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    Results: 1 to 20 of 1169

    1.

    Reversal of streptozotocin-induced diabetes in mice by cellular transduction with recombinant pancreatic transcription factor pancreatic duodenal homeobox-1: a novel protein transduction domain-based therapy.

    Koya V, Lu S, Sun YP, Purich DL, Atkinson MA, Li SW, Yang LJ.

    Diabetes. 2008 Mar;57(3):757-69. Epub 2007 Dec 17.PMID: 18086901 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Adult rat liver cells transdifferentiated with lentiviral IPF1 vectors reverse diabetes in mice: an ex vivo gene therapy approach.

    Fodor A, Harel C, Fodor L, Armoni M, Salmon P, Trono D, Karnieli E.

    Diabetologia. 2007 Jan;50(1):121-30. Epub 2006 Nov 28.PMID: 17131142 [PubMed - indexed for MEDLINE]Related articles

    3.

    Reversal of streptozotocin-induced diabetes in rats by gene therapy with betacellulin and pancreatic duodenal homeobox-1.

    Chen S, Ding J, Yu C, Yang B, Wood DR, Grayburn PA.

    Gene Ther. 2007 Jul;14(14):1102-10. Epub 2007 Apr 26.PMID: 17460716 [PubMed - indexed for MEDLINE]Related articles

    4.

    Reprogramming liver-stem WB cells into functional insulin-producing cells by persistent expression of Pdx1- and Pdx1-VP16 mediated by lentiviral vectors.

    Tang DQ, Lu S, Sun YP, Rodrigues E, Chou W, Yang C, Cao LZ, Chang LJ, Yang LJ.

    Lab Invest. 2006 Jan;86(1):83-93.PMID: 16294197 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Role of oxidative stress in pancreatic beta-cell dysfunction.

    Kajimoto Y, Kaneto H.

    Ann N Y Acad Sci. 2004 Apr;1011:168-76.PMID: 15126294 [PubMed - indexed for MEDLINE]Related articles

    6.

    Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia.

    Ferber S, Halkin A, Cohen H, Ber I, Einav Y, Goldberg I, Barshack I, Seijffers R, Kopolovic J, Kaiser N, Karasik A.

    Nat Med. 2000 May;6(5):568-72.PMID: 10802714 [PubMed - indexed for MEDLINE]Related articles

    7.

    Role of Pax4 in Pdx1-VP16-mediated liver-to-endocrine pancreas transdifferentiation.

    Tang DQ, Cao LZ, Chou W, Shun L, Farag C, Atkinson MA, Li SW, Chang LJ, Yang LJ.

    Lab Invest. 2006 Aug;86(8):829-41. Epub 2006 May 29.PMID: 16732298 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats.

    Perfetti R, Zhou J, Doyle ME, Egan JM.

    Endocrinology. 2000 Dec;141(12):4600-5.PMID: 11108273 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Adenovirus transduction is required for the correction of diabetes using Pdx-1 or Neurogenin-3 in the liver.

    Wang AY, Ehrhardt A, Xu H, Kay MA.

    Mol Ther. 2007 Feb;15(2):255-63.PMID: 17235302 [PubMed - indexed for MEDLINE]Related articles

    10.

    Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas.

    Holland AM, Góñez LJ, Naselli G, Macdonald RJ, Harrison LC.

    Diabetes. 2005 Sep;54(9):2586-95.PMID: 16123346 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Regulatory regions driving developmental and tissue-specific expression of the essential pancreatic gene pdx1.

    Gannon M, Gamer LW, Wright CV.

    Dev Biol. 2001 Oct 1;238(1):185-201.PMID: 11784003 [PubMed - indexed for MEDLINE]Related articles

    12.

    Insulin-producing cells derived from human pancreatic non-endocrine cell cultures reverse streptozotocin-induced hyperglycaemia in mice.

    Zhao M, Amiel SA, Christie MR, Rela M, Heaton N, Huang GC.

    Diabetologia. 2005 Oct;48(10):2051-61. Epub 2005 Aug 17.PMID: 16132961 [PubMed - indexed for MEDLINE]Related articles

    13.

    Directed differentiation of human embryonic stem cells towards a pancreatic cell fate.

    Shim JH, Kim SE, Woo DH, Kim SK, Oh CH, McKay R, Kim JH.

    Diabetologia. 2007 Jun;50(6):1228-38. Epub 2007 Apr 18.PMID: 17457565 [PubMed - indexed for MEDLINE]Related articles

    14.

    The homeodomain-interacting protein kinase 2 regulates insulin promoter factor-1/pancreatic duodenal homeobox-1 transcriptional activity.

    Boucher MJ, Simoneau M, Edlund H.

    Endocrinology. 2009 Jan;150(1):87-97. Epub 2008 Sep 4.PMID: 18772243 [PubMed - indexed for MEDLINE]Related articles

    15.

    beta-Cell Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1.

    Li Y, Cao X, Li LX, Brubaker PL, Edlund H, Drucker DJ.

    Diabetes. 2005 Feb;54(2):482-91.PMID: 15677506 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Persistent expression of HNF6 in islet endocrine cells causes disrupted islet architecture and loss of beta cell function.

    Gannon M, Ray MK, Van Zee K, Rausa F, Costa RH, Wright CV.

    Development. 2000 Jul;127(13):2883-95.PMID: 10851133 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Silymarin induces recovery of pancreatic function after alloxan damage in rats.

    Soto C, Mena R, Luna J, Cerbón M, Larrieta E, Vital P, Uría E, Sánchez M, Recoba R, Barrón H, Favari L, Lara A.

    Life Sci. 2004 Sep 17;75(18):2167-80.PMID: 15325843 [PubMed - indexed for MEDLINE]Related articles

    18.

    The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth.

    Kitamura T, Nakae J, Kitamura Y, Kido Y, Biggs WH 3rd, Wright CV, White MF, Arden KC, Accili D.

    J Clin Invest. 2002 Dec;110(12):1839-47.PMID: 12488434 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Maturation of adult beta-cells revealed using a Pdx1/insulin dual-reporter lentivirus.

    Szabat M, Luciani DS, Piret JM, Johnson JD.

    Endocrinology. 2009 Apr;150(4):1627-35. Epub 2008 Dec 18.PMID: 19095744 [PubMed - indexed for MEDLINE]Related articles

    20.

    Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus.

    Seufert J, Weir GC, Habener JF.

    J Clin Invest. 1998 Jun 1;101(11):2528-39.PMID: 9616224 [PubMed - indexed for MEDLINE]Related articlesFree article

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