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    Results: 1 to 20 of 687

    1.

    Long-range enhancers are required to maintain expression of the autoantigen islet-specific glucose-6-phosphatase catalytic subunit-related protein in adult mouse islets in vivo.

    Wang Y, Flemming BP, Martin CC, Allen SR, Walters J, Oeser JK, Hutton JC, O'Brien RM.

    Diabetes. 2008 Jan;57(1):133-41. Epub 2007 Oct 17.PMID: 17942825 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    The proximal islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen promoter is sufficient to initiate but not maintain transgene expression in mouse islets in vivo.

    Frigeri C, Martin CC, Svitek CA, Oeser JK, Hutton JC, Gannon M, O'Brien RM.

    Diabetes. 2004 Jul;53(7):1754-64.PMID: 15220199 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Characterization of the mouse islet-specific glucose-6-phosphatase catalytic subunit-related protein gene promoter by in situ footprinting: correlation with fusion gene expression in the islet-derived betaTC-3 and hamster insulinoma tumor cell lines.

    Bischof LJ, Martin CC, Svitek CA, Stadelmaier BT, Hornbuckle LA, Goldman JK, Oeser JK, Hutton JC, O'Brien RM.

    Diabetes. 2001 Mar;50(3):502-14.PMID: 11246869 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Differential regulation of islet-specific glucose-6-phosphatase catalytic subunit-related protein gene transcription by Pax-6 and Pdx-1.

    Martin CC, Oeser JK, O'Brien RM.

    J Biol Chem. 2004 Aug 13;279(33):34277-89. Epub 2004 Jun 4.PMID: 15180990 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Structure and promoter activity of an islet-specific glucose-6-phosphatase catalytic subunit-related gene.

    Ebert DH, Bischof LJ, Streeper RS, Chapman SC, Svitek CA, Goldman JK, Mathews CE, Leiter EH, Hutton JC, O'Brien RM.

    Diabetes. 1999 Mar;48(3):543-51.PMID: 10078554 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression.

    Martin CC, Flemming BP, Wang Y, Oeser JK, O'Brien RM.

    J Mol Endocrinol. 2008 Nov;41(5):315-28. Epub 2008 Aug 27.PMID: 18753309 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Cloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genes.

    Martin CC, Bischof LJ, Bergman B, Hornbuckle LA, Hilliker C, Frigeri C, Wahl D, Svitek CA, Wong R, Goldman JK, Oeser JK, Leprêtre F, Froguel P, O'Brien RM, Hutton JC.

    J Biol Chem. 2001 Jul 6;276(27):25197-207. Epub 2001 Apr 10.PMID: 11297555 [PubMed - indexed for MEDLINE]Related articles

    9.

    Alternative splicing of G6PC2, the gene coding for the islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP), results in differential expression in human thymus and spleen compared with pancreas.

    Dogra RS, Vaidyanathan P, Prabakar KR, Marshall KE, Hutton JC, Pugliese A.

    Diabetologia. 2006 May;49(5):953-7. Epub 2006 Mar 7.PMID: 16520917 [PubMed - indexed for MEDLINE]Related articles

    10.

    Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein.

    Arden SD, Zahn T, Steegers S, Webb S, Bergman B, O'Brien RM, Hutton JC.

    Diabetes. 1999 Mar;48(3):531-42.PMID: 10078553 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    A 338-bp proximal fragment of the glucose transporter type 2 (GLUT2) promoter drives reporter gene expression in the pancreatic islets of transgenic mice.

    Waeber G, Pedrazzini T, Bonny O, Bonny C, Steinmann M, Nicod P, Haefliger JA.

    Mol Cell Endocrinol. 1995 Oct 30;114(1-2):205-15.PMID: 8674846 [PubMed - indexed for MEDLINE]Related articles

    12.

    Specific targeting of pancreatic islet cells in vivo by insulin-promoter-driven adenoviral conjugated reporter genes.

    Wang X, Olmsted-Davis E, Davis A, Liu S, Li Z, Yang J, Brunicardi FC.

    World J Surg. 2006 Aug;30(8):1543-52.PMID: 16855800 [PubMed - indexed for MEDLINE]Related articles

    13.

    In islet-specific glucose-6-phosphatase-related protein, the beta cell antigenic sequence that is targeted in diabetes is not responsible for the loss of phosphohydrolase activity.

    Shieh JJ, Pan CJ, Mansfield BC, Chou JY.

    Diabetologia. 2005 Sep;48(9):1851-9. Epub 2005 Jul 13.PMID: 16012821 [PubMed - indexed for MEDLINE]Related articles

    14.

    Enzymatic characterization of the pancreatic islet-specific glucose-6-phosphatase-related protein (IGRP).

    Petrolonis AJ, Yang Q, Tummino PJ, Fish SM, Prack AE, Jain S, Parsons TF, Li P, Dales NA, Ge L, Langston SP, Schuller AG, An WF, Tartaglia LA, Chen H, Hong SB.

    J Biol Chem. 2004 Apr 2;279(14):13976-83. Epub 2004 Jan 13.PMID: 14722102 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP.

    Krishnamurthy B, Dudek NL, McKenzie MD, Purcell AW, Brooks AG, Gellert S, Colman PG, Harrison LC, Lew AM, Thomas HE, Kay TW.

    J Clin Invest. 2006 Dec;116(12):3258-65.PMID: 17143333 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Identification of CD4+ T cell-specific epitopes of islet-specific glucose-6-phosphatase catalytic subunit-related protein: a novel beta cell autoantigen in type 1 diabetes.

    Mukherjee R, Wagar D, Stephens TA, Lee-Chan E, Singh B.

    J Immunol. 2005 May 1;174(9):5306-15.PMID: 15843527 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    A novel transgenic mouse model reveals humanlike regulation of an 8-kbp human TERT gene promoter fragment in normal and tumor tissues.

    Ritz JM, Kühle O, Riethdorf S, Sipos B, Deppert W, Englert C, Günes C.

    Cancer Res. 2005 Feb 15;65(4):1187-96.PMID: 15735002 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

    Lieberman SM, Evans AM, Han B, Takaki T, Vinnitskaya Y, Caldwell JA, Serreze DV, Shabanowitz J, Hunt DF, Nathenson SG, Santamaria P, DiLorenzo TP.

    Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8384-8. Epub 2003 Jun 18.PMID: 12815107 [PubMed - indexed for MEDLINE]Related articlesFree article