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    Results: 1 to 20 of 550

    1.

    Functional evolution of the vitamin D and pregnane X receptors.

    Reschly EJ, Bainy AC, Mattos JJ, Hagey LR, Bahary N, Mada SR, Ou J, Venkataramanan R, Krasowski MD.

    BMC Evol Biol. 2007 Nov 12;7:222.PMID: 17997857 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Evolution of pharmacologic specificity in the pregnane X receptor.

    Ekins S, Reschly EJ, Hagey LR, Krasowski MD.

    BMC Evol Biol. 2008 Apr 2;8:103.PMID: 18384689 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Evolution of the pregnane x receptor: adaptation to cross-species differences in biliary bile salts.

    Krasowski MD, Yasuda K, Hagey LR, Schuetz EG.

    Mol Endocrinol. 2005 Jul;19(7):1720-39. Epub 2005 Feb 17.PMID: 15718292 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Cloning of a functional vitamin D receptor from the lamprey (Petromyzon marinus), an ancient vertebrate lacking a calcified skeleton and teeth.

    Whitfield GK, Dang HT, Schluter SF, Bernstein RM, Bunag T, Manzon LA, Hsieh G, Dominguez CE, Youson JH, Haussler MR, Marchalonis JJ.

    Endocrinology. 2003 Jun;144(6):2704-16.PMID: 12746335 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors.

    Moore LB, Maglich JM, McKee DD, Wisely B, Willson TM, Kliewer SA, Lambert MH, Moore JT.

    Mol Endocrinol. 2002 May;16(5):977-86.PMID: 11981033 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Ligand specificity and evolution of liver X receptors.

    Reschly EJ, Ai N, Welsh WJ, Ekins S, Hagey LR, Krasowski MD.

    J Steroid Biochem Mol Biol. 2008 May;110(1-2):83-94. Epub 2008 Mar 10.PMID: 18395439 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.

    Cerveny L, Svecova L, Anzenbacherova E, Vrzal R, Staud F, Dvorak Z, Ulrichova J, Anzenbacher P, Pavek P.

    Drug Metab Dispos. 2007 Jul;35(7):1032-41. Epub 2007 Mar 28.PMID: 17392393 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Evolution of the bile salt nuclear receptor FXR in vertebrates.

    Reschly EJ, Ai N, Ekins S, Welsh WJ, Hagey LR, Hofmann AF, Krasowski MD.

    J Lipid Res. 2008 Jul;49(7):1577-87. Epub 2008 Mar 24.PMID: 18362391 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Induction of cytochrome P450 3A by paclitaxel in mice: pivotal role of the nuclear xenobiotic receptor, pregnane X receptor.

    Nallani SC, Goodwin B, Maglich JM, Buckley DJ, Buckley AR, Desai PB.

    Drug Metab Dispos. 2003 May;31(5):681-4.PMID: 12695359 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor.

    Shenoy SD, Spencer TA, Mercer-Haines NA, Alipour M, Gargano MD, Runge-Morris M, Kocarek TA.

    Drug Metab Dispos. 2004 Jan;32(1):66-71.PMID: 14709622 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.

    Xu DX, Wei W, Sun MF, Wu CY, Wang JP, Wei LZ, Zhou CF.

    Free Radic Biol Med. 2004 Jul 1;37(1):10-22.PMID: 15183191 [PubMed - indexed for MEDLINE]Related articles

    14.

    Regulation of drug transporter gene expression by nuclear receptors.

    Staudinger JL, Madan A, Carol KM, Parkinson A.

    Drug Metab Dispos. 2003 May;31(5):523-7.PMID: 12695338 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    A human and mouse pregnane X receptor reporter gene assay in combination with cytotoxicity measurements as a tool to evaluate species-specific CYP3A induction.

    Vignati LA, Bogni A, Grossi P, Monshouwer M.

    Toxicology. 2004 Jun 1;199(1):23-33.PMID: 15125996 [PubMed - indexed for MEDLINE]Related articles

    16.

    Dehydroepiandrosterone sulfotransferase is a target for transcriptional induction by the vitamin D receptor.

    Echchgadda I, Song CS, Roy AK, Chatterjee B.

    Mol Pharmacol. 2004 Mar;65(3):720-9.PMID: 14978251 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression.

    Svecova L, Vrzal R, Burysek L, Anzenbacherova E, Cerveny L, Grim J, Trejtnar F, Kunes J, Pour M, Staud F, Anzenbacher P, Dvorak Z, Pavek P.

    Drug Metab Dispos. 2008 Feb;36(2):339-48. Epub 2007 Nov 12.PMID: 17998298 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT.

    Kiyosawa N, Kwekel JC, Burgoon LD, Dere E, Williams KJ, Tashiro C, Chittim B, Zacharewski TR.

    BMC Genomics. 2008 Oct 16;9:487.PMID: 18925944 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors.

    Ricketts ML, Boekschoten MV, Kreeft AJ, Hooiveld GJ, Moen CJ, Müller M, Frants RR, Kasanmoentalib S, Post SM, Princen HM, Porter JG, Katan MB, Hofker MH, Moore DD.

    Mol Endocrinol. 2007 Jul;21(7):1603-16. Epub 2007 Apr 24.PMID: 17456796 [PubMed - indexed for MEDLINE]Related articlesFree article

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