PubMed

Advancing insulin therapy in type 2 diabetes previously treated with glargine plus oral agents: prandial premixed (insulin lispro protamine suspension/lispro) versus basal/bolus (glargine/lispro) therapy.

Rosenstock J, Ahmann AJ, Colon G, Scism-Bacon J, Jiang H, Martin S.

Diabetes Care. 2008 Jan;31(1):20-5. Epub 2007 Oct 12.PMID: 17934150 [PubMed - indexed for MEDLINE]Related articlesFree article

Mealtime 50/50 basal + prandial insulin analogue mixture with a basal insulin analogue, both plus metformin, in the achievement of target HbA1c and pre- and postprandial blood glucose levels in patients with type 2 diabetes: a multinational, 24-week, randomized, open-label, parallel-group comparison.

Robbins DC, Beisswenger PJ, Ceriello A, Goldberg RB, Moses RG, Pagkalos EM, Milicevic Z, Jones CA, Sarwat S, Tan MH.

Clin Ther. 2007 Nov;29(11):2349-64.PMID: 18158076 [PubMed - indexed for MEDLINE]Related articles

Twice-daily pre-mixed insulin rather than basal insulin therapy alone results in better overall glycaemic control in patients with Type 2 diabetes.

Malone JK, Bai S, Campaigne BN, Reviriego J, Augendre-Ferrante B.

Diabet Med. 2005 Apr;22(4):374-81.PMID: 15787659 [PubMed - indexed for MEDLINE]Related articles

Combined therapy with insulin lispro Mix 75/25 plus metformin or insulin glargine plus metformin: a 16-week, randomized, open-label, crossover study in patients with type 2 diabetes beginning insulin therapy.

Malone JK, Kerr LF, Campaigne BN, Sachson RA, Holcombe JH; Lispro Mixture-Glargine Study Group.

Clin Ther. 2004 Dec;26(12):2034-44. Erratum in: Clin Ther. 2005 Jul;27(7):1112. PMID: 15823767 [PubMed - indexed for MEDLINE]Related articles

DURAbility of basal versus lispro mix 75/25 insulin efficacy (DURABLE) trial 24-week results: safety and efficacy of insulin lispro mix 75/25 versus insulin glargine added to oral antihyperglycemic drugs in patients with type 2 diabetes.

Buse JB, Wolffenbuttel BH, Herman WH, Shemonsky NK, Jiang HH, Fahrbach JL, Scism-Bacon JL, Martin SA.

Diabetes Care. 2009 Jun;32(6):1007-13. Epub 2009 Mar 31.PMID: 19336625 [PubMed - indexed for MEDLINE]Related articlesFree article

Addition of neutral protamine lispro insulin or insulin glargine to oral type 2 diabetes regimens for patients with suboptimal glycemic control: a randomized trial.

Esposito K, Ciotola M, Maiorino MI, Gualdiero R, Schisano B, Ceriello A, Beneduce F, Feola G, Giugliano D.

Ann Intern Med. 2008 Oct 21;149(8):531-9.PMID: 18936501 [PubMed - indexed for MEDLINE]Related articlesFree article

Prandial insulin substitution with insulin lispro or insulin lispro mid mixture vs. basal therapy with insulin glargine: a randomized controlled trial in patients with type 2 diabetes beginning insulin therapy.

Kazda C, Hülstrunk H, Helsberg K, Langer F, Forst T, Hanefeld M.

J Diabetes Complications. 2006 May-Jun;20(3):145-52.PMID: 16632233 [PubMed - indexed for MEDLINE]Related articles

A comparison of intensive mixture therapy with basal insulin therapy in insulin-naïve patients with type 2 diabetes receiving oral antidiabetes agents.

Jacober SJ, Scism-Bacon JL, Zagar AJ.

Diabetes Obes Metab. 2006 Jul;8(4):448-55.PMID: 16776752 [PubMed - indexed for MEDLINE]Related articles

Humalog Mix 25 in patients with type 2 diabetes which do not achieve acceptable glycemic control with oral agents: results from a phase III, randomized, parallel study.

Tîrgovişte CI, Străchinariu R, Farcaşiu E, Milicevic Z, Teodorescu G.

Rom J Intern Med. 2003;41(2):153-62.PMID: 15526500 [PubMed - indexed for MEDLINE]Related articles

Triple therapy in type 2 diabetes: insulin glargine or rosiglitazone added to combination therapy of sulfonylurea plus metformin in insulin-naive patients.

