PubMed

Stromal cell derived factor-1 (SDF-1)/CXCL12 attenuates diabetes in mice and promotes pancreatic beta-cell survival by activation of the prosurvival kinase Akt.

Yano T, Liu Z, Donovan J, Thomas MK, Habener JF.

Diabetes. 2007 Dec;56(12):2946-57. Epub 2007 Sep 18.PMID: 17878289 [PubMed - indexed for MEDLINE]Related articlesFree article

Stromal cell-derived factor-1 promotes survival of pancreatic beta cells by the stabilisation of beta-catenin and activation of transcription factor 7-like 2 (TCF7L2).

Liu Z, Habener JF.

Diabetologia. 2009 Aug;52(8):1589-98. Epub 2009 May 26.PMID: 19468708 [PubMed - indexed for MEDLINE]Related articles

LRRC4 inhibits human glioblastoma cells proliferation, invasion, and proMMP-2 activation by reducing SDF-1 alpha/CXCR4-mediated ERK1/2 and Akt signaling pathways.

Wu M, Chen Q, Li D, Li X, Li X, Huang C, Tang Y, Zhou Y, Wang D, Tang K, Cao L, Shen S, Li G.

J Cell Biochem. 2008 Jan 1;103(1):245-55.PMID: 17549698 [PubMed - indexed for MEDLINE]Related articles

Curcumin modulates SDF-1alpha/CXCR4-induced migration of human retinal endothelial cells (HRECs).

Sameermahmood Z, Balasubramanyam M, Saravanan T, Rema M.

Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3305-11.PMID: 18660423 [PubMed - indexed for MEDLINE]Related articlesFree article

Glial cell line-derived neurotrophic factor increases beta-cell mass and improves glucose tolerance.

Mwangi S, Anitha M, Mallikarjun C, Ding X, Hara M, Parsadanian A, Larsen CP, Thule P, Sitaraman SV, Anania F, Srinivasan S.

Gastroenterology. 2008 Mar;134(3):727-37. Epub 2008 Feb 1.PMID: 18241861 [PubMed - indexed for MEDLINE]Related articles

Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells.

Bouzakri K, Ribaux P, Tomas A, Parnaud G, Rickenbach K, Halban PA.

Diabetes. 2008 May;57(5):1195-204. Epub 2008 Feb 14.PMID: 18276765 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of gluconeogenesis in primary hepatocytes by stromal cell-derived factor-1 (SDF-1) through a c-Src/Akt-dependent signaling pathway.

Liu HY, Wen GB, Han J, Hong T, Zhuo D, Liu Z, Cao W.

J Biol Chem. 2008 Nov 7;283(45):30642-9. Epub 2008 Sep 11.PMID: 18786922 [PubMed - indexed for MEDLINE]Related articlesFree article

Akt activation, but not extracellular signal-regulated kinase activation, is required for SDF-1alpha/CXCR4-mediated migration of epitheloid carcinoma cells.

Peng SB, Peek V, Zhai Y, Paul DC, Lou Q, Xia X, Eessalu T, Kohn W, Tang S.

Mol Cancer Res. 2005 Apr;3(4):227-36.PMID: 15831676 [PubMed - indexed for MEDLINE]Related articlesFree article

Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways.

Wente W, Efanov AM, Brenner M, Kharitonenkov A, Köster A, Sandusky GE, Sewing S, Treinies I, Zitzer H, Gromada J.

Diabetes. 2006 Sep;55(9):2470-8.PMID: 16936195 [PubMed - indexed for MEDLINE]Related articlesFree article

Possible role of stromal-cell-derived factor-1/CXCR4 signaling on lymph node metastasis of oral squamous cell carcinoma.

Uchida D, Begum NM, Almofti A, Nakashiro K, Kawamata H, Tateishi Y, Hamakawa H, Yoshida H, Sato M.

