PubMed

Quantitative linkage analysis for pancreatic B-cell function and insulin resistance in a large twin cohort.

Falchi M, Wilson SG, Paximadas D, Swaminathan R, Spector TD.

Diabetes. 2008 Apr;57(4):1120-4. Epub 2008 Jan 3.PMID: 18174525 [PubMed - indexed for MEDLINE]Related articlesFree article

Bivariate genome-wide scan for metabolic phenotypes in non-diabetic Chinese individuals from the Stanford, Asia and Pacific Program of Hypertension and Insulin Resistance Family Study.

Chiu YF, Chuang LM, Kao HY, Ho LT, Ting CT, Hung YJ, Chen YD, Donlon T, Curb JD, Quertermous T, Hsiung CA.

Diabetologia. 2007 Aug;50(8):1631-40. Epub 2007 Jun 20.PMID: 17579830 [PubMed - indexed for MEDLINE]Related articles

Quantitative trait loci on chromosome 8q24 for pancreatic beta-cell function and 7q11 for insulin sensitivity in obese nondiabetic white and black families: evidence from genome-wide linkage scans in the NHLBI Hypertension Genetic Epidemiology Network (HyperGEN) study.

An P, Freedman BI, Rich SS, Mandel SA, Arnett DK, Myers RH, Chen YD, Hunt SC, Rao DC.

Diabetes. 2006 Feb;55(2):551-8.PMID: 16443794 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis.

An P, Freedman BI, Hanis CL, Chen YD, Weder AB, Schork NJ, Boerwinkle E, Province MA, Hsiung CA, Wu X, Quertermous T, Rao DC.

Diabetes. 2005 Mar;54(3):909-14.PMID: 15734873 [PubMed - indexed for MEDLINE]Related articlesFree article

A major locus for fasting insulin concentrations and insulin resistance on chromosome 6q with strong pleiotropic effects on obesity-related phenotypes in nondiabetic Mexican Americans.

Duggirala R, Blangero J, Almasy L, Arya R, Dyer TD, Williams KL, Leach RJ, O'Connell P, Stern MP.

Am J Hum Genet. 2001 May;68(5):1149-64. Epub 2001 Mar 29.PMID: 11283790 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome-wide linkage scan of insulin level derived traits: the Amish Family Diabetes Study.

Hsueh WC, Silver KD, Pollin TI, Bell CJ, O'Connell JR, Mitchell BD, Shuldiner AR.

Diabetes. 2007 Oct;56(10):2643-8. Epub 2007 Jul 23.PMID: 17646211 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin sensitivity and insulin secretion determined by homeostasis model assessment and risk of diabetes in a multiethnic cohort of women: the Women's Health Initiative Observational Study.

Song Y, Manson JE, Tinker L, Howard BV, Kuller LH, Nathan L, Rifai N, Liu S.

Diabetes Care. 2007 Jul;30(7):1747-52. Epub 2007 Apr 27.PMID: 17468352 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide scan for metabolic syndrome and related quantitative traits in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25.

Ng MC, So WY, Lam VK, Cockram CS, Bell GI, Cox NJ, Chan JC.

Diabetes. 2004 Oct;53(10):2676-83.PMID: 15448100 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic mapping of disposition index and acute insulin response loci on chromosome 11q. The Insulin Resistance Atherosclerosis Study (IRAS) Family Study.

Palmer ND, Langefeld CD, Campbell JK, Williams AH, Saad M, Norris JM, Haffner SM, Rotter JI, Wagenknecht LE, Bergman RN, Rich SS, Bowden DW.

Diabetes. 2006 Apr;55(4):911-8.PMID: 16567510 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome-screen of a large twin cohort reveals linkage for quantitative ultrasound of the calcaneus to 2q33-37 and 4q12-21.

Wilson SG, Reed PW, Andrew T, Barber MJ, Lindersson M, Langdown M, Thompson D, Thompson E, Bailey M, Chiano M, Kleyn PW, Spector TD.

J Bone Miner Res. 2004 Feb;19(2):270-7. Epub 2003 Dec 16.PMID: 14969397 [PubMed - indexed for MEDLINE]Related articles

No evidence of linkage between the very-low-density lipoprotein receptor gene and fasting serum insulin or homeostasis model assessment insulin resistance index: the National Heart, Lung, and Blood Institute Family Heart Study.

