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    Results: 1 to 20 of 248

    1.

    The repression of IRS2 gene by ATF3, a stress-inducible gene, contributes to pancreatic beta-cell apoptosis.

    Li D, Yin X, Zmuda EJ, Wolford CC, Dong X, White MF, Hai T.

    Diabetes. 2008 Mar;57(3):635-44. Epub 2007 Dec 5.PMID: 18057093 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function.

    Park S, Dong X, Fisher TL, Dunn S, Omer AK, Weir G, White MF.

    J Biol Chem. 2006 Jan 13;281(2):1159-68. Epub 2005 Nov 4.PMID: 16272563 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Exercise improves glucose homeostasis that has been impaired by a high-fat diet by potentiating pancreatic beta-cell function and mass through IRS2 in diabetic rats.

    Park S, Hong SM, Lee JE, Sung SR.

    J Appl Physiol. 2007 Nov;103(5):1764-71. Epub 2007 Aug 30.PMID: 17761790 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Role for activating transcription factor 3 in stress-induced beta-cell apoptosis.

    Hartman MG, Lu D, Kim ML, Kociba GJ, Shukri T, Buteau J, Wang X, Frankel WL, Guttridge D, Prentki M, Grey ST, Ron D, Hai T.

    Mol Cell Biol. 2004 Jul;24(13):5721-32.PMID: 15199129 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes.

    Hennige AM, Burks DJ, Ozcan U, Kulkarni RN, Ye J, Park S, Schubert M, Fisher TL, Dow MA, Leshan R, Zakaria M, Mossa-Basha M, White MF.

    J Clin Invest. 2003 Nov;112(10):1521-32.PMID: 14617753 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human beta-cells from hyperglycemia-induced apoptosis.

    Mohanty S, Spinas GA, Maedler K, Zuellig RA, Lehmann R, Donath MY, Trüb T, Niessen M.

    Exp Cell Res. 2005 Feb 1;303(1):68-78.PMID: 15572028 [PubMed - indexed for MEDLINE]Related articles

    7.

    Role of activating transcription factor 3 on TAp73 stability and apoptosis in paclitaxel-treated cervical cancer cells.

    Oh YK, Lee HJ, Jeong MH, Rhee M, Mo JW, Song EH, Lim JY, Choi KH, Jo I, Park SI, Gao B, Kwon Y, Kim WH.

    Mol Cancer Res. 2008 Jul;6(7):1232-49.PMID: 18644986 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Phosphatase and tensin homolog regulation of islet growth and glucose homeostasis.

    Kushner JA, Simpson L, Wartschow LM, Guo S, Rankin MM, Parsons R, White MF.

    J Biol Chem. 2005 Nov 25;280(47):39388-93. Epub 2005 Sep 16.PMID: 16170201 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling.

    Guo S, Dunn SL, White MF.

    Mol Endocrinol. 2006 Dec;20(12):3389-99. Epub 2006 Aug 17.PMID: 16916938 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Pdx1 expression in Irs2-deficient mouse beta-cells is regulated in a strain-dependent manner.

    Suzuki R, Tobe K, Terauchi Y, Komeda K, Kubota N, Eto K, Yamauchi T, Azuma K, Kaneto H, Taguchi T, Koga T, German MS, Watada H, Kawamori R, Wright CV, Kajimoto Y, Kimura S, Nagai R, Kadowaki T.

    J Biol Chem. 2003 Oct 31;278(44):43691-8. Epub 2003 Jul 16.PMID: 12869553 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Transcriptional repressor activating transcription factor 3 protects human umbilical vein endothelial cells from tumor necrosis factor-alpha-induced apoptosis through down-regulation of p53 transcription.

    Kawauchi J, Zhang C, Nobori K, Hashimoto Y, Adachi MT, Noda A, Sunamori M, Kitajima S.

    J Biol Chem. 2002 Oct 11;277(41):39025-34. Epub 2002 Aug 2.PMID: 12161427 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Beta cell-specific deficiency of the stimulatory G protein alpha-subunit Gsalpha leads to reduced beta cell mass and insulin-deficient diabetes.

    Xie T, Chen M, Zhang QH, Ma Z, Weinstein LS.

    Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19601-6. Epub 2007 Nov 20.PMID: 18029451 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Pdx1 restores beta cell function in Irs2 knockout mice.

    Kushner JA, Ye J, Schubert M, Burks DJ, Dow MA, Flint CL, Dutta S, Wright CV, Montminy MR, White MF.

    J Clin Invest. 2002 May;109(9):1193-201.PMID: 11994408 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival.

    Podcheko A, Northcott P, Bikopoulos G, Lee A, Bommareddi SR, Kushner JA, Farhang-Fallah J, Rozakis-Adcock M.

    Mol Cell Biol. 2007 Sep;27(18):6484-96. Epub 2007 Jul 16.PMID: 17636024 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus.

    Kubota N, Terauchi Y, Tobe K, Yano W, Suzuki R, Ueki K, Takamoto I, Satoh H, Maki T, Kubota T, Moroi M, Okada-Iwabu M, Ezaki O, Nagai R, Ueta Y, Kadowaki T, Noda T.

    J Clin Invest. 2004 Oct;114(7):917-27.PMID: 15467830 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.

    Jhala US, Canettieri G, Screaton RA, Kulkarni RN, Krajewski S, Reed J, Walker J, Lin X, White M, Montminy M.

    Genes Dev. 2003 Jul 1;17(13):1575-80.PMID: 12842910 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    On the role of IRS2 in the regulation of functional beta-cell mass.

    Niessen M.

    Arch Physiol Biochem. 2006 Apr;112(2):65-73. Review.PMID: 16931448 [PubMed - indexed for MEDLINE]Related articles

    18.

    The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth.

    Kitamura T, Nakae J, Kitamura Y, Kido Y, Biggs WH 3rd, Wright CV, White MF, Arden KC, Accili D.

    J Clin Invest. 2002 Dec;110(12):1839-47.PMID: 12488434 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Transgenic expression of insulin receptor substrate 2 in murine B cells alters the cell density-dependence of IgE production in vitro and enhances IgE production in vivo.

    Kelly-Welch AE, Wang HY, Wang LM, Pierce JH, Jay G, Finkelman F, Keegan AD.

    J Immunol. 2004 Mar 1;172(5):2803-10.PMID: 14978080 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Activating transcription factor 3, a stress-inducible gene, suppresses Ras-stimulated tumorigenesis.

    Lu D, Wolfgang CD, Hai T.

    J Biol Chem. 2006 Apr 14;281(15):10473-81. Epub 2006 Feb 9.PMID: 16469745 [PubMed - indexed for MEDLINE]Related articlesFree article

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