Warning: The NCBI web site requires JavaScript to function. more...
Using protein complexes to predict phenotypic effects of gene mutation.
Fraser HB, Plotkin JB.
Genome Biol. 2007;8(11):R252.
Related citations
Modelling genotype-phenotype relationships and human disease with genetic interaction networks.
Lehner B.
J Exp Biol. 2007 May;210(Pt 9):1559-66. Review.
Network hubs buffer environmental variation in Saccharomyces cerevisiae.
Levy SF, Siegal ML.
PLoS Biol. 2008 Nov 4;6(11):e264.
Conserved co-expression for candidate disease gene prioritization.
Oti M, van Reeuwijk J, Huynen MA, Brunner HG.
BMC Bioinformatics. 2008 Apr 23;9:208.
Approaches to identify genes for complex human diseases: lessons from Mendelian disorders.
Dean M.
Hum Mutat. 2003 Oct;22(4):261-74. Review.
Predicting genetic modifier loci using functional gene networks.
Lee I, Lehner B, Vavouri T, Shin J, Fraser AG, Marcotte EM.
Genome Res. 2010 Aug;20(8):1143-53. Epub 2010 Jun 9.
A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans.
Lee I, Lehner B, Crombie C, Wong W, Fraser AG, Marcotte EM.
Nat Genet. 2008 Feb;40(2):181-8. Epub 2008 Jan 27.
Information flow analysis of interactome networks.
Missiuro PV, Liu K, Zou L, Ross BC, Zhao G, Liu JS, Ge H.
PLoS Comput Biol. 2009 Apr;5(4):e1000350. Epub 2009 Apr 10.
Mutations in genes involved in nonsense mediated decay ameliorate the phenotype of sel-12 mutants with amber stop mutations in Caenorhabditis elegans.
Gontijo AM, Aubert S, Roelens I, Lakowski B.
BMC Genet. 2009 Mar 20;10:14.
Predicting quantitative genetic interactions by means of sequential matrix approximation.
Järvinen AP, Hiissa J, Elo LL, Aittokallio T.
PLoS One. 2008 Sep 26;3(9):e3284.
Predicting phenotypic effects of gene perturbations in C. elegans using an integrated network model.
Borgwardt K.
Bioessays. 2008 Aug;30(8):707-10. Review.
Destabilizing protein polymorphisms in the genetic background direct phenotypic expression of mutant SOD1 toxicity.
Gidalevitz T, Krupinski T, Garcia S, Morimoto RI.
PLoS Genet. 2009 Mar;5(3):e1000399. Epub 2009 Mar 6.
C. elegans dss-1 is functionally conserved and required for oogenesis and larval growth.
Pispa J, Palmén S, Holmberg CI, Jäntti J.
BMC Dev Biol. 2008 May 9;8:51.
A text-mining analysis of the human phenome.
van Driel MA, Bruggeman J, Vriend G, Brunner HG, Leunissen JA.
Eur J Hum Genet. 2006 May;14(5):535-42.
Identification and characterization of protein subcomplexes in yeast.
Hollunder J, Beyer A, Wilhelm T.
Proteomics. 2005 May;5(8):2082-9.
Complex topology rather than complex membership is a determinant of protein dosage sensitivity.
Oberdorf R, Kortemme T.
Mol Syst Biol. 2009;5:253. Epub 2009 Mar 17.
Evolutionary plasticity of genetic interaction networks.
Tischler J, Lehner B, Fraser AG.
Nat Genet. 2008 Apr;40(4):390-1. Epub 2008 Mar 23.
Derivation of genetic interaction networks from quantitative phenotype data.
Drees BL, Thorsson V, Carter GW, Rives AW, Raymond MZ, Avila-Campillo I, Shannon P, Galitski T.
Genome Biol. 2005;6(4):R38. Epub 2005 Mar 31.
Functional genomics approaches to neurodegenerative diseases.
Rubinsztein DC.
Mamm Genome. 2008 Sep;19(9):587-90. Epub 2008 Jul 30. Review.
Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens.
Yin Z, Zhou X, Bakal C, Li F, Sun Y, Perrimon N, Wong ST.
BMC Bioinformatics. 2008 Jun 5;9:264.
Filter your results:
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on