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Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-beta/bone morphogenic protein signalling.
Hopwood B, Tsykin A, Findlay DM, Fazzalari NL.
Arthritis Res Ther. 2007;9(5):R100.PMID: 17900349 [PubMed - indexed for MEDLINE]Related articlesFree article
Gene expression profile of the bone microenvironment in human fragility fracture bone.
Bone. 2009 Jan;44(1):87-101. Epub 2008 Sep 10.PMID: 18840552 [PubMed - indexed for MEDLINE]Related articles
Identification of differentially expressed genes between osteoarthritic and normal trabecular bone from the intertrochanteric region of the proximal femur using cDNA microarray analysis.
Hopwood B, Gronthos S, Kuliwaba JS, Robey PG, Findlay DM, Fazzalari NL.
Bone. 2005 Apr;36(4):635-44.PMID: 15781004 [PubMed - indexed for MEDLINE]Related articles
Identification of differentially expressed genes in trabecular bone from the iliac crest of osteoarthritic patients.
Sánchez-Sabaté E, Alvarez L, Gil-Garay E, Munuera L, Vilaboa N.
Osteoarthritis Cartilage. 2009 Aug;17(8):1106-14. Epub 2009 Mar 12.PMID: 19303468 [PubMed - indexed for MEDLINE]Related articles
Identification of the molecular response of articular cartilage to injury, by microarray screening: Wnt-16 expression and signaling after injury and in osteoarthritis.
Dell'accio F, De Bari C, Eltawil NM, Vanhummelen P, Pitzalis C.
Arthritis Rheum. 2008 May;58(5):1410-21.PMID: 18438861 [PubMed - indexed for MEDLINE]Related articlesFree article
Differential gene expression of bone anabolic factors and trabecular bone architectural changes in the proximal femoral shaft of primary hip osteoarthritis patients.
Truong LH, Kuliwaba JS, Tsangari H, Fazzalari NL.
Arthritis Res Ther. 2006;8(6):R188.PMID: 17187661 [PubMed - indexed for MEDLINE]Related articlesFree article
Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts.
Tardif G, Hum D, Pelletier JP, Boileau C, Ranger P, Martel-Pelletier J.
Arthritis Rheum. 2004 Aug;50(8):2521-30.PMID: 15334466 [PubMed - indexed for MEDLINE]Related articlesFree article
Repression of anti-proliferative factor Tob1 in osteoarthritic cartilage.
Gebauer M, Saas J, Haag J, Dietz U, Takigawa M, Bartnik E, Aigner T.
Arthritis Res Ther. 2005;7(2):R274-84. Epub 2005 Jan 11.PMID: 15743474 [PubMed - indexed for MEDLINE]Related articlesFree article
Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury.
Dell'Accio F, De Bari C, El Tawil NM, Barone F, Mitsiadis TA, O'Dowd J, Pitzalis C.
Arthritis Res Ther. 2006;8(5):R139.PMID: 16893455 [PubMed - indexed for MEDLINE]Related articlesFree article
Alterations in endogenous osteogenic protein-1 with degeneration of human articular cartilage.
Merrihew C, Kumar B, Heretis K, Rueger DC, Kuettner KE, Chubinskaya S.
J Orthop Res. 2003 Sep;21(5):899-907.PMID: 12919879 [PubMed - indexed for MEDLINE]Related articles
Microarray analysis of differential gene expression in temporomandibular joint condylar cartilage after experimentally induced osteoarthritis.
Meng J, Ma X, Ma D, Xu C.
Osteoarthritis Cartilage. 2005 Dec;13(12):1115-25.PMID: 15905105 [PubMed - indexed for MEDLINE]Related articles
Differential transcriptome analysis of intraarticular lesional vs intact cartilage reveals new candidate genes in osteoarthritis pathophysiology.
Geyer M, Grässel S, Straub RH, Schett G, Dinser R, Grifka J, Gay S, Neumann E, Müller-Ladner U.
Osteoarthritis Cartilage. 2009 Mar;17(3):328-35. Epub 2008 Sep 4.PMID: 18775662 [PubMed - indexed for MEDLINE]Related articles
Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane.
Huber R, Hummert C, Gausmann U, Pohlers D, Koczan D, Guthke R, Kinne RW.
Arthritis Res Ther. 2008;10(4):R98. Epub 2008 Aug 22.PMID: 18721452 [PubMed - indexed for MEDLINE]Related articlesFree article
Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from the PI3K-AKT, WNT and TGFbeta signalling pathways.
Rizzatti EG, Falcão RP, Panepucci RA, Proto-Siqueira R, Anselmo-Lima WT, Okamoto OK, Zago MA.
Br J Haematol. 2005 Aug;130(4):516-26.PMID: 16098065 [PubMed - indexed for MEDLINE]Related articles
Expression profiles and functional analyses of Wnt-related genes in human joint disorders.
Nakamura Y, Nawata M, Wakitani S.
Am J Pathol. 2005 Jul;167(1):97-105.PMID: 15972956 [PubMed - indexed for MEDLINE]Related articlesFree article
The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kappaB ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an indicator of the metabolic state of these disease cells.
Kwan Tat S, Pelletier JP, Lajeunesse D, Fahmi H, Lavigne M, Martel-Pelletier J.
Clin Exp Rheumatol. 2008 Mar-Apr;26(2):295-304.PMID: 18565252 [PubMed - indexed for MEDLINE]Related articles
Wnt-beta-catenin signaling in the pathogenesis of osteoarthritis.
Corr M.
Nat Clin Pract Rheumatol. 2008 Oct;4(10):550-6. Review.PMID: 18820702 [PubMed - indexed for MEDLINE]Related articles
Expression of bone morphogenetic proteins and cartilage-derived morphogenetic proteins during osteophyte formation in humans.
Zoricic S, Maric I, Bobinac D, Vukicevic S.
J Anat. 2003 Mar;202(Pt 3):269-77.PMID: 12713267 [PubMed - indexed for MEDLINE]Related articlesFree article
The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein.
Maxis K, Delalandre A, Martel-Pelletier J, Pelletier JP, Duval N, Lajeunesse D.
Arthritis Res Ther. 2006;8(6):R181.PMID: 17156456 [PubMed - indexed for MEDLINE]Related articlesFree article
Up-regulation of the Wnt, estrogen receptor, insulin-like growth factor-I, and bone morphogenetic protein pathways in C57BL/6J osteoblasts as opposed to C3H/HeJ osteoblasts in part contributes to the differential anabolic response to fluid shear.
Lau KH, Kapur S, Kesavan C, Baylink DJ.
J Biol Chem. 2006 Apr 7;281(14):9576-88. Epub 2006 Feb 3.PMID: 16461770 [PubMed - indexed for MEDLINE]Related articlesFree article
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