PubMed

In vivo evidence for inverse agonism of Agouti-related peptide in the central nervous system of proopiomelanocortin-deficient mice.

Tolle V, Low MJ.

Diabetes. 2008 Jan;57(1):86-94. Epub 2007 Oct 1.PMID: 17909095 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of melanocortin receptor activation and blockade on ethanol intake: a possible role for the melanocortin-4 receptor.

Navarro M, Cubero I, Chen AS, Chen HY, Knapp DJ, Breese GR, Marsh DJ, Thiele TE.

Alcohol Clin Exp Res. 2005 Jun;29(6):949-57.PMID: 15976520 [PubMed - indexed for MEDLINE]Related articlesFree article

Agouti-related protein (83-132) is a competitive antagonist at the human melanocortin-4 receptor: no evidence for differential interactions with pro-opiomelanocortin-derived ligands.

Pritchard LE, Armstrong D, Davies N, Oliver RL, Schmitz CA, Brennand JC, Wilkinson GF, White A.

J Endocrinol. 2004 Jan;180(1):183-91.PMID: 14709157 [PubMed - indexed for MEDLINE]Related articlesFree article

Food deprivation decreases responsiveness of ventromedial hypothalamic neurons to melanocortins.

Li YZ, Davidowa H.

J Neurosci Res. 2004 Aug 15;77(4):596-602.PMID: 15264229 [PubMed - indexed for MEDLINE]Related articles

The role of the melanocortin system and the melanocortin-4 receptor in ring dove (Streptopelia risoria) feeding behavior.

Strader AD, Schiöth HB, Buntin JD.

Brain Res. 2003 Jan 17;960(1-2):112-21.PMID: 12505663 [PubMed - indexed for MEDLINE]Related articles

Effects of agouti-related protein on metabolism and hypothalamic neuropeptide gene expression.

Korner J, Wissig S, Kim A, Conwell IM, Wardlaw SL.

J Neuroendocrinol. 2003 Dec;15(12):1116-21.PMID: 14636173 [PubMed - indexed for MEDLINE]Related articles

MTII attenuates ghrelin- and food deprivation-induced increases in food hoarding and food intake.

Keen-Rhinehart E, Bartness TJ.

Horm Behav. 2007 Dec;52(5):612-20. Epub 2007 Aug 10.PMID: 17826779 [PubMed - indexed for MEDLINE]Related articlesFree article

Agouti-related peptide and MC3/4 receptor agonists both inhibit excitatory hypothalamic ventromedial nucleus neurons.

Fu LY, van den Pol AN.

J Neurosci. 2008 May 21;28(21):5433-49.PMID: 18495877 [PubMed - indexed for MEDLINE]Related articlesFree article

Peripherally administered [Nle4,D-Phe7]-alpha-melanocyte stimulating hormone increases resting metabolic rate, while peripheral agouti-related protein has no effect, in wild type C57BL/6 and ob/ob mice.

Hoggard N, Rayner DV, Johnston SL, Speakman JR.

J Mol Endocrinol. 2004 Dec;33(3):693-703.PMID: 15591028 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of melanocortin receptor ligands on thyrotropin-releasing hormone release: evidence for the differential roles of melanocortin 3 and 4 receptors.

Kim MS, Small CJ, Russell SH, Morgan DG, Abbott CR, alAhmed SH, Hay DL, Ghatei MA, Smith DM, Bloom SR.

J Neuroendocrinol. 2002 Apr;14(4):276-82.PMID: 11963824 [PubMed - indexed for MEDLINE]Related articles

The central melanocortin system and the integration of short- and long-term regulators of energy homeostasis.

Ellacott KL, Cone RD.

Recent Prog Horm Res. 2004;59:395-408. Review.PMID: 14749511 [PubMed - indexed for MEDLINE]Related articlesFree article

Pituitary adenylate cyclase-activating polypeptide inhibits food intake in mice through activation of the hypothalamic melanocortin system.

Mounien L, Do Rego JC, Bizet P, Boutelet I, Gourcerol G, Fournier A, Brabet P, Costentin J, Vaudry H, Jégou S.

Neuropsychopharmacology. 2009 Jan;34(2):424-35. Epub 2008 Jun 4.PMID: 18536705 [PubMed - indexed for MEDLINE]Related articles

Structure activity studies of the melanocortin-4 receptor by in vitro mutagenesis: identification of agouti-related protein (AGRP), melanocortin agonist and synthetic peptide antagonist interaction determinants.

Haskell-Luevano C, Cone RD, Monck EK, Wan YP.

Biochemistry. 2001 May 22;40(20):6164-79.PMID: 11352754 [PubMed - indexed for MEDLINE]Related articles

Long-term orexigenic effects of AgRP-(83---132) involve mechanisms other than melanocortin receptor blockade.

Hagan MM, Rushing PA, Pritchard LM, Schwartz MW, Strack AM, Van Der Ploeg LH, Woods SC, Seeley RJ.

Am J Physiol Regul Integr Comp Physiol. 2000 Jul;279(1):R47-52.PMID: 10896863 [PubMed - indexed for MEDLINE]Related articles

A C-terminal fragment of Agouti-related protein increases feeding and antagonizes the effect of alpha-melanocyte stimulating hormone in vivo.

Rossi M, Kim MS, Morgan DG, Small CJ, Edwards CM, Sunter D, Abusnana S, Goldstone AP, Russell SH, Stanley SA, Smith DM, Yagaloff K, Ghatei MA, Bloom SR.

Endocrinology. 1998 Oct;139(10):4428-31.PMID: 9751529 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin infusion and obesity in mouse cause alterations in the hypothalamic melanocortin system.

Gout J, Sarafian D, Tirard J, Blondet A, Vigier M, Rajas F, Mithieux G, Begeot M, Naville D.

Obesity (Silver Spring). 2008 Aug;16(8):1763-9. Epub 2008 Jun 12.PMID: 18551122 [PubMed - indexed for MEDLINE]Related articles

Effect of the melanocortin receptor stimulation or inhibition on ethanol intake in alcohol-preferring rats.

Polidori C, Geary N, Massi M.

Peptides. 2006 Jan;27(1):144-9. Epub 2005 Sep 28.PMID: 16198024 [PubMed - indexed for MEDLINE]Related articles

Phosphodiesterase inhibitor-dependent inverse agonism of agouti-related protein on melanocortin 4 receptor in sea bass (Dicentrarchus labrax).

Sánchez E, Rubio VC, Thompson D, Metz J, Flik G, Millhauser GL, Cerdá-Reverter JM.

Am J Physiol Regul Integr Comp Physiol. 2009 May;296(5):R1293-306. Epub 2009 Feb 18.PMID: 19225141 [PubMed - indexed for MEDLINE]Related articles

Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice.

Qian S, Chen H, Weingarth D, Trumbauer ME, Novi DE, Guan X, Yu H, Shen Z, Feng Y, Frazier E, Chen A, Camacho RE, Shearman LP, Gopal-Truter S, MacNeil DJ, Van der Ploeg LH, Marsh DJ.

Mol Cell Biol. 2002 Jul;22(14):5027-35.PMID: 12077332 [PubMed - indexed for MEDLINE]Related articlesFree article

Agouti-related protein functions as an inverse agonist at a constitutively active brain melanocortin-4 receptor.

Haskell-Luevano C, Monck EK.

Regul Pept. 2001 May 5;99(1):1-7.PMID: 11257308 [PubMed - indexed for MEDLINE]Related articles