PubMed

DeltaRR vaccination protects from KA-induced seizures and neuronal loss through ICP10PK-mediated modulation of the neuronal-microglial axis.

Laing JM, Aurelian L.

Genet Vaccines Ther. 2008 Jan 7;6:1.PMID: 18179717 [PubMed - in process]Related articlesFree article

The growth compromised HSV-2 mutant DeltaRR prevents kainic acid-induced apoptosis and loss of function in organotypic hippocampal cultures.

Gober MD, Laing JM, Thompson SM, Aurelian L.

Brain Res. 2006 Nov 13;1119(1):26-39. Epub 2006 Oct 3.PMID: 17020750 [PubMed - indexed for MEDLINE]Related articlesFree article

Multi-targeted neuroprotection by the HSV-2 gene ICP10PK includes robust bystander activity through PI3-K/Akt and/or MEK/ERK-dependent neuronal release of vascular endothelial growth factor and fractalkine.

Laing JM, Smith CC, Aurelian L.

J Neurochem. 2010 Feb;112(3):662-76. Epub 2009 Nov 5.PMID: 19891735 [PubMed - indexed for MEDLINE]Related articles

The HSV-2 protein ICP10PK prevents neuronal apoptosis and loss of function in an in vivo model of neurodegeneration associated with glutamate excitotoxicity.

Golembewski EK, Wales SQ, Aurelian L, Yarowsky PJ.

Exp Neurol. 2007 Feb;203(2):381-93. Epub 2006 Oct 16.PMID: 17046754 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth-compromised HSV-2 vector Delta RR protects from N-methyl-D-aspartate-induced neuronal degeneration through redundant activation of the MEK/ERK and PI3-K/Akt survival pathways, either one of which overrides apoptotic cascades.

Laing JM, Golembewski EK, Wales SQ, Liu J, Jafri MS, Yarowsky PJ, Aurelian L.

J Neurosci Res. 2008 Feb 1;86(2):378-91.PMID: 17893911 [PubMed - indexed for MEDLINE]Related articles

Intranasal administration of the growth-compromised HSV-2 vector DeltaRR prevents kainate-induced seizures and neuronal loss in rats and mice.

Laing JM, Gober MD, Golembewski EK, Thompson SM, Gyure KA, Yarowsky PJ, Aurelian L.

Mol Ther. 2006 May;13(5):870-81. Epub 2006 Feb 24. Erratum in: Mol Ther. 2007 Sep;15(9):1734. PMID: 16500153 [PubMed - indexed for MEDLINE]Related articlesFree article

The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection.

Tran TA, McCoy MK, Sporn MB, Tansey MG.

J Neuroinflammation. 2008 May 12;5:14.PMID: 18474101 [PubMed - indexed for MEDLINE]Related articlesFree article

The herpes simplex virus type 2 gene ICP10PK protects from apoptosis caused by nerve growth factor deprivation through inhibition of caspase-3 activation and XIAP up-regulation.

Wales SQ, Li B, Laing JM, Aurelian L.

J Neurochem. 2007 Oct;103(1):365-79.PMID: 17877640 [PubMed - indexed for MEDLINE]Related articlesFree article

Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway.

Pais TF, Figueiredo C, Peixoto R, Braz MH, Chatterjee S.

J Neuroinflammation. 2008 Oct 9;5:43.PMID: 18844999 [PubMed - indexed for MEDLINE]Related articlesFree article

Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity.

Zhang D, Hu X, Wei SJ, Liu J, Gao H, Qian L, Wilson B, Liu G, Hong JS.

J Neuroinflammation. 2008 May 28;5:21.PMID: 18507839 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of microglial IKKbeta in kainic acid-induced hippocampal neuronal cell death.

Cho IH, Hong J, Suh EC, Kim JH, Lee H, Lee JE, Lee S, Kim CH, Kim DW, Jo EK, Lee KE, Karin M, Lee SJ.

Brain. 2008 Nov;131(Pt 11):3019-33. Epub 2008 Sep 26.PMID: 18819987 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced microglial activation and proinflammatory cytokine upregulation are linked to increased susceptibility to seizures and neurologic injury in a 'two-hit' seizure model.

Somera-Molina KC, Nair S, Van Eldik LJ, Watterson DM, Wainwright MS.

Brain Res. 2009 Jul 28;1282:162-72. Epub 2009 Jun 6.PMID: 19501063 [PubMed - indexed for MEDLINE]Related articles

Shikonins attenuate microglial inflammatory responses by inhibition of ERK, Akt, and NF-kappaB: neuroprotective implications.

Nam KN, Son MS, Park JH, Lee EH.

Neuropharmacology. 2008 Oct;55(5):819-25. Epub 2008 Jul 6.PMID: 18657551 [PubMed - indexed for MEDLINE]Related articles

Successful inhibition of excitotoxic neuronal damage and microglial activation after delayed application of interleukin-1 receptor antagonist.

Vogt C, Hailer NP, Ghadban C, Korf HW, Dehghani F.

J Neurosci Res. 2008 Nov 15;86(15):3314-21.PMID: 18646209 [PubMed - indexed for MEDLINE]Related articles

Microglial inhibition of neuroprotection by antagonists of the EP1 prostaglandin E2 receptor.

Carlson NG, Rojas MA, Black JD, Redd JW, Hille J, Hill KE, Rose JW.

J Neuroinflammation. 2009 Feb 17;6:5.PMID: 19222857 [PubMed - indexed for MEDLINE]Related articlesFree article

Monomeric IgG is neuroprotective via enhancing microglial recycling endocytosis and TNF-alpha.

Hulse RE, Swenson WG, Kunkler PE, White DM, Kraig RP.

J Neurosci. 2008 Nov 19;28(47):12199-211.PMID: 19020014 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuronal injury induces the release of pro-interleukin-1beta from activated microglia in vitro.

Wang P, Rothwell NJ, Pinteaux E, Brough D.

Brain Res. 2008 Oct 21;1236:1-7. Epub 2008 Aug 8.PMID: 18722361 [PubMed - indexed for MEDLINE]Related articles

Neuroprotective effects of the anti-inflammatory compound triflusal on ischemia-like neurodegeneration in mouse hippocampal slice cultures occur independent of microglia.

Montero Domínguez M, González B, Zimmer J.

Exp Neurol. 2009 Jul;218(1):11-23. Epub 2009 Mar 31.PMID: 19341733 [PubMed - indexed for MEDLINE]Related articles

2-Arachidonoylglycerol elicits neuroprotective effects on excitotoxically lesioned dentate gyrus granule cells via abnormal-cannabidiol-sensitive receptors on microglial cells.

Kreutz S, Koch M, Böttger C, Ghadban C, Korf HW, Dehghani F.

Glia. 2009 Feb;57(3):286-94.PMID: 18837048 [PubMed - indexed for MEDLINE]Related articles

Glial activation involvement in neuronal death by Japanese Encephalitis Virus infection.

Chen CJ, Ou YC, Lin SY, Raung SL, Liao SL, Lai CY, Chen SY, Chen JH.

J Gen Virol. . [Epub ahead of print]PMID: 20007359 [PubMed - as supplied by publisher]Related articles