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    Results: 1 to 20 of 350

    1.

    Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator-alpha and DUSP14.

    Klinger S, Poussin C, Debril MB, Dolci W, Halban PA, Thorens B.

    Diabetes. 2008 Mar;57(3):584-93. Epub 2007 Nov 19.PMID: 18025410 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Exendin-4 induction of cyclin D1 expression in INS-1 beta-cells: involvement of cAMP-responsive element.

    Kim MJ, Kang JH, Park YG, Ryu GR, Ko SH, Jeong IK, Koh KH, Rhie DJ, Yoon SH, Hahn SJ, Kim MS, Jo YH.

    J Endocrinol. 2006 Mar;188(3):623-33.PMID: 16522741 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.

    Granata R, Settanni F, Gallo D, Trovato L, Biancone L, Cantaluppi V, Nano R, Annunziata M, Campiglia P, Arnoletti E, Ghè C, Volante M, Papotti M, Muccioli G, Ghigo E.

    Diabetes. 2008 Apr;57(4):967-79. Epub 2007 Dec 27.PMID: 18162507 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation.

    Liu Z, Habener JF.

    J Biol Chem. 2008 Mar 28;283(13):8723-35. Epub 2008 Jan 23.PMID: 18216022 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways.

    Friedrichsen BN, Neubauer N, Lee YC, Gram VK, Blume N, Petersen JS, Nielsen JH, Møldrup A.

    J Endocrinol. 2006 Mar;188(3):481-92.PMID: 16522728 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Synergistic effect of dimethyl sulfoxide on glucagon-like peptide 1 (GLP-1)-stimulated insulin secretion and gene transcription in INS-1 cells: characterization and implications.

    Kemp DM, Habener JF.

    Biochem Pharmacol. 2002 Aug 15;64(4):689-97.PMID: 12167488 [PubMed - indexed for MEDLINE]Related articles

    7.

    Anti-proliferative effect of pro-inflammatory cytokines in cultured beta cells is associated with extracellular signal-regulated kinase 1/2 pathway inhibition: protective role of glucagon-like peptide -1.

    Blandino-Rosano M, Perez-Arana G, Mellado-Gil JM, Segundo C, Aguilar-Diosdado M.

    J Mol Endocrinol. 2008 Jul;41(1):35-44. Epub 2008 May 16.PMID: 18487229 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Identification of glucagon-like peptide-2 (GLP-2)-activated signaling pathways in baby hamster kidney fibroblasts expressing the rat GLP-2 receptor.

    Yusta B, Somwar R, Wang F, Munroe D, Grinstein S, Klip A, Drucker DJ.

    J Biol Chem. 1999 Oct 22;274(43):30459-67.PMID: 10521425 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Exendin-4 stimulation of cyclin A2 in beta-cell proliferation.

    Song WJ, Schreiber WE, Zhong E, Liu FF, Kornfeld BD, Wondisford FE, Hussain MA.

    Diabetes. 2008 Sep;57(9):2371-81. Epub 2008 Jun 10.PMID: 18544709 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Mechanisms of glucose-induced expression of pancreatic-derived factor in pancreatic beta-cells.

    Wang O, Cai K, Pang S, Wang T, Qi D, Zhu Q, Ni Z, Le Y.

    Endocrinology. 2008 Feb;149(2):672-80. Epub 2007 Oct 25.PMID: 17962352 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Glucagon-like peptide 1 induces pancreatic beta-cell proliferation via transactivation of the epidermal growth factor receptor.

    Buteau J, Foisy S, Joly E, Prentki M.

    Diabetes. 2003 Jan;52(1):124-32.PMID: 12502502 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3',5'-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-Kinase/Akt signaling.

    Granata R, Settanni F, Biancone L, Trovato L, Nano R, Bertuzzi F, Destefanis S, Annunziata M, Martinetti M, Catapano F, Ghè C, Isgaard J, Papotti M, Ghigo E, Muccioli G.

    Endocrinology. 2007 Feb;148(2):512-29. Epub 2006 Oct 26.PMID: 17068144 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation.

    Buteau J, Foisy S, Rhodes CJ, Carpenter L, Biden TJ, Prentki M.

    Diabetes. 2001 Oct;50(10):2237-43.PMID: 11574404 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop.

    Cornu M, Yang JY, Jaccard E, Poussin C, Widmann C, Thorens B.

    Diabetes. 2009 Aug;58(8):1816-25. Epub 2009 Apr 28.PMID: 19401425 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Degradation of cAMP-responsive element-binding protein by the ubiquitin-proteasome pathway contributes to glucotoxicity in beta-cells and human pancreatic islets.

    Costes S, Vandewalle B, Tourrel-Cuzin C, Broca C, Linck N, Bertrand G, Kerr-Conte J, Portha B, Pattou F, Bockaert J, Dalle S.

    Diabetes. 2009 May;58(5):1105-15. Epub 2009 Feb 17.PMID: 19223597 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Increased pancreatic beta-cell proliferation mediated by CREB binding protein gene activation.

    Hussain MA, Porras DL, Rowe MH, West JR, Song WJ, Schreiber WE, Wondisford FE.

    Mol Cell Biol. 2006 Oct;26(20):7747-59. Epub 2006 Aug 14.PMID: 16908541 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway.

    Ferdaoussi M, Abdelli S, Yang JY, Cornu M, Niederhauser G, Favre D, Widmann C, Regazzi R, Thorens B, Waeber G, Abderrahmani A.

    Diabetes. 2008 May;57(5):1205-15. Epub 2008 Feb 5.PMID: 18252896 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Inhibition of membrane depolarisation-induced transcriptional activity of cyclic AMP response element binding protein (CREB) by the dual-leucine-zipper-bearing kinase in a pancreatic islet beta cell line.

    Oetjen E, Lechleiter A, Blume R, Nihalani D, Holzman L, Knepel W.

    Diabetologia. 2006 Feb;49(2):332-42. Epub 2005 Dec 21.PMID: 16369771 [PubMed - indexed for MEDLINE]Related articles

    19.

    The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1.

    Brun T, He KH, Lupi R, Boehm B, Wojtusciszyn A, Sauter N, Donath M, Marchetti P, Maedler K, Gauthier BR.

    Hum Mol Genet. 2008 Feb 15;17(4):478-89. Epub 2007 Nov 7.PMID: 17989064 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Beta-Arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic beta cells.

    Sonoda N, Imamura T, Yoshizaki T, Babendure JL, Lu JC, Olefsky JM.

    Proc Natl Acad Sci U S A. 2008 May 6;105(18):6614-9. Epub 2008 Apr 29.PMID: 18445652 [PubMed - indexed for MEDLINE]Related articlesFree article

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