Exp Cell Res. 2003 Nov 1;290(2):289-302.PMID: 14567988 [PubMed - indexed for MEDLINE]Related articles

The CXCR4/CXCL12 (SDF-1) signalling pathway protects non-obese diabetic mouse from autoimmune diabetes.

Aboumrad E, Madec AM, Thivolet C.

Clin Exp Immunol. 2007 Jun;148(3):432-9. Epub 2007 Mar 21.PMID: 17374136 [PubMed - indexed for MEDLINE]Related articlesFree article

Stromal cell-derived factor-1 (SDF-1) signalling regulates human placental trophoblast cell survival.

Jaleel MA, Tsai AC, Sarkar S, Freedman PV, Rubin LP.

Mol Hum Reprod. 2004 Dec;10(12):901-9. Epub 2004 Oct 8.PMID: 15475370 [PubMed - indexed for MEDLINE]Related articlesFree article

The stromal cell-derived factor-1alpha/CXCR4 ligand-receptor axis is critical for progenitor survival and migration in the pancreas.

Kayali AG, Van Gunst K, Campbell IL, Stotland A, Kritzik M, Liu G, Flodström-Tullberg M, Zhang YQ, Sarvetnick N.

J Cell Biol. 2003 Nov 24;163(4):859-69.PMID: 14638861 [PubMed - indexed for MEDLINE]Related articlesFree article

[Effect of chemokine stromal cell derived factor-1 and its receptor CXCR4 on the peritoneal carcinometastasis of gastric cancer]

Ding YL, Zhang JL, Tang SF, Fu QY, Li ZT.

Zhonghua Yi Xue Za Zhi. 2008 Jan 15;88(3):202-5. Chinese. PMID: 18361822 [PubMed - indexed for MEDLINE]Related articles

Targeted deletion of PTEN in smooth muscle cells results in vascular remodeling and recruitment of progenitor cells through induction of stromal cell-derived factor-1alpha.

Nemenoff RA, Simpson PA, Furgeson SB, Kaplan-Albuquerque N, Crossno J, Garl PJ, Cooper J, Weiser-Evans MC.

Circ Res. 2008 May 9;102(9):1036-45. Epub 2008 Mar 13.PMID: 18340011 [PubMed - indexed for MEDLINE]Related articlesFree article

Migration of endothelial progenitor cells mediated by stromal cell-derived factor-1alpha/CXCR4 via PI3K/Akt/eNOS signal transduction pathway.

Zheng H, Fu G, Dai T, Huang H.

J Cardiovasc Pharmacol. 2007 Sep;50(3):274-80.PMID: 17878755 [PubMed - indexed for MEDLINE]Related articles

Lactogens promote beta cell survival through JAK2/STAT5 activation and Bcl-XL upregulation.

Fujinaka Y, Takane K, Yamashita H, Vasavada RC.

J Biol Chem. 2007 Oct 19;282(42):30707-17. Epub 2007 Aug 29.PMID: 17728251 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of SDF-1alpha/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma.

Kajiyama H, Shibata K, Terauchi M, Ino K, Nawa A, Kikkawa F.

Int J Cancer. 2008 Jan 1;122(1):91-9.PMID: 17893878 [PubMed - indexed for MEDLINE]Related articles

Transgenic expression of stromal cell-derived factor-1/CXC chemokine ligand 12 enhances myeloid progenitor cell survival/antiapoptosis in vitro in response to growth factor withdrawal and enhances myelopoiesis in vivo.

Broxmeyer HE, Cooper S, Kohli L, Hangoc G, Lee Y, Mantel C, Clapp DW, Kim CH.

J Immunol. 2003 Jan 1;170(1):421-9.PMID: 12496427 [PubMed - indexed for MEDLINE]Related articlesFree article

Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis.

Hu X, Dai S, Wu WJ, Tan W, Zhu X, Mu J, Guo Y, Bolli R, Rokosh G.

Circulation. 2007 Aug 7;116(6):654-63. Epub 2007 Jul 23.PMID: 17646584 [PubMed - indexed for MEDLINE]Related articlesFree article