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    Results: 1 to 20 of 542

    1.

    Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes.

    Curtis C, Landis GN, Folk D, Wehr NB, Hoe N, Waskar M, Abdueva D, Skvortsov D, Ford D, Luu A, Badrinath A, Levine RL, Bradley TJ, Tavaré S, Tower J.

    Genome Biol. 2007;8(12):R262.

    PMID:
    18067683
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Testing an 'aging gene' in long-lived drosophila strains: increased longevity depends on sex and genetic background.

    Spencer CC, Howell CE, Wright AR, Promislow DE.

    Aging Cell. 2003 Apr;2(2):123-30.

    PMID:
    12882325
    [PubMed - indexed for MEDLINE]
    3.

    Evolutionary conservation of regulated longevity assurance mechanisms.

    McElwee JJ, Schuster E, Blanc E, Piper MD, Thomas JH, Patel DS, Selman C, Withers DJ, Thornton JM, Partridge L, Gems D.

    Genome Biol. 2007;8(7):R132.

    PMID:
    17612391
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans.

    Van Raamsdonk JM, Hekimi S.

    PLoS Genet. 2009 Feb;5(2):e1000361. Epub 2009 Feb 6.

    PMID:
    19197346
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    5.

    Modulation of longevity and diapause by redox regulation mechanisms under the insulin-like signaling control in Caenorhabditis elegans.

    Honda Y, Tanaka M, Honda S.

    Exp Gerontol. 2008 Jun;43(6):520-9. Epub 2008 Mar 18.

    PMID:
    18406553
    [PubMed - indexed for MEDLINE]
    6.

    Effects of sod gene overexpression and deletion mutation on the expression profiles of reporter genes of major detoxification pathways in Caenorhabditis elegans.

    Back P, Matthijssens F, Vlaeminck C, Braeckman BP, Vanfleteren JR.

    Exp Gerontol. 2010 Aug;45(7-8):603-10. Epub 2010 Jan 22.

    PMID:
    20096764
    [PubMed - indexed for MEDLINE]
    7.

    Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance.

    McElwee JJ, Schuster E, Blanc E, Thomas JH, Gems D.

    J Biol Chem. 2004 Oct 22;279(43):44533-43. Epub 2004 Aug 11.

    PMID:
    15308663
    [PubMed - indexed for MEDLINE]
    Free Article
    8.

    Redox regulation, gene expression and longevity.

    Honda Y, Tanaka M, Honda S.

    Geriatr Gerontol Int. 2010 Jul;10 Suppl 1:S59-69.

    PMID:
    20590843
    [PubMed - indexed for MEDLINE]
    9.

    Dynamics of the action of dFOXO on adult mortality in Drosophila.

    Giannakou ME, Goss M, Jacobson J, Vinti G, Leevers SJ, Partridge L.

    Aging Cell. 2007 Aug;6(4):429-38. Epub 2007 Apr 26.

    PMID:
    17465980
    [PubMed - indexed for MEDLINE]
    11.

    Drosophila germ-line modulation of insulin signaling and lifespan.

    Flatt T, Min KJ, D'Alterio C, Villa-Cuesta E, Cumbers J, Lehmann R, Jones DL, Tatar M.

    Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6368-73. Epub 2008 Apr 23.

    PMID:
    18434551
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    12.

    Drosophila lifespan control by dietary restriction independent of insulin-like signaling.

    Min KJ, Yamamoto R, Buch S, Pankratz M, Tatar M.

    Aging Cell. 2008 Mar;7(2):199-206. Epub 2008 Jan 21.

    PMID:
    18221413
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    13.

    The determinants of lifespan in the nematode Caenorhabditis elegans: a short primer.

    Geanacopoulos M.

    Sci Prog. 2004;87(Pt 4):227-47. Review.

    PMID:
    16028834
    [PubMed - indexed for MEDLINE]
    14.

    Decreased expression of Cu-Zn superoxide dismutase 1 in ants with extreme lifespan.

    Parker JD, Parker KM, Sohal BH, Sohal RS, Keller L.

    Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3486-9. Epub 2004 Mar 1.

    PMID:
    14993600
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    15.

    The search for DAF-16/FOXO transcriptional targets: approaches and discoveries.

    Murphy CT.

    Exp Gerontol. 2006 Oct;41(10):910-21. Epub 2006 Aug 24. Review.

    PMID:
    16934425
    [PubMed - indexed for MEDLINE]
    16.

    Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk.

    Slack C, Werz C, Wieser D, Alic N, Foley A, Stocker H, Withers DJ, Thornton JM, Hafen E, Partridge L.

    PLoS Genet. 2010 Mar 19;6(3):e1000881.

    PMID:
    20333234
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    17.

    Insulin/IGF-like signalling, the central nervous system and aging.

    Broughton S, Partridge L.

    Biochem J. 2009 Feb 15;418(1):1-12. Review.

    PMID:
    19159343
    [PubMed - indexed for MEDLINE]
    18.

    Gene expression profiling implicates OXPHOS complexes in lifespan extension of flies over-expressing a small mitochondrial chaperone, Hsp22.

    Kim HJ, Morrow G, Westwood JT, Michaud S, Tanguay RM.

    Exp Gerontol. 2010 Aug;45(7-8):611-20. Epub 2009 Dec 29.

    PMID:
    20036725
    [PubMed - indexed for MEDLINE]
    19.

    A transcription elongation factor that links signals from the reproductive system to lifespan extension in Caenorhabditis elegans.

    Ghazi A, Henis-Korenblit S, Kenyon C.

    PLoS Genet. 2009 Sep;5(9):e1000639. Epub 2009 Sep 11.

    PMID:
    19749979
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    20.

    Targeted neuronal gene expression and longevity in Drosophila.

    Phillips JP, Parkes TL, Hilliker AJ.

    Exp Gerontol. 2000 Dec;35(9-10):1157-64.

    PMID:
    11113599
    [PubMed - indexed for MEDLINE]

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