Rosenstock J, Sugimoto D, Strange P, Stewart JA, Soltes-Rak E, Dailey G.

Diabetes Care. 2006 Mar;29(3):554-9.PMID: 16505505 [PubMed - indexed for MEDLINE]Related articlesFree article

Tolerability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2 diabetes previously uncontrolled with metformin or a sulfonylurea: a multinational, randomized, open-label, two-period, crossover noninferiority trial.

Barnett AH, Burger J, Johns D, Brodows R, Kendall DM, Roberts A, Trautmann ME.

Clin Ther. 2007 Nov;29(11):2333-48.PMID: 18158075 [PubMed - indexed for MEDLINE]Related articles

Once-daily basal insulin glargine versus thrice-daily prandial insulin lispro in people with type 2 diabetes on oral hypoglycaemic agents (APOLLO): an open randomised controlled trial.

Bretzel RG, Nuber U, Landgraf W, Owens DR, Bradley C, Linn T.

Lancet. 2008 Mar 29;371(9618):1073-84. Erratum in: Lancet. 2008 Aug 30;372(9640):718. PMID: 18374840 [PubMed - indexed for MEDLINE]Related articles

Intensive replacement of basal insulin in patients with type 1 diabetes given rapid-acting insulin analog at mealtime: a 3-month comparison between administration of NPH insulin four times daily and glargine insulin at dinner or bedtime.

Rossetti P, Pampanelli S, Fanelli C, Porcellati F, Costa E, Torlone E, Scionti L, Bolli GB.

Diabetes Care. 2003 May;26(5):1490-6.PMID: 12716810 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of insulin lispro mixture 25/75 with insulin glargine during a 24-h standardized test-meal period in patients with Type 2 diabetes.

Roach P, Malone JK.

Diabet Med. 2006 Jul;23(7):743-9.PMID: 16842478 [PubMed - indexed for MEDLINE]Related articles

A randomized clinical trial comparing breakfast, dinner, or bedtime administration of insulin glargine in patients with type 1 diabetes.

Hamann A, Matthaei S, Rosak C, Silvestre L; HOE901/4007 Study Group.

Diabetes Care. 2003 Jun;26(6):1738-44.PMID: 12766103 [PubMed - indexed for MEDLINE]Related articlesFree article

Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trial.

Heine RJ, Van Gaal LF, Johns D, Mihm MJ, Widel MH, Brodows RG; GWAA Study Group.

Ann Intern Med. 2005 Oct 18;143(8):559-69.PMID: 16230722 [PubMed - indexed for MEDLINE]Related articlesFree article

[Post-hoc analyses of type 2 diabetes patients switch from premixed insulin regimen to basal insulin plus oral hypoglycemic agents regimen]

Bu S, Guo XH, Yang WY, Lu GZ, Yang ZJ, Ren TT, Gao Y.

Zhonghua Yi Xue Za Zhi. 2007 Nov 27;87(44):3115-8. Chinese. PMID: 18269868 [PubMed - indexed for MEDLINE]Related articles

Comparison of a multiple daily insulin injection regimen (basal once-daily glargine plus mealtime lispro) and continuous subcutaneous insulin infusion (lispro) in type 1 diabetes: a randomized open parallel multicenter study.

Bolli GB, Kerr D, Thomas R, Torlone E, Sola-Gazagnes A, Vitacolonna E, Selam JL, Home PD.

Diabetes Care. 2009 Jul;32(7):1170-6. Epub 2009 Apr 23. Erratum in: Diabetes Care. 2009 Oct;32(10):1944. PMID: 19389820 [PubMed - indexed for MEDLINE]Related articlesFree article

Treatment satisfaction and quality of life with insulin glargine plus insulin lispro compared with NPH insulin plus unmodified human insulin in individuals with type 1 diabetes.

Ashwell SG, Bradley C, Stephens JW, Witthaus E, Home PD.

Diabetes Care. 2008 Jun;31(6):1112-7. Epub 2008 Mar 13.PMID: 18339977 [PubMed - indexed for MEDLINE]Related articlesFree article

Prandial premixed insulin analogue regimens versus basal insulin analogue regimens in the management of type 2 diabetes: an evidence-based comparison.

Ilag LL, Kerr L, Malone JK, Tan MH.

Clin Ther. 2007 Jun;29(6 Pt 1):1254-70. Review.PMID: 18036388 [PubMed - indexed for MEDLINE]Related articles