PubMed

Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6.

Weaver AM, Silva CM.

Breast Cancer Res. 2007;9(6):R79.PMID: 17997837 [PubMed - indexed for MEDLINE]Related articlesFree article

Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells.

Fox EM, Bernaciak TM, Wen J, Weaver AM, Shupnik MA, Silva CM.

Mol Endocrinol. 2008 Aug;22(8):1781-96. Epub 2008 Jun 11.PMID: 18550772 [PubMed - indexed for MEDLINE]Related articlesFree article

Estrogen negatively regulates epidermal growth factor (EGF)-mediated signal transducer and activator of transcription 5 signaling in human EGF family receptor-overexpressing breast cancer cells.

Boerner JL, Gibson MA, Fox EM, Posner ED, Parsons SJ, Silva CM, Shupnik MA.

Mol Endocrinol. 2005 Nov;19(11):2660-70. Epub 2005 Jun 23.PMID: 15976008 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of signal transducer and activator of transcription 5b activity in breast cancer cells by mutation of tyrosines within the transactivation domain.

Weaver AM, Silva CM.

Mol Endocrinol. 2006 Oct;20(10):2392-405. Epub 2006 Jun 13.PMID: 16772534 [PubMed - indexed for MEDLINE]Related articlesFree article

PRL-induced ERalpha gene expression is mediated by Janus kinase 2 (Jak2) while signal transducer and activator of transcription 5b (Stat5b) phosphorylation involves Jak2 and a second tyrosine kinase.

Frasor J, Barkai U, Zhong L, Fazleabas AT, Gibori G.

Mol Endocrinol. 2001 Nov;15(11):1941-52.PMID: 11682625 [PubMed - indexed for MEDLINE]Related articlesFree article

Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells.

Ostrander JH, Daniel AR, Lofgren K, Kleer CG, Lange CA.

Cancer Res. 2007 May 1;67(9):4199-209.PMID: 17483331 [PubMed - indexed for MEDLINE]Related articlesFree article

Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression.

Lukong KE, Larocque D, Tyner AL, Richard S.

J Biol Chem. 2005 Nov 18;280(46):38639-47. Epub 2005 Sep 22.PMID: 16179349 [PubMed - indexed for MEDLINE]Related articlesFree article

STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor.

Kloth MT, Laughlin KK, Biscardi JS, Boerner JL, Parsons SJ, Silva CM.

J Biol Chem. 2003 Jan 17;278(3):1671-9. Epub 2002 Nov 11.PMID: 12429742 [PubMed - indexed for MEDLINE]Related articlesFree article

S731 in the transactivation domain modulates STAT5b activity.

Weaver AM, Silva CM.

Biochem Biophys Res Commun. 2007 Nov 3;362(4):1026-30. Epub 2007 Aug 28.PMID: 17822672 [PubMed - indexed for MEDLINE]Related articlesFree article

Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b.

Riggins RB, Thomas KS, Ta HQ, Wen J, Davis RJ, Schuh NR, Donelan SS, Owen KA, Gibson MA, Shupnik MA, Silva CM, Parsons SJ, Clarke R, Bouton AH.

Cancer Res. 2006 Jul 15;66(14):7007-15.PMID: 16849545 [PubMed - indexed for MEDLINE]Related articlesFree article

Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion.

Shen CH, Chen HY, Lin MS, Li FY, Chang CC, Kuo ML, Settleman J, Chen RH.

Cancer Res. 2008 Oct 1;68(19):7779-87.PMID: 18829532 [PubMed - indexed for MEDLINE]Related articlesFree article

Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (Stat3) via a Jak- and Src-dependent mechanism in breast cancer cells.

Proietti C, Salatino M, Rosemblit C, Carnevale R, Pecci A, Kornblihtt AR, Molinolo AA, Frahm I, Charreau EH, Schillaci R, Elizalde PV.

Mol Cell Biol. 2005 Jun;25(12):4826-40.PMID: 15923602 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of STAT3 as a specific substrate of breast tumor kinase.

Liu L, Gao Y, Qiu H, Miller WT, Poli V, Reich NC.

Oncogene. 2006 Aug 10;25(35):4904-12. Epub 2006 Mar 27.PMID: 16568091 [PubMed - indexed for MEDLINE]Related articles

BRK phosphorylates PSF promoting its cytoplasmic localization and cell cycle arrest.

Lukong KE, Huot ME, Richard S.

Cell Signal. 2009 Sep;21(9):1415-22. Epub 2009 May 9.PMID: 19439179 [PubMed - indexed for MEDLINE]Related articles

Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin.

Chen HY, Shen CH, Tsai YT, Lin FC, Huang YP, Chen RH.

Mol Cell Biol. 2004 Dec;24(24):10558-72.PMID: 15572663 [PubMed - indexed for MEDLINE]Related articlesFree article

STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation.

Ikeda O, Miyasaka Y, Sekine Y, Mizushima A, Muromoto R, Nanbo A, Yoshimura A, Matsuda T.

Biochem Biophys Res Commun. 2009 Jun 19;384(1):71-5. Epub 2009 Apr 23.PMID: 19393627 [PubMed - indexed for MEDLINE]Related articles

Dual mechanism of signal transducer and activator of transcription 5 activation by the insulin receptor.

Le MN, Kohanski RA, Wang LH, Sadowski HB.

Mol Endocrinol. 2002 Dec;16(12):2764-79.PMID: 12456798 [PubMed - indexed for MEDLINE]Related articlesFree article

Breast tumor kinase BRK requires kinesin-2 subunit KAP3A in modulation of cell migration.

Lukong KE, Richard S.

Cell Signal. 2008 Feb;20(2):432-42. Epub 2007 Nov 13.PMID: 18077133 [PubMed - indexed for MEDLINE]Related articles

Regulated association of protein kinase B/Akt with breast tumor kinase.

Zhang P, Ostrander JH, Faivre EJ, Olsen A, Fitzsimmons D, Lange CA.

J Biol Chem. 2005 Jan 21;280(3):1982-91. Epub 2004 Nov 10.PMID: 15539407 [PubMed - indexed for MEDLINE]Related articlesFree article

Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation.

Schlange T, Matsuda Y, Lienhard S, Huber A, Hynes NE.

Breast Cancer Res. 2007;9(5):R63.PMID: 17897439 [PubMed - indexed for MEDLINE]Related articlesFree article