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    Results: 1 to 20 of 315

    1.

    Inactivation of glyceraldehyde-3-phosphate dehydrogenase by fumarate in diabetes: formation of S-(2-succinyl)cysteine, a novel chemical modification of protein and possible biomarker of mitochondrial stress.

    Blatnik M, Frizzell N, Thorpe SR, Baynes JW.

    Diabetes. 2008 Jan;57(1):41-9. Epub 2007 Oct 12.PMID: 17934141 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Succination of proteins by fumarate: mechanism of inactivation of glyceraldehyde-3-phosphate dehydrogenase in diabetes.

    Blatnik M, Thorpe SR, Baynes JW.

    Ann N Y Acad Sci. 2008 Apr;1126:272-5.PMID: 18448829 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate.

    Alderson NL, Wang Y, Blatnik M, Frizzell N, Walla MD, Lyons TJ, Alt N, Carson JA, Nagai R, Thorpe SR, Baynes JW.

    Arch Biochem Biophys. 2006 Jun 1;450(1):1-8. Epub 2006 Mar 22.PMID: 16624247 [PubMed - indexed for MEDLINE]Related articles

    4.

    Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress.

    Nagai R, Brock JW, Blatnik M, Baatz JE, Bethard J, Walla MD, Thorpe SR, Baynes JW, Frizzell N.

    J Biol Chem. 2007 Nov 23;282(47):34219-28. Epub 2007 Aug 28.PMID: 17726021 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Molecular basis of enzyme inactivation by an endogenous electrophile 4-hydroxy-2-nonenal: identification of modification sites in glyceraldehyde-3-phosphate dehydrogenase.

    Ishii T, Tatsuda E, Kumazawa S, Nakayama T, Uchida K.

    Biochemistry. 2003 Apr 1;42(12):3474-80.PMID: 12653551 [PubMed - indexed for MEDLINE]Related articles

    6.

    Glyceraldehyde phosphate dehydrogenase oxidation during cardiac ischemia and reperfusion.

    Eaton P, Wright N, Hearse DJ, Shattock MJ.

    J Mol Cell Cardiol. 2002 Nov;34(11):1549-60.PMID: 12431453 [PubMed - indexed for MEDLINE]Related articles

    7.

    Role of glyceraldehyde 3-phosphate dehydrogenase in the development and progression of diabetic retinopathy.

    Kanwar M, Kowluru RA.

    Diabetes. 2009 Jan;58(1):227-34. Epub 2008 Oct 13.PMID: 18852331 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Reversible post-translational modification of proteins by nitrated fatty acids in vivo.

    Batthyany C, Schopfer FJ, Baker PR, Durán R, Baker LM, Huang Y, Cerveñansky C, Branchaud BP, Freeman BA.

    J Biol Chem. 2006 Jul 21;281(29):20450-63. Epub 2006 May 8.PMID: 16682416 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Succination of thiol groups in adipose tissue proteins in diabetes: succination inhibits polymerization and secretion of adiponectin.

    Frizzell N, Rajesh M, Jepson MJ, Nagai R, Carson JA, Thorpe SR, Baynes JW.

    J Biol Chem. 2009 Sep 18;284(38):25772-81. Epub 2009 Jul 10.PMID: 19592500 [PubMed - indexed for MEDLINE]Related articles

    10.

    Glyceraldehyde-3-phosphate dehydrogenase inactivation by peroxynitrite.

    Souza JM, Radi R.

    Arch Biochem Biophys. 1998 Dec 15;360(2):187-94.PMID: 9851830 [PubMed - indexed for MEDLINE]Related articles

    11.

    The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell death.

    Nakajima H, Amano W, Fujita A, Fukuhara A, Azuma YT, Hata F, Inui T, Takeuchi T.

    J Biol Chem. 2007 Sep 7;282(36):26562-74. Epub 2007 Jul 5.PMID: 17613523 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Maternal diabetes in vivo and high glucose in vitro diminish GAPDH activity in rat embryos.

    Wentzel P, Ejdesjö A, Eriksson UJ.

    Diabetes. 2003 May;52(5):1222-8.PMID: 12716756 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): evaluation of the importance of S-nitrosothiols as inhibitors of DDAH activity in vitro and in vivo in humans.

    Chobanyan K, Thum T, Suchy MT, Zhu B, Mitschke A, Gutzki FM, Beckmann B, Stichtenoth DO, Tsikas D.

    J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Oct 15;858(1-2):32-41. Epub 2007 Aug 7.PMID: 17825631 [PubMed - indexed for MEDLINE]Related articles

    14.

    Coenzyme site-directed mutants of photosynthetic A4-GAPDH show selectively reduced NADPH-dependent catalysis, similar to regulatory AB-GAPDH inhibited by oxidized thioredoxin.

    Sparla F, Fermani S, Falini G, Zaffagnini M, Ripamonti A, Sabatino P, Pupillo P, Trost P.

    J Mol Biol. 2004 Jul 23;340(5):1025-37.PMID: 15236965 [PubMed - indexed for MEDLINE]Related articles

    15.

    Acrylonitrile irreversibly inactivates glyceraldehyde-3-phosphate dehydrogenase by alkylating the catalytically active cysteine 149.

    Campian EC, Cai J, Benz FW.

    Chem Biol Interact. 2002 Aug 15;140(3):279-91.PMID: 12204582 [PubMed - indexed for MEDLINE]Related articles

    16.

    Submicromolar concentrations of palmitoyl-CoA specifically thioesterify cysteine 244 in glyceraldehyde-3-phosphate dehydrogenase inhibiting enzyme activity: a novel mechanism potentially underlying fatty acid induced insulin resistance.

    Yang J, Gibson B, Snider J, Jenkins CM, Han X, Gross RW.

    Biochemistry. 2005 Sep 6;44(35):11903-12.PMID: 16128592 [PubMed - indexed for MEDLINE]Related articles

    17.

    GAPDH is conformationally and functionally altered in association with oxidative stress in mouse models of amyotrophic lateral sclerosis.

    Pierce A, Mirzaei H, Muller F, De Waal E, Taylor AB, Leonard S, Van Remmen H, Regnier F, Richardson A, Chaudhuri A.

    J Mol Biol. 2008 Oct 24;382(5):1195-210. Epub 2008 Aug 6.PMID: 18706911 [PubMed - indexed for MEDLINE]Related articles

    18.

    Regulation of plant cytosolic glyceraldehyde 3-phosphate dehydrogenase isoforms by thiol modifications.

    Holtgrefe S, Gohlke J, Starmann J, Druce S, Klocke S, Altmann B, Wojtera J, Lindermayr C, Scheibe R.

    Physiol Plant. 2008 Jun;133(2):211-28. Epub 2008 Feb 21.PMID: 18298409 [PubMed - indexed for MEDLINE]Related articles

    19.

    Different thermostability of skeletal muscle glyceraldehyde-3-phosphate dehydrogenase from hibernating and euthermic jerboa (Jaculus orientalis).

    Iddar A, Campos LA, Sancho J, Serrano A, Soukri A.

    Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003 Oct;35(10):891-6.PMID: 14515205 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Inhibition of glyceraldehyde-3-phosphate dehydrogenase by pentalenolactone. 2. Identification of the site of alkylation by tetrahydropentalenolactone.

    Cane DE, Sohng JK.

    Biochemistry. 1994 May 31;33(21):6524-30.PMID: 8204587 [PubMed - indexed for MEDLINE]Related articles

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