PubMed

Regulation of Sox9 activity by crosstalk with nuclear factor-kappaB and retinoic acid receptors.

Rockel JS, Kudirka JC, Guzi AJ, Bernier SM.

Arthritis Res Ther. 2008;10(1):R3. Epub 2008 Jan 9.PMID: 18182117 [PubMed - indexed for MEDLINE]Related articlesFree article

Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte.

Klooster AR, Bernier SM.

Arthritis Res Ther. 2005;7(1):R127-38. Epub 2004 Nov 29.PMID: 15642133 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of TGF-beta signaling by proinflammatory cytokines in articular chondrocytes.

Roman-Blas JA, Stokes DG, Jimenez SA.

Osteoarthritis Cartilage. 2007 Dec;15(12):1367-77. Epub 2007 Jun 29.PMID: 17604656 [PubMed - indexed for MEDLINE]Related articlesFree article

JAK/STAT but not ERK1/ERK2 pathway mediates interleukin (IL)-6/soluble IL-6R down-regulation of Type II collagen, aggrecan core, and link protein transcription in articular chondrocytes. Association with a down-regulation of SOX9 expression.

Legendre F, Dudhia J, Pujol JP, Bogdanowicz P.

J Biol Chem. 2003 Jan 31;278(5):2903-12. Epub 2002 Nov 4.PMID: 12419823 [PubMed - indexed for MEDLINE]Related articlesFree article

Transforming growth factor (TGF)-beta-activated kinase 1 mimics and mediates TGF-beta-induced stimulation of type II collagen synthesis in chondrocytes independent of Col2a1 transcription and Smad3 signaling.

Qiao B, Padilla SR, Benya PD.

J Biol Chem. 2005 Apr 29;280(17):17562-71. Epub 2005 Mar 1.PMID: 15743758 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibitory effect of NF-kappaB on 1,25-dihydroxyvitamin D(3) and retinoid X receptor function.

Farmer PK, He X, Schmitz ML, Rubin J, Nanes MS.

Am J Physiol Endocrinol Metab. 2000 Jul;279(1):E213-20.PMID: 10893342 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcriptional Co-activators CREB-binding protein/p300 increase chondrocyte Cd-rap gene expression by multiple mechanisms including sequestration of the repressor CCAAT/enhancer-binding protein.

Imamura T, Imamura C, Iwamoto Y, Sandell LJ.

J Biol Chem. 2005 Apr 29;280(17):16625-34. Epub 2005 Feb 18.PMID: 15722556 [PubMed - indexed for MEDLINE]Related articlesFree article

Potent inhibition of the master chondrogenic factor Sox9 gene by interleukin-1 and tumor necrosis factor-alpha.

Murakami S, Lefebvre V, de Crombrugghe B.

J Biol Chem. 2000 Feb 4;275(5):3687-92.PMID: 10652367 [PubMed - indexed for MEDLINE]Related articlesFree article

All-trans retinoic acid suppresses interleukin-6 expression in interleukin-1-stimulated synovial fibroblasts by inhibition of ERK1/2 pathway independently of RAR activation.

Kirchmeyer M, Koufany M, Sebillaud S, Netter P, Jouzeau JY, Bianchi A.

Arthritis Res Ther. 2008;10(6):R141. Epub 2008 Dec 10.PMID: 19068145 [PubMed - indexed for MEDLINE]Related articlesFree article

Synergistic activation of interleukin-8 gene transcription by all-trans-retinoic acid and tumor necrosis factor-alpha involves the transcription factor NF-kappaB.

Harant H, de Martin R, Andrew PJ, Foglar E, Dittrich C, Lindley IJ.

J Biol Chem. 1996 Oct 25;271(43):26954-61.PMID: 8900181 [PubMed - indexed for MEDLINE]Related articlesFree article

TNF-alpha induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-kappaB/p300 binding in human tracheal smooth muscle cells.

Lee CW, Lin CC, Lin WN, Liang KC, Luo SF, Wu CB, Wang SW, Yang CM.

Am J Physiol Lung Cell Mol Physiol. 2007 Mar;292(3):L799-812. Epub 2006 Dec 8.PMID: 17158602 [PubMed - indexed for MEDLINE]Related articlesFree article

Trans-activation of the mouse cartilage-derived retinoic acid-sensitive protein gene by Sox9.

Xie WF, Zhang X, Sakano S, Lefebvre V, Sandell LJ.

J Bone Miner Res. 1999 May;14(5):757-63.PMID: 10320524 [PubMed - indexed for MEDLINE]Related articles

Tumor necrosis factor alpha induces expression of genes for matrix degradation in human chondrocyte-like HCS-2/8 cells through activation of NF-kappaB: abrogation of the tumor necrosis factor alpha effect by proteasome inhibitors.

Sakai T, Kambe F, Mitsuyama H, Ishiguro N, Kurokouchi K, Takigawa M, Iwata H, Seo H.

J Bone Miner Res. 2001 Jul;16(7):1272-80.PMID: 11450703 [PubMed - indexed for MEDLINE]Related articles

Regulation of vascular smooth muscle cell proliferation by nuclear factor-kappaB and its inhibitor, I-kappaB.

Hoshi S, Goto M, Koyama N, Nomoto K, Tanaka H.

J Biol Chem. 2000 Jan 14;275(2):883-9.PMID: 10625622 [PubMed - indexed for MEDLINE]Related articlesFree article

SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6.

Sekiya I, Tsuji K, Koopman P, Watanabe H, Yamada Y, Shinomiya K, Nifuji A, Noda M.

J Biol Chem. 2000 Apr 14;275(15):10738-44.PMID: 10753864 [PubMed - indexed for MEDLINE]Related articlesFree article

Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNFalpha-induced MEK/ERK signalling.

Rockel JS, Bernier SM, Leask A.

Arthritis Res Ther. 2009;11(1):R8. Epub 2009 Jan 14.PMID: 19144181 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes.

Martin G, Andriamanalijaona R, Grässel S, Dreier R, Mathy-Hartert M, Bogdanowicz P, Boumédiene K, Henrotin Y, Bruckner P, Pujol JP.

Arthritis Rheum. 2004 Nov;50(11):3549-60.PMID: 15529381 [PubMed - indexed for MEDLINE]Related articlesFree article

Coordinate down-regulation of cartilage matrix gene expression in Bcl-2 deficient chondrocytes is associated with decreased SOX9 expression and decreased mRNA stability.

Kinkel MD, Horton WE Jr.

J Cell Biochem. 2003 Apr 1;88(5):941-53.PMID: 12616533 [PubMed - indexed for MEDLINE]Related articles

Comparative effects of IL-1beta and hydrogen peroxide (H2O2) on catabolic and anabolic gene expression in juvenile bovine chondrocytes.

Martin G, Andriamanalijaona R, Mathy-Hartert M, Henrotin Y, Pujol JP.

Osteoarthritis Cartilage. 2005 Oct;13(10):915-24. Epub 2005 Jun 9.PMID: 15950497 [PubMed - indexed for MEDLINE]Related articles

TNFalpha suppresses link protein and type II collagen expression in chondrocytes: Role of MEK1/2 and NF-kappaB signaling pathways.

Séguin CA, Bernier SM.

J Cell Physiol. 2003 Dec;197(3):356-69.PMID: 14566965 [PubMed - indexed for MEDLINE]Related articles