Hong Y, Leppert MF, Lin J, Hunt SC, Rich SS, Arnett DK, Myers RH, Eckfeldt J, Williams RR, Province MA.

Metabolism. 2000 Mar;49(3):293-7.PMID: 10726903 [PubMed - indexed for MEDLINE]Related articles

Identification of quantitative trait loci for glucose homeostasis: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study.

Rich SS, Bowden DW, Haffner SM, Norris JM, Saad MF, Mitchell BD, Rotter JI, Langefeld CD, Wagenknecht LE, Bergman RN; Insulin Resistance Atherosclerosis Study Family Study.

Diabetes. 2004 Jul;53(7):1866-75.PMID: 15220212 [PubMed - indexed for MEDLINE]Related articlesFree article

Coincident linkage of fasting plasma insulin and blood pressure to chromosome 7q in hypertensive hispanic families.

Cheng LS, Davis RC, Raffel LJ, Xiang AH, Wang N, Quiñones M, Wen PZ, Toscano E, Diaz J, Pressman S, Henderson PC, Azen SP, Hsueh WA, Buchanan TA, Rotter JI.

Circulation. 2001 Sep 11;104(11):1255-60.PMID: 11551876 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis indicates that a variant GATA-binding site in the PIK3CB promoter is a Cis-acting expression quantitative trait locus for this gene and attenuates insulin resistance in obese children.

Le Stunff C, Dechartres A, Mariot V, Lotton C, Trainor C, Miraglia Del Giudice E, Meyre D, Bieche I, Laurendeau I, Froguel P, Zelenika D, Fallin D, Lathrop M, Roméo PH, Bougnères P.

Diabetes. 2008 Feb;57(2):494-502. Epub 2007 Oct 31.PMID: 17977952 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term effect of bezafibrate on pancreatic beta-cell function and insulin resistance in patients with diabetes.

Tenenbaum H, Behar S, Boyko V, Adler Y, Fisman EZ, Tanne D, Lapidot M, Schwammenthal E, Feinberg M, Matas Z, Motro M, Tenenbaum A.

Atherosclerosis. 2007 Sep;194(1):265-71. Epub 2006 Sep 12.PMID: 16970952 [PubMed - indexed for MEDLINE]Related articles

Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation.

Sparsø T, Andersen G, Albrechtsen A, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Wasson J, Permutt MA, Glaser B, Madsbad S, Pedersen O, Hansen T.

Diabetologia. 2008 Sep;51(9):1646-52. Epub 2008 Jun 21.PMID: 18568334 [PubMed - indexed for MEDLINE]Related articles

Genome-wide scans reveal quantitative trait Loci on 8p and 13q related to insulin action and glucose metabolism: the San Antonio Family Heart Study.

Cai G, Cole SA, Freeland-Graves JH, MacCluer JW, Blangero J, Comuzzie AG.

Diabetes. 2004 May;53(5):1369-74.PMID: 15111508 [PubMed - indexed for MEDLINE]Related articlesFree article

Linkage analysis of factors underlying insulin resistance: Strong Heart Family Study.

North KE, Almasy L, Göring HH, Cole SA, Diego VP, Laston S, Cantu T, Williams JT, Howard BV, Lee ET, Best LG, Fabsitz RR, MacCluer JW.

Obes Res. 2005 Nov;13(11):1877-84.PMID: 16339117 [PubMed - indexed for MEDLINE]Related articles

Linkage and potential association of obesity-related phenotypes with two genes on chromosome 12q24 in a female dizygous twin cohort.

Wilson SG, Adam G, Langdown M, Reneland R, Braun A, Andrew T, Surdulescu GL, Norberg M, Dudbridge F, Reed PW, Sambrook PN, Kleyn PW, Spector TD.

Eur J Hum Genet. 2006 Mar;14(3):340-8.PMID: 16391564 [PubMed - indexed for MEDLINE]Related articlesFree article

Heritability estimates for beta cell function and features of the insulin resistance syndrome in UK families with an increased susceptibility to type 2 diabetes.

Mills GW, Avery PJ, McCarthy MI, Hattersley AT, Levy JC, Hitman GA, Sampson M, Walker M.

Diabetologia. 2004 Apr;47(4):732-8.PMID: 15298351 [PubMed - indexed for MEDLINE]Related articles