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    Results: 1 to 20 of 1593

    1.

    Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.

    Granata R, Settanni F, Gallo D, Trovato L, Biancone L, Cantaluppi V, Nano R, Annunziata M, Campiglia P, Arnoletti E, Ghè C, Volante M, Papotti M, Muccioli G, Ghigo E.

    Diabetes. 2008 Apr;57(4):967-79. Epub 2007 Dec 27.PMID: 18162507 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3',5'-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-Kinase/Akt signaling.

    Granata R, Settanni F, Biancone L, Trovato L, Nano R, Bertuzzi F, Destefanis S, Annunziata M, Martinetti M, Catapano F, Ghè C, Isgaard J, Papotti M, Ghigo E, Muccioli G.

    Endocrinology. 2007 Feb;148(2):512-29. Epub 2006 Oct 26.PMID: 17068144 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Glucagon-like peptide 1 induces pancreatic beta-cell proliferation via transactivation of the epidermal growth factor receptor.

    Buteau J, Foisy S, Joly E, Prentki M.

    Diabetes. 2003 Jan;52(1):124-32.PMID: 12502502 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Glucagon-like peptide-1 protects beta cells from cytokine-induced apoptosis and necrosis: role of protein kinase B.

    Li L, El-Kholy W, Rhodes CJ, Brubaker PL.

    Diabetologia. 2005 Jul;48(7):1339-49. Epub 2005 May 19.PMID: 15902400 [PubMed - indexed for MEDLINE]Related articles

    5.

    Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator-alpha and DUSP14.

    Klinger S, Poussin C, Debril MB, Dolci W, Halban PA, Thorens B.

    Diabetes. 2008 Mar;57(3):584-93. Epub 2007 Nov 19.PMID: 18025410 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function.

    Park S, Dong X, Fisher TL, Dunn S, Omer AK, Weir G, White MF.

    J Biol Chem. 2006 Jan 13;281(2):1159-68. Epub 2005 Nov 4.PMID: 16272563 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic beta-cells.

    D'Alessandris C, Andreozzi F, Federici M, Cardellini M, Brunetti A, Ranalli M, Del Guerra S, Lauro D, Del Prato S, Marchetti P, Lauro R, Sesti G.

    FASEB J. 2004 Jun;18(9):959-61. Epub 2004 Apr 1.PMID: 15059979 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    A specific increased expression of insulin receptor substrate 2 in pancreatic beta-cell lines is involved in mediating serum-stimulated beta-cell growth.

    Schuppin GT, Pons S, Hügl S, Aiello LP, King GL, White M, Rhodes CJ.

    Diabetes. 1998 Jul;47(7):1074-85.PMID: 9648831 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Effects of ghrelin and other neuropeptides (CART, MCH, orexin A and B, and GLP-1) on the release of insulin from isolated rat islets.

    Colombo M, Gregersen S, Xiao J, Hermansen K.

    Pancreas. 2003 Aug;27(2):161-6.PMID: 12883265 [PubMed - indexed for MEDLINE]Related articles

    10.

    Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells.

    Bouzakri K, Ribaux P, Tomas A, Parnaud G, Rickenbach K, Halban PA.

    Diabetes. 2008 May;57(5):1195-204. Epub 2008 Feb 14.PMID: 18276765 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways.

    Wente W, Efanov AM, Brenner M, Kharitonenkov A, Köster A, Sandusky GE, Sewing S, Treinies I, Zitzer H, Gromada J.

    Diabetes. 2006 Sep;55(9):2470-8.PMID: 16936195 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Ghrelin inhibit cell apoptosis in pancreatic beta cell line HIT-T15 via mitogen-activated protein kinase/phosphoinositide 3-kinase pathways.

    Zhang Y, Ying B, Shi L, Fan H, Yang D, Xu D, Wei Y, Hu X, Zhang Y, Zhang X, Wang T, Liu D, Dou L, Chen G, Jiang F, Wen F.

    Toxicology. 2007 Jul 31;237(1-3):194-202. Epub 2007 May 21.PMID: 17602820 [PubMed - indexed for MEDLINE]Related articles

    13.

    Durable islet effects on insulin secretion and protein kinase A expression following exendin-4 treatment of high-fat diet-fed mice.

    Winzell MS, Ahrén B.

    J Mol Endocrinol. 2008 Feb;40(2):93-100.PMID: 18234911 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Exendin-4 and exercise promotes beta-cell function and mass through IRS2 induction in islets of diabetic rats.

    Park S, Hong SM, Sung SR.

    Life Sci. 2008 Feb 27;82(9-10):503-11. Epub 2007 Dec 31.PMID: 18237751 [PubMed - indexed for MEDLINE]Related articles

    15.

    Activation of glucagon-like peptide-1 receptor signaling does not modify the growth or apoptosis of human pancreatic cancer cells.

    Koehler JA, Drucker DJ.

    Diabetes. 2006 May;55(5):1369-79.PMID: 16644694 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    beta-Cell Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1.

    Li Y, Cao X, Li LX, Brubaker PL, Edlund H, Drucker DJ.

    Diabetes. 2005 Feb;54(2):482-91.PMID: 15677506 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    The common Arg972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets.

    Federici M, Hribal ML, Ranalli M, Marselli L, Porzio O, Lauro D, Borboni P, Lauro R, Marchetti P, Melino G, Sesti G.

    FASEB J. 2001 Jan;15(1):22-24. Epub 2000 Nov 14.PMID: 11099486 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Beta-Arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic beta cells.

    Sonoda N, Imamura T, Yoshizaki T, Babendure JL, Lu JC, Olefsky JM.

    Proc Natl Acad Sci U S A. 2008 May 6;105(18):6614-9. Epub 2008 Apr 29.PMID: 18445652 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells.

    Fontés G, Semache M, Hagman DK, Tremblay C, Shah R, Rhodes CJ, Rutter J, Poitout V.

    Diabetes. 2009 Sep;58(9):2048-58. Epub 2009 Jun 5.PMID: 19502418 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic beta-cell mass.

    Buteau J, Spatz ML, Accili D.

    Diabetes. 2006 May;55(5):1190-6.PMID: 16644672 [PubMed - indexed for MEDLINE]Related articlesFree article

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