PubMed

Different brain responses to hypoglycemia induced by equipotent doses of the long-acting insulin analog detemir and human regular insulin in humans.

Rossetti P, Porcellati F, Ricci NB, Candeloro P, Cioli P, Bolli GB, Fanelli CG.

Diabetes. 2008 Mar;57(3):746-56. Epub 2007 Dec 14.PMID: 18083783 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced counterregulation during hypoglycemia with raised circulating nonglucose lipid substrates: evidence for regional differences in metabolic capacity in the human brain?

Evans ML, Matyka K, Lomas J, Pernet A, Cranston IC, Macdonald I, Amiel SA.

J Clin Endocrinol Metab. 1998 Aug;83(8):2952-9.PMID: 9709975 [PubMed - indexed for MEDLINE]Related articlesFree article

Short-term effects of the long-acting insulin analog detemir and human insulin on plasma levels of insulin-like growth factor-I and its binding proteins in humans.

Porcellati F, Rossetti P, Candeloro P, Lucidi P, Cioli P, Andreoli AM, Ghigo E, Bolli GB, Fanelli CG.

J Clin Endocrinol Metab. 2009 Aug;94(8):3017-24. Epub 2009 May 26.PMID: 19470629 [PubMed - indexed for MEDLINE]Related articles

Glycemic thresholds for activation of glucose counterregulatory systems are higher than the threshold for symptoms.

Schwartz NS, Clutter WE, Shah SD, Cryer PE.

J Clin Invest. 1987 Mar;79(3):777-81.PMID: 3546378 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of antecedent hypoglycemia on cognitive function and on glycemic thresholds for counterregulatory hormone secretion in healthy humans.

Mellman MJ, Davis MR, Brisman M, Shamoon H.

Diabetes Care. 1994 Mar;17(3):183-8.PMID: 8174445 [PubMed - indexed for MEDLINE]Related articles

Differential gender responses to hypoglycemia are due to alterations in CNS drive and not glycemic thresholds.

Davis SN, Shavers C, Costa F.

Am J Physiol Endocrinol Metab. 2000 Nov;279(5):E1054-63.PMID: 11052960 [PubMed - indexed for MEDLINE]Related articlesFree article

Counterregulatory response to hypoglycemia differs according to the insulin delivery route, but does not affect glucose production in normal humans.

Lewis GF, Carpentier A, Bilinski D, Giacca A, Vranic M.

J Clin Endocrinol Metab. 1999 Mar;84(3):1037-46.PMID: 10084592 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of recent, short-term hyperglycemia on responses to hypoglycemia in humans. Relevance to the pathogenesis of hypoglycemia unawareness and hyperglycemia-induced insulin resistance.

Fanelli C, Pampanelli S, Calderone S, Lepore M, Annibale B, Compagnucci P, Brunetti P, Bolli GB.

Diabetes. 1995 May;44(5):513-9.PMID: 7729608 [PubMed - indexed for MEDLINE]Related articles

Mechanism of awareness of hypoglycemia. Perception of neurogenic (predominantly cholinergic) rather than neuroglycopenic symptoms.

Towler DA, Havlin CE, Craft S, Cryer P.

Diabetes. 1993 Dec;42(12):1791-8.PMID: 8243825 [PubMed - indexed for MEDLINE]Related articles

Long-term intensive insulin therapy in IDDM: effects on HbA1c, risk for severe and mild hypoglycaemia, status of counterregulation and awareness of hypoglycaemia.

Pampanelli S, Fanelli C, Lalli C, Ciofetta M, Sindaco PD, Lepore M, Modarelli F, Rambotti AM, Epifano L, Di Vincenzo A, Bartocci L, Annibale B, Brunetti P, Bolli GB.

Diabetologia. 1996 Jun;39(6):677-86.PMID: 8781763 [PubMed - indexed for MEDLINE]Related articles

Impact of recent antecedent hypoglycemia on hypoglycemic cognitive dysfunction in nondiabetic humans.

