PubMed

CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo.

Knuefermann P, Baumgarten G, Koch A, Schwederski M, Velten M, Ehrentraut H, Mersmann J, Meyer R, Hoeft A, Zacharowski K, Grohé C.

Respir Res. 2007 Oct 9;8:72.PMID: 17925007 [PubMed - indexed for MEDLINE]Related articlesFree article

Bacterial DNA induces myocardial inflammation and reduces cardiomyocyte contractility: role of toll-like receptor 9.

Knuefermann P, Schwederski M, Velten M, Krings P, Ehrentraut H, Rüdiger M, Boehm O, Fink K, Dreiner U, Grohé C, Hoeft A, Baumgarten G, Koch A, Zacharowski K, Meyer R.

Cardiovasc Res. 2008 Apr 1;78(1):26-35. Epub 2008 Jan 14.PMID: 18194990 [PubMed - indexed for MEDLINE]Related articlesFree article

CpG DNA modulates interleukin 1beta-induced interleukin-8 expression in human bronchial epithelial (16HBE14o-) cells.

Parilla NW, Hughes VS, Lierl KM, Wong HR, Page K.

Respir Res. 2006 Jun 1;7:84.PMID: 16740161 [PubMed - indexed for MEDLINE]Related articlesFree article

A threshold level of TLR9 mRNA predicts cellular responsiveness to CpG-ODN in haematological and non-haematological tumour cell lines.

Assaf A, Esteves H, Curnow SJ, Browning MJ.

Cell Immunol. 2009;259(1):90-9. Epub 2009 Jun 6.PMID: 19573862 [PubMed - indexed for MEDLINE]Related articles

Suppressive oligodeoxynucleotides inhibit CpG-induced inflammation of the mouse lung.

Yamada H, Ishii KJ, Klinman DM.

Crit Care Med. 2004 Oct;32(10):2045-9.PMID: 15483413 [PubMed - indexed for MEDLINE]Related articles

Antimalarial artesunate protects sepsis model mice against heat-killed Escherichia coli challenge by decreasing TLR4, TLR9 mRNA expressions and transcription factor NF-kappa B activation.

Li B, Zhang R, Li J, Zhang L, Ding G, Luo P, He S, Dong Y, Jiang W, Lu Y, Cao H, Zheng J, Zhou H.

Int Immunopharmacol. 2008 Mar;8(3):379-89. Epub 2007 Dec 7.PMID: 18279792 [PubMed - indexed for MEDLINE]Related articles

Toll-like receptor 9 regulates tumor necrosis factor-alpha expression by different mechanisms. Implications for osteoclastogenesis.

Amcheslavsky A, Zou W, Bar-Shavit Z.

J Biol Chem. 2004 Dec 24;279(52):54039-45. Epub 2004 Oct 14.PMID: 15485822 [PubMed - indexed for MEDLINE]Related articlesFree article

Chloroquine protects mice from challenge with CpG ODN and LPS by decreasing proinflammatory cytokine release.

Hong Z, Jiang Z, Liangxi W, Guofu D, Ping L, Yongling L, Wendong P, Minghai W.

Int Immunopharmacol. 2004 Feb;4(2):223-34.PMID: 14996414 [PubMed - indexed for MEDLINE]Related articles

Low-tidal-volume mechanical ventilation induces a toll-like receptor 4-dependent inflammatory response in healthy mice.

Vaneker M, Joosten LA, Heunks LM, Snijdelaar DG, Halbertsma FJ, van Egmond J, Netea MG, van der Hoeven JG, Scheffer GJ.

Anesthesiology. 2008 Sep;109(3):465-72.PMID: 18719444 [PubMed - indexed for MEDLINE]Related articlesFree article

Silencing Toll-like receptor-9 in Pseudomonas aeruginosa keratitis.

Huang X, Barrett RP, McClellan SA, Hazlett LD.

Invest Ophthalmol Vis Sci. 2005 Nov;46(11):4209-16.PMID: 16249500 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired toll-like receptor 9 expression in alveolar macrophages with no sensitivity to CpG DNA.

Suzuki K, Suda T, Naito T, Ide K, Chida K, Nakamura H.

Am J Respir Crit Care Med. 2005 Apr 1;171(7):707-13. Epub 2005 Jan 7.PMID: 15640365 [PubMed - indexed for MEDLINE]Related articlesFree article

Inductive and suppressive networks regulate TLR9-dependent gene expression in vivo.

Klaschik S, Tross D, Klinman DM.

J Leukoc Biol. 2009 May;85(5):788-95. Epub 2009 Jan 29.PMID: 19179452 [PubMed - indexed for MEDLINE]Related articles

Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation.

Vollmer J, Weeratna RD, Jurk M, Samulowitz U, McCluskie MJ, Payette P, Davis HL, Schetter C, Krieg AM.

Immunology. 2004 Oct;113(2):212-23.PMID: 15379982 [PubMed - indexed for MEDLINE]Related articlesFree article

CpG ODNs treatments of HIV-1 infected patients may cause the decline of transmission in high risk populations - a review, hypothesis and implications.

Becker Y.

Virus Genes. 2005 Mar;30(2):251-66. Review.PMID: 15744581 [PubMed - indexed for MEDLINE]Related articles

Intratracheal synthetic CpG oligodeoxynucleotide causes acute lung injury with systemic inflammatory response.

Tasaka S, Kamata H, Miyamoto K, Nakano Y, Shinoda H, Kimizuka Y, Fujiwara H, Hasegawa N, Fujishima S, Miyasho T, Ishizaka A.

Respir Res. 2009 Sep 23;10:84.PMID: 19772669 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased intracellular TLR9 confers hyporesponsiveness of RAW264.7 cells to subsequent CpG ODN challenge.

Wei L, Hong Z, Jiang Z, Guofu D, Hongwei C, Liangxi W, Yongling L, Bin L, Ping L.

Int Immunopharmacol. 2006 Jun;6(6):935-46. Epub 2006 Feb 3.PMID: 16644479 [PubMed - indexed for MEDLINE]Related articles

Expression of Toll-like receptor 9 and response to bacterial CpG oligodeoxynucleotides in human intestinal epithelium.

Pedersen G, Andresen L, Matthiessen MW, Rask-Madsen J, Brynskov J.

Clin Exp Immunol. 2005 Aug;141(2):298-306.PMID: 15996194 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of modifications of heterocyclic bases in CpG dinucleotides on their immune-modulatory activity.

Vollmer J, Weeratna RD, Jurk M, Davis HL, Schetter C, Wüllner M, Wader T, Liu M, Kritzler A, Krieg AM.

J Leukoc Biol. 2004 Sep;76(3):585-93. Epub 2004 Jun 24.PMID: 15218053 [PubMed - indexed for MEDLINE]Related articlesFree article

Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway.

Nakamura K, Miyazato A, Xiao G, Hatta M, Inden K, Aoyagi T, Shiratori K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Suzuki K, Fujita J, Kaku M, Kawakami K.

J Immunol. 2008 Mar 15;180(6):4067-74.PMID: 18322216 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of Toll-like receptor 4 for the pathogenesis of acute lung injury in Gram-negative sepsis.

Baumgarten G, Knuefermann P, Wrigge H, Putensen C, Stapel H, Fink K, Meyer R, Hoeft A, Grohé C.

Eur J Anaesthesiol. 2006 Dec;23(12):1041-8. Epub 2006 Jul 12.PMID: 16836770 [PubMed - indexed for MEDLINE]Related articles