh KL, Fida S, Rowley MJ, Mackay IR.

    Autoimmunity. 1998;28(4):259-66.PMID: 9892508 [PubMed - indexed for MEDLINE]Related articles

    18.

    HLA-DR binding analysis of peptides from islet antigens in IDDM.

    Geluk A, van Meijgaarden KE, Schloot NC, Drijfhout JW, Ottenhoff TH, Roep BO.

    Diabetes. 1998 Oct;47(10):1594-601.PMID: 9753297 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Fusion proteins for combined analysis of autoantibodies to the 65-kDa isoform of glutamic acid decarboxylase and islet antigen-2 in insulin-dependent diabetes mellitus.

    Rickert M, Seissler J, Dangel W, Lorenz H, Richter W.

    Clin Chem. 2001 May;47(5):926-34.PMID: 11325898 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Association of amino-terminal-specific antiglutamate decarboxylase (GAD65) autoantibodies with beta-cell functional reserve and a milder clinical phenotype in patients with GAD65 antibodies and ketosis-prone diabetes mellitus.

    Hampe CS, Nalini R, Maldonado MR, Hall TR, Garza G, Iyer D, Balasubramanyam A.

    J Clin Endocrinol Metab. 2007 Feb;92(2):462-7. Epub 2006 Nov 7.PMID: 17090641 [PubMed - indexed for MEDLINE]Related articlesFree article

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