Hvidberg A, Fanelli CG, Hershey T, Terkamp C, Craft S, Cryer PE.

Diabetes. 1996 Aug;45(8):1030-6.PMID: 8690148 [PubMed - indexed for MEDLINE]Related articles

Sexual dimorphism in counterregulatory responses to hypoglycemia after antecedent exercise.

Galassetti P, Neill AR, Tate D, Ertl AC, Wasserman DH, Davis SN.

J Clin Endocrinol Metab. 2001 Aug;86(8):3516-24.PMID: 11502773 [PubMed - indexed for MEDLINE]Related articlesFree article

Post-hypoglycaemic hyperketonaemia does not contribute to brain metabolism during insulin-induced hypoglycaemia in humans.

Fanelli C, Di Vincenzo A, Modarelli F, Lepore M, Ciofetta M, Epifano L, Pampanelli S, Brunetti P, Bolli GB.

Diabetologia. 1993 Nov;36(11):1191-7.PMID: 8270135 [PubMed - indexed for MEDLINE]Related articles

Effect of near physiologic insulin therapy on hypoglycemia counterregulation in type-1 diabetes.

Bischof MG, Bernroider E, Ludwig C, Kurzemann S, Kletter K, Waldhäusl W, Roden M.

Horm Res. 2001;56(5-6):151-8.PMID: 11910200 [PubMed - indexed for MEDLINE]Related articles

Reduced beta-adrenergic sensitivity in patients with type 1 diabetes and hypoglycemia unawareness.

Korytkowski MT, Mokan M, Veneman TF, Mitrakou A, Cryer PE, Gerich JE.

Diabetes Care. 1998 Nov;21(11):1939-43.PMID: 9802747 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of antecedent prolonged exercise on subsequent counterregulatory responses to hypoglycemia.

Galassetti P, Mann S, Tate D, Neill RA, Costa F, Wasserman DH, Davis SN.

Am J Physiol Endocrinol Metab. 2001 Jun;280(6):E908-17.PMID: 11350772 [PubMed - indexed for MEDLINE]Related articlesFree article

A double-blind, randomized, dose-response study investigating the pharmacodynamic and pharmacokinetic properties of the long-acting insulin analog detemir.

Plank J, Bodenlenz M, Sinner F, Magnes C, Görzer E, Regittnig W, Endahl LA, Draeger E, Zdravkovic M, Pieber TR.

Diabetes Care. 2005 May;28(5):1107-12.PMID: 15855574 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term intensive therapy of IDDM patients with clinically overt autonomic neuropathy: effects on hypoglycemia awareness and counterregulation.

Fanelli C, Pampanelli S, Lalli C, Del Sindaco P, Ciofetta M, Lepore M, Porcellati F, Bottini P, Di Vincenzo A, Brunetti P, Bolli GB.

Diabetes. 1997 Jul;46(7):1172-81.PMID: 9200653 [PubMed - indexed for MEDLINE]Related articles

Comparison of pharmacokinetics and dynamics of the long-acting insulin analogs glargine and detemir at steady state in type 1 diabetes: a double-blind, randomized, crossover study.

Porcellati F, Rossetti P, Busciantella NR, Marzotti S, Lucidi P, Luzio S, Owens DR, Bolli GB, Fanelli CG.

Diabetes Care. 2007 Oct;30(10):2447-52. Epub 2007 Jul 10. Erratum in: Diabetes Care. 2008 Jan;31(1):188. PMID: 17623819 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of glucose counterregulation during short-term and prolonged hypoglycemia in normal humans.

De Feo P, Perriello G, De Cosmo S, Ventura MM, Campbell PJ, Brunetti P, Gerich JE, Bolli GB.

Diabetes. 1986 May;35(5):563-9.PMID: 2869997 [PubMed - indexed for MEDLINE]Related articles