PubMed

Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.

Omori S, Tanaka Y, Takahashi A, Hirose H, Kashiwagi A, Kaku K, Kawamori R, Nakamura Y, Maeda S.

Diabetes. 2008 Mar;57(3):791-5. Epub 2007 Dec 27.PMID: 18162508 [PubMed - indexed for MEDLINE]Related articlesFree article

Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening.

Tabara Y, Osawa H, Kawamoto R, Onuma H, Shimizu I, Miki T, Kohara K, Makino H.

Diabetes. 2009 Feb;58(2):493-8. Epub 2008 Nov 25.PMID: 19033397 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.

Wu Y, Li H, Loos RJ, Yu Z, Ye X, Chen L, Pan A, Hu FB, Lin X.

Diabetes. 2008 Oct;57(10):2834-42. Epub 2008 Jul 15.PMID: 18633108 [PubMed - indexed for MEDLINE]Related articlesFree article

Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population.

Lee YH, Kang ES, Kim SH, Han SJ, Kim CH, Kim HJ, Ahn CW, Cha BS, Nam M, Nam CM, Lee HC.

J Hum Genet. 2008;53(11-12):991-8. Epub 2008 Nov 11.PMID: 18991055 [PubMed - indexed for MEDLINE]Related articles

Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.

Grarup N, Rose CS, Andersson EA, Andersen G, Nielsen AL, Albrechtsen A, Clausen JO, Rasmussen SS, Jørgensen T, Sandbaek A, Lauritzen T, Schmitz O, Hansen T, Pedersen O.

Diabetes. 2007 Dec;56(12):3105-11. Epub 2007 Sep 7.PMID: 17827400 [PubMed - indexed for MEDLINE]Related articlesFree article

Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.

Horikoshi M, Hara K, Ito C, Shojima N, Nagai R, Ueki K, Froguel P, Kadowaki T.

Diabetologia. 2007 Dec;50(12):2461-6. Epub 2007 Oct 10.PMID: 17928989 [PubMed - indexed for MEDLINE]Related articles

Variants of the PPARG, IGF2BP2, CDKAL1, HHEX, and TCF7L2 genes confer risk of type 2 diabetes independently of BMI in the German KORA studies.

Herder C, Rathmann W, Strassburger K, Finner H, Grallert H, Huth C, Meisinger C, Gieger C, Martin S, Giani G, Scherbaum WA, Wichmann HE, Illig T.

Horm Metab Res. 2008 Oct;40(10):722-6. Epub 2008 Jul 2.PMID: 18597214 [PubMed - indexed for MEDLINE]Related articles

Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians.

Rong R, Hanson RL, Ortiz D, Wiedrich C, Kobes S, Knowler WC, Bogardus C, Baier LJ.

Diabetes. 2009 Feb;58(2):478-88. Epub 2008 Nov 13.PMID: 19008344 [PubMed - indexed for MEDLINE]Related articlesFree article

Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians.

Ng MC, Park KS, Oh B, Tam CH, Cho YM, Shin HD, Lam VK, Ma RC, So WY, Cho YS, Kim HL, Lee HK, Chan JC, Cho NH.

Diabetes. 2008 Aug;57(8):2226-33. Epub 2008 May 9.PMID: 18469204 [PubMed - indexed for MEDLINE]Related articlesFree article

Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan.

Horikawa Y, Miyake K, Yasuda K, Enya M, Hirota Y, Yamagata K, Hinokio Y, Oka Y, Iwasaki N, Iwamoto Y, Yamada Y, Seino Y, Maegawa H, Kashiwagi A, Yamamoto K, Tokunaga K, Takeda J, Kasuga M.

J Clin Endocrinol Metab. 2008 Aug;93(8):3136-41. Epub 2008 May 13.PMID: 18477659 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population.

Cho YM, Kim TH, Lim S, Choi SH, Shin HD, Lee HK, Park KS, Jang HC.

Diabetologia. 2009 Feb;52(2):253-61. Epub 2008 Nov 11.PMID: 19002430 [PubMed - indexed for MEDLINE]Related articles

Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program.

Moore AF, Jablonski KA, McAteer JB, Saxena R, Pollin TI, Franks PW, Hanson RL, Shuldiner AR, Knowler WC, Altshuler D, Florez JC; Diabetes Prevention Program Research Group.

Diabetes. 2008 Sep;57(9):2503-10. Epub 2008 Jun 10.PMID: 18544707 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk.

Sanghera DK, Ortega L, Han S, Singh J, Ralhan SK, Wander GS, Mehra NK, Mulvihill JJ, Ferrell RE, Nath SK, Kamboh MI.

BMC Med Genet. 2008 Jul 3;9:59.PMID: 18598350 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study).

Hertel JK, Johansson S, Raeder H, Midthjell K, Lyssenko V, Groop L, Molven A, Njølstad PR.

Diabetologia. 2008 Jun;51(6):971-7. Epub 2008 Apr 24.PMID: 18437351 [PubMed - indexed for MEDLINE]Related articles

Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.

Takeuchi F, Serizawa M, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Katsuya T, Miyagishi M, Nakashima N, Nawata H, Nakamura J, Kono S, Takayanagi R, Kato N.

Diabetes. 2009 Jul;58(7):1690-9. Epub 2009 Apr 28.PMID: 19401414 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion.

Kirchhoff K, Machicao F, Haupt A, Schäfer SA, Tschritter O, Staiger H, Stefan N, Häring HU, Fritsche A.

Diabetologia. 2008 Apr;51(4):597-601. Epub 2008 Feb 9.PMID: 18264689 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms in the IDE-KIF11-HHEX gene locus are reproducibly associated with type 2 diabetes in a Japanese population.

Furukawa Y, Shimada T, Furuta H, Matsuno S, Kusuyama A, Doi A, Nishi M, Sasaki H, Sanke T, Nanjo K.

J Clin Endocrinol Metab. 2008 Jan;93(1):310-4. Epub 2007 Oct 30.PMID: 17971426 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function.

Pascoe L, Tura A, Patel SK, Ibrahim IM, Ferrannini E, Zeggini E, Weedon MN, Mari A, Hattersley AT, McCarthy MI, Frayling TM, Walker M; RISC Consortium; U.K. Type 2 Diabetes Genetics Consortium.

Diabetes. 2007 Dec;56(12):3101-4. Epub 2007 Sep 5.PMID: 17804762 [PubMed - indexed for MEDLINE]Related articlesFree article

Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies.

Lewis JP, Palmer ND, Hicks PJ, Sale MM, Langefeld CD, Freedman BI, Divers J, Bowden DW.

Diabetes. 2008 Aug;57(8):2220-5. Epub 2008 Apr 28.PMID: 18443202 [PubMed - indexed for MEDLINE]Related articlesFree article

Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value.

Cauchi S, Meyre D, Durand E, Proença C, Marre M, Hadjadj S, Choquet H, De Graeve F, Gaget S, Allegaert F, Delplanque J, Permutt MA, Wasson J, Blech I, Charpentier G, Balkau B, Vergnaud AC, Czernichow S, Patsch W, Chikri M, Glaser B, Sladek R, Froguel P.

PLoS One. 2008 May 7;3(5):e2031.PMID: 18461161 [PubMed - indexed for MEDLINE]Related articlesFree article