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    Results: 1 to 20 of 118

    1.

    Simulating non-small cell lung cancer with a multiscale agent-based model.

    Wang Z, Zhang L, Sagotsky J, Deisboeck TS.

    Theor Biol Med Model. 2007 Dec 21;4:50.PMID: 18154660 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Cross-scale, cross-pathway evaluation using an agent-based non-small cell lung cancer model.

    Wang Z, Birch CM, Sagotsky J, Deisboeck TS.

    Bioinformatics. 2009 Sep 15;25(18):2389-96. Epub 2009 Jul 4.PMID: 19578172 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Simulating the impact of a molecular 'decision-process' on cellular phenotype and multicellular patterns in brain tumors.

    Athale C, Mansury Y, Deisboeck TS.

    J Theor Biol. 2005 Apr 21;233(4):469-81. Epub 2004 Nov 30. Erratum in: J Theor Biol. 2006 Apr 21;239(4):516-7. PMID: 15748909 [PubMed - indexed for MEDLINE]Related articles

    4.

    A multiscale computational approach to dissect early events in the Erb family receptor mediated activation, differential signaling, and relevance to oncogenic transformations.

    Liu Y, Purvis J, Shih A, Weinstein J, Agrawal N, Radhakrishnan R.

    Ann Biomed Eng. 2007 Jun;35(6):1012-25. Epub 2007 Feb 2.PMID: 17273938 [PubMed - indexed for MEDLINE]Related articles

    5.

    Development of a three-dimensional multiscale agent-based tumor model: simulating gene-protein interaction profiles, cell phenotypes and multicellular patterns in brain cancer.

    Zhang L, Athale CA, Deisboeck TS.

    J Theor Biol. 2007 Jan 7;244(1):96-107. Epub 2006 Jul 27.PMID: 16949103 [PubMed - indexed for MEDLINE]Related articles

    6.

    Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy.

    Thomson S, Petti F, Sujka-Kwok I, Epstein D, Haley JD.

    Clin Exp Metastasis. 2008;25(8):843-54. Epub 2008 Aug 12.PMID: 18696232 [PubMed - indexed for MEDLINE]Related articles

    7.

    Cooperative interaction between protein inhibitor of activated signal transducer and activator of transcription-3 with epidermal growth factor receptor blockade in lung cancer.

    Kluge A, Dabir S, Kern J, Nethery D, Halmos B, Ma P, Dowlati A.

    Int J Cancer. 2009 Oct 1;125(7):1728-34.PMID: 19569236 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Computational modelling of cancerous mutations in the EGFR/ERK signalling pathway.

    Orton RJ, Adriaens ME, Gormand A, Sturm OE, Kolch W, Gilbert DR.

    BMC Syst Biol. 2009 Oct 5;3:100.PMID: 19804630 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Laser capture microdissection and protein microarray analysis of human non-small cell lung cancer: differential epidermal growth factor receptor (EGPR) phosphorylation events associated with mutated EGFR compared with wild type.

    VanMeter AJ, Rodriguez AS, Bowman ED, Jen J, Harris CC, Deng J, Calvert VS, Silvestri A, Fredolini C, Chandhoke V, Petricoin EF 3rd, Liotta LA, Espina V.

    Mol Cell Proteomics. 2008 Oct;7(10):1902-24. Epub 2008 Aug 6.PMID: 18687633 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    From pathway to population--a multiscale model of juxtacrine EGFR-MAPK signalling.

    Walker DC, Georgopoulos NT, Southgate J.

    BMC Syst Biol. 2008 Nov 26;2:102.PMID: 19036127 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Tumor dependence on the EGFR signaling pathway expressed by the p-EGFR:p-AKT ratio predicts erlotinib sensitivity in human non-small cell lung cancer (NSCLC) cells expressing wild-type EGFR gene.

    Li T, Ling YH, Perez-Soler R.

    J Thorac Oncol. 2008 Jun;3(6):643-7.PMID: 18520805 [PubMed - indexed for MEDLINE]Related articles

    12.

    The effects of EGF-receptor density on multiscale tumor growth patterns.

    Athale CA, Deisboeck TS.

    J Theor Biol. 2006 Feb 21;238(4):771-9. Epub 2005 Aug 26.PMID: 16126230 [PubMed - indexed for MEDLINE]Related articles

    13.

    Role of alpha7-nicotinic acetylcholine receptor in human non-small cell lung cancer proliferation.

    Paleari L, Catassi A, Ciarlo M, Cavalieri Z, Bruzzo C, Servent D, Cesario A, Chessa L, Cilli M, Piccardi F, Granone P, Russo P.

    Cell Prolif. 2008 Dec;41(6):936-59. Erratum in: Cell Prolif. 2009 Aug;42(4):568. Cell Prolif. 2009 Feb;42(1):122. PMID: 19040571 [PubMed - indexed for MEDLINE]Related articles

    14.

    Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells.

    Giovannetti E, Lemos C, Tekle C, Smid K, Nannizzi S, Rodriguez JA, Ricciardi S, Danesi R, Giaccone G, Peters GJ.

    Mol Pharmacol. 2008 Apr;73(4):1290-300. Epub 2008 Jan 10.PMID: 18187583 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Genetic predictors of MEK dependence in non-small cell lung cancer.

    Pratilas CA, Hanrahan AJ, Halilovic E, Persaud Y, Soh J, Chitale D, Shigematsu H, Yamamoto H, Sawai A, Janakiraman M, Taylor BS, Pao W, Toyooka S, Ladanyi M, Gazdar A, Rosen N, Solit DB.

    Cancer Res. 2008 Nov 15;68(22):9375-83.PMID: 19010912 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Simulating Brain Tumor Heterogeneity with a Multiscale Agent-Based Model: Linking Molecular Signatures, Phenotypes and Expansion Rate.

    Zhang L, Strouthos CG, Wang Z, Deisboeck TS.

    Math Comput Model. 2009 Jan 1;49(1-2):307-319.PMID: 20047002 [PubMed]Related articlesFree article

    17.

    Jab1 is a target of EGFR signaling in ERalpha-negative breast cancer.

    Wang J, Barnes RO, West NR, Olson M, Chu JE, Watson PH.

    Breast Cancer Res. 2008;10(3):R51. Epub 2008 Jun 6.PMID: 18534028 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Intratumoral epiregulin is a marker of advanced disease in non-small cell lung cancer patients and confers invasive properties on EGFR-mutant cells.

    Zhang J, Iwanaga K, Choi KC, Wislez M, Raso MG, Wei W, Wistuba II, Kurie JM.

    Cancer Prev Res (Phila Pa). 2008 Aug;1(3):201-7. Epub 2008 Mar 31.PMID: 19138957 [PubMed - indexed for MEDLINE]Related articles

    19.

    Targeted therapy in advanced non-small-cell lung cancer.

    Gettinger S.

    Semin Respir Crit Care Med. 2008 Jun;29(3):291-301. Review.PMID: 18506667 [PubMed - indexed for MEDLINE]Related articles

    20.

    TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation.

    Oberst MD, Beberman SJ, Zhao L, Yin JJ, Ward Y, Kelly K.

    BMC Cancer. 2008 Jul 2;8:189.PMID: 18597688 [PubMed - indexed for MEDLINE]Related articlesFree article

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