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    Results: 1 to 20 of 172

    1.

    HNF4 alpha and the Ca-channel TRPC1 are novel disease candidate genes in diabetic nephropathy.

    Niehof M, Borlak J.

    Diabetes. 2008 Apr;57(4):1069-77. Epub 2008 Jan 9.PMID: 18184923 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Evaluation of genetic association and expression reduction of TRPC1 in the development of diabetic nephropathy.

    Zhang D, Freedman BI, Flekac M, Santos E, Hicks PJ, Bowden DW, Efendic S, Brismar K, Gu HF.

    Am J Nephrol. 2009;29(3):244-51. Epub 2008 Sep 19.PMID: 18802326 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Na(+) -glucose transporter-2 messenger ribonucleic acid expression in kidney of diabetic rats correlates with glycemic levels: involvement of hepatocyte nuclear factor-1alpha expression and activity.

    Freitas HS, Anhê GF, Melo KF, Okamoto MM, Oliveira-Souza M, Bordin S, Machado UF.

    Endocrinology. 2008 Feb;149(2):717-24. Epub 2007 Oct 25.PMID: 17962340 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Clinical spectrum associated with hepatocyte nuclear factor-1beta mutations.

    Bellanné-Chantelot C, Chauveau D, Gautier JF, Dubois-Laforgue D, Clauin S, Beaufils S, Wilhelm JM, Boitard C, Noël LH, Velho G, Timsit J.

    Ann Intern Med. 2004 Apr 6;140(7):510-7.PMID: 15068978 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    RSK4 and PAK5 are novel candidate genes in diabetic rat kidney and brain.

    Niehof M, Borlak J.

    Mol Pharmacol. 2005 Mar;67(3):604-11. Epub 2004 Dec 22.PMID: 15615695 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Liver-specific reactivation of the inactivated Hnf-1alpha gene: elimination of liver dysfunction to establish a mouse MODY3 model.

    Lee YH, Magnuson MA, Muppala V, Chen SS.

    Mol Cell Biol. 2003 Feb;23(3):923-32.PMID: 12529398 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Evidence that TRPC1 (transient receptor potential canonical 1) forms a Ca(2+)-permeable channel linked to the regulation of cell volume in liver cells obtained using small interfering RNA targeted against TRPC1.

    Chen J, Barritt GJ.

    Biochem J. 2003 Jul 15;373(Pt 2):327-36.PMID: 12720547 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Expression of the hepatic specific V1 messenger ribonucleic acid of the human growth hormone receptor gene is regulated by hepatic nuclear factor (HNF)-4alpha2 and HNF-4alpha8.

    Goodyer CG, Rhani Z, Zheng H.

    Mol Endocrinol. 2008 Feb;22(2):485-500. Epub 2007 Nov 8.PMID: 17991764 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Increased renal collagen cross-linking and lipid accumulation in nephropathy of Zucker diabetic fatty rats.

    Li Y, Qi Y, Kim MS, Xu KZ, Huang TH, Rong X, Murray M, Yamahara J.

    Diabetes Metab Res Rev. 2008 Sep;24(6):498-506.PMID: 18613221 [PubMed - indexed for MEDLINE]Related articles

    10.

    Analysis of gene expression profiles in insulin-sensitive tissues from pre-diabetic and diabetic Zucker diabetic fatty rats.

    Suh YH, Kim Y, Bang JH, Choi KS, Lee JW, Kim WH, Oh TJ, An S, Jung MH.

    J Mol Endocrinol. 2005 Apr;34(2):299-315.PMID: 15821098 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Molecular genetic analysis of MODY candidate genes in Japanese patients with non-obese juvenile onset diabetes mellitus.

    Kagami-Takasugi M, Katsumata N, Tanaka T, Tajima T, Fujieda K.

    J Pediatr Endocrinol Metab. 2006 Feb;19(2):143-8.PMID: 16562587 [PubMed - indexed for MEDLINE]Related articles

    12.

    Induced TRPC1 expression increases protein phosphatase 2A sensitizing intestinal epithelial cells to apoptosis through inhibition of NF-kappaB activation.

    Marasa BS, Xiao L, Rao JN, Zou T, Liu L, Wang J, Bellavance E, Turner DJ, Wang JY.

    Am J Physiol Cell Physiol. 2008 May;294(5):C1277-87. Epub 2008 Mar 5.PMID: 18322138 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    HNF4alpha and HNF1alpha dysfunction as a molecular rational for cyclosporine induced posttransplantation diabetes mellitus.

    Borlak J, Niehof M.

    PLoS One. 2009;4(3):e4662. Epub 2009 Mar 2.PMID: 19252740 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Preservation of hepatocyte nuclear factor-4alpha is associated with zinc protection against TNF-alpha hepatotoxicity in mice.

    Zhou Z, Kang X, Jiang Y, Song Z, Feng W, McClain CJ, Kang YJ.

    Exp Biol Med (Maywood). 2007 May;232(5):622-8.PMID: 17463158 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Upregulation of TRPC1 in the development of cardiac hypertrophy.

    Ohba T, Watanabe H, Murakami M, Takahashi Y, Iino K, Kuromitsu S, Mori Y, Ono K, Iijima T, Ito H.

    J Mol Cell Cardiol. 2007 Mar;42(3):498-507. Epub 2006 Dec 15.PMID: 17174323 [PubMed - indexed for MEDLINE]Related articles

    16.

    Mechanisms of mutual functional interactions between HNF-4alpha and HNF-1alpha revealed by mutations that cause maturity onset diabetes of the young.

    Rowley CW, Staloch LJ, Divine JK, McCaul SP, Simon TC.

    Am J Physiol Gastrointest Liver Physiol. 2006 Mar;290(3):G466-75. Epub 2005 Oct 13.PMID: 16223942 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Regulatory role of neuron-restrictive silencing factor in expression of TRPC1.

    Ohba T, Watanabe H, Takahashi Y, Suzuki T, Miyoshi I, Nakayama S, Satoh E, Iino K, Sasano H, Mori Y, Kuromitsu S, Imagawa K, Saito Y, Iijima T, Ito H, Murakami M.

    Biochem Biophys Res Commun. 2006 Dec 22;351(3):764-70. Epub 2006 Nov 3.PMID: 17084381 [PubMed - indexed for MEDLINE]Related articles

    18.

    Hepatocyte nuclear factor-1beta gene deletions--a common cause of renal disease.

    Edghill EL, Oram RA, Owens M, Stals KL, Harries LW, Hattersley AT, Ellard S, Bingham C.

    Nephrol Dial Transplant. 2008 Feb;23(2):627-35. Epub 2007 Oct 30.PMID: 17971380 [PubMed - indexed for MEDLINE]Related articles

    19.

    Functional activity of human hepatoma cells transfected with adenovirus-mediated hepatocyte nuclear factor (HNF)-4 gene.

    Naiki T, Nagaki M, Shidoji Y, Kojima H, Moriwaki H.

    Cell Transplant. 2004;13(4):393-403.PMID: 15468681 [PubMed - indexed for MEDLINE]Related articles

    20.

    LR-90 prevents dyslipidaemia and diabetic nephropathy in the Zucker diabetic fatty rat.

    Figarola JL, Loera S, Weng Y, Shanmugam N, Natarajan R, Rahbar S.

    Diabetologia. 2008 May;51(5):882-91. Epub 2008 Mar 4.PMID: 18317729 [PubMed - indexed for MEDLINE]Related articles

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