PubMed

Synergy between leptin therapy and a seemingly negligible amount of voluntary wheel running prevents progression of dietary obesity in leptin-resistant rats.

Shapiro A, Matheny M, Zhang Y, Tümer N, Cheng KY, Rogrigues E, Zolotukhin S, Scarpace PJ.

Diabetes. 2008 Mar;57(3):614-22. Epub 2007 Dec 17.PMID: 18086903 [PubMed - indexed for MEDLINE]Related articlesFree article

Central leptin gene therapy fails to overcome leptin resistance associated with diet-induced obesity.

Wilsey J, Zolotukhin S, Prima V, Scarpace PJ.

Am J Physiol Regul Integr Comp Physiol. 2003 Nov;285(5):R1011-20.PMID: 14557234 [PubMed - indexed for MEDLINE]Related articles

Voluntary wheel running decreases adipose tissue mass and expression of leptin mRNA in Osborne-Mendel rats.

Zachwieja JJ, Hendry SL, Smith SR, Harris RB.

Diabetes. 1997 Jul;46(7):1159-66.PMID: 9200651 [PubMed - indexed for MEDLINE]Related articles

Modulation of central leptin sensitivity and energy balance in a rat model of diet-induced obesity.

Fam BC, Morris MJ, Hansen MJ, Kebede M, Andrikopoulos S, Proietto J, Thorburn AW.

Diabetes Obes Metab. 2007 Nov;9(6):840-52.PMID: 17924866 [PubMed - indexed for MEDLINE]Related articles

Characterization of the resistance to the anorectic and endocrine effects of leptin in obesity-prone and obesity-resistant rats fed a high-fat diet.

Tulipano G, Vergoni AV, Soldi D, Muller EE, Cocchi D.

J Endocrinol. 2004 Nov;183(2):289-98.PMID: 15531717 [PubMed - indexed for MEDLINE]Related articlesFree article

Prolonged hyperphagia with high-fat feeding contributes to exacerbated weight gain in rats with adult-onset obesity.

Judge MK, Zhang J, Tümer N, Carter C, Daniels MJ, Scarpace PJ.

Am J Physiol Regul Integr Comp Physiol. 2008 Sep;295(3):R773-80. Epub 2008 Jul 2.PMID: 18596107 [PubMed - indexed for MEDLINE]Related articlesFree article

Chronic exercise lowers the defended body weight gain and adiposity in diet-induced obese rats.

Levin BE, Dunn-Meynell AA.

Am J Physiol Regul Integr Comp Physiol. 2004 Apr;286(4):R771-8. Epub 2003 Dec 24.PMID: 14695115 [PubMed - indexed for MEDLINE]Related articles

Leptin resistance exacerbates diet-induced obesity and is associated with diminished maximal leptin signalling capacity in rats.

Scarpace PJ, Matheny M, Tümer N, Cheng KY, Zhang Y.

Diabetologia. 2005 Jun;48(6):1075-83. Epub 2005 Apr 30.PMID: 15864530 [PubMed - indexed for MEDLINE]Related articles

Serum and gene expression levels of leptin and adiponectin in rats susceptible or resistant to diet-induced obesity.

Pérez-Echarri N, Pérez-Matute P, Martínez JA, Marti A, Moreno-Aliaga MJ.

J Physiol Biochem. 2005 Jun;61(2):333-42.PMID: 16180331 [PubMed - indexed for MEDLINE]Related articles

Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding.

Shapiro A, Mu W, Roncal C, Cheng KY, Johnson RJ, Scarpace PJ.

Am J Physiol Regul Integr Comp Physiol. 2008 Nov;295(5):R1370-5. Epub 2008 Aug 13.PMID: 18703413 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin antagonist reverses hypertension caused by leptin overexpression, but fails to normalize obesity-related hypertension.

Tümer N, Erdös B, Matheny M, Cudykier I, Scarpace PJ.

J Hypertens. 2007 Dec;25(12):2471-8.PMID: 17984669 [PubMed - indexed for MEDLINE]Related articles

Novel black soy peptides with antiobesity effects: activation of leptin-like signaling and AMP-activated protein kinase.

Jang EH, Moon JS, Ko JH, Ahn CW, Lee HH, Shin JK, Park CS, Kang JH.

Int J Obes (Lond). 2008 Jul;32(7):1161-70. Epub 2008 Apr 15.PMID: 18414417 [PubMed - indexed for MEDLINE]Related articles

Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity.

El-Haschimi K, Pierroz DD, Hileman SM, Bjørbaek C, Flier JS.

J Clin Invest. 2000 Jun;105(12):1827-32.PMID: 10862798 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of exercise on body weight gain and adiposity in obesity-prone and -resistant rats.

Levin BE, Dunn-Meynell AA.

Int J Obes (Lond). 2006 Apr;30(4):722-7.PMID: 16404411 [PubMed - indexed for MEDLINE]Related articles

Possible role of triacylglycerol-rich lipoproteins in the down-regulation of adipose obese mRNA expression in rats re-fed a high-fat diet.

Chang ML, Chen HL, Lu SC.

J Biomed Sci. 2005;12(4):621-8. Epub 2005 Nov 10.PMID: 16132107 [PubMed - indexed for MEDLINE]Related articles

Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling before obesity onset.

Levin BE, Dunn-Meynell AA, Banks WA.

Am J Physiol Regul Integr Comp Physiol. 2004 Jan;286(1):R143-50. Epub 2003 Sep 4.PMID: 12958061 [PubMed - indexed for MEDLINE]Related articles

Three weeks of early-onset exercise prolongs obesity resistance in DIO rats after exercise cessation.

Patterson CM, Dunn-Meynell AA, Levin BE.

Am J Physiol Regul Integr Comp Physiol. 2008 Feb;294(2):R290-301. Epub 2007 Nov 7.PMID: 17989137 [PubMed - indexed for MEDLINE]Related articles

Central overexpression of leptin antagonist reduces wheel running and underscores importance of endogenous leptin receptor activity in energy homeostasis.

Matheny M, Zhang Y, Shapiro A, Tümer N, Scarpace PJ.

Am J Physiol Regul Integr Comp Physiol. 2009 Nov;297(5):R1254-61. Epub 2009 Sep 2.PMID: 19726711 [PubMed - in process]Related articles

Weight gain induced by high-fat feeding involves increased liver oxidative stress.

Milagro FI, Campión J, Martínez JA.

Obesity (Silver Spring). 2006 Jul;14(7):1118-23.PMID: 16899792 [PubMed - indexed for MEDLINE]Related articles

Modulation of susceptibility to weight gain and insulin resistance in low birthweight rats by treatment of their mothers with leptin during pregnancy and lactation.

Stocker C, O'Dowd J, Morton NM, Wargent E, Sennitt MV, Hislop D, Glund S, Seckl JR, Arch JR, Cawthorne MA.

Int J Obes Relat Metab Disord. 2004 Jan;28(1):129-36.PMID: 14557827 [PubMed - indexed for MEDLINE]Related articles