PubMed

Thrombospondin-1 is an endogenous activator of TGF-beta in experimental diabetic nephropathy in vivo.

Daniel C, Schaub K, Amann K, Lawler J, Hugo C.

Diabetes. 2007 Dec;56(12):2982-9. Epub 2007 Sep 18.PMID: 17878288 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasminogen activator inhibitor-1 deficiency retards diabetic nephropathy.

Nicholas SB, Aguiniga E, Ren Y, Kim J, Wong J, Govindarajan N, Noda M, Wang W, Kawano Y, Collins A, Hsueh WA.

Kidney Int. 2005 Apr;67(4):1297-307.PMID: 15780082 [PubMed - indexed for MEDLINE]Related articles

Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice.

Sharma K, Jin Y, Guo J, Ziyadeh FN.

Diabetes. 1996 Apr;45(4):522-30.PMID: 8603776 [PubMed - indexed for MEDLINE]Related articles

Correlation of enhanced thrombospondin-1 expression, TGF-beta signalling and proteinuria in human type-2 diabetic nephropathy.

Hohenstein B, Daniel C, Hausknecht B, Boehmer K, Riess R, Amann KU, Hugo CP.

Nephrol Dial Transplant. 2008 Dec;23(12):3880-7. Epub 2008 Jul 30.PMID: 18676351 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of upstream stimulatory factor 2 accelerates diabetic kidney injury.

Liu S, Shi L, Wang S.

Am J Physiol Renal Physiol. 2007 Nov;293(5):F1727-35. Epub 2007 Sep 19.PMID: 17881461 [PubMed - indexed for MEDLINE]Related articlesFree article

p27(Kip1) Knockout mice are protected from diabetic nephropathy: evidence for p27(Kip1) haplotype insufficiency.

Wolf G, Schanze A, Stahl RA, Shankland SJ, Amann K.

Kidney Int. 2005 Oct;68(4):1583-9.PMID: 16164635 [PubMed - indexed for MEDLINE]Related articles

Glomerular expression of thrombospondin-1, transforming growth factor beta and connective tissue growth factor at different stages of diabetic nephropathy and their interdependent roles in mesangial response to diabetic stimuli.

Wahab NA, Schaefer L, Weston BS, Yiannikouris O, Wright A, Babelova A, Schaefer R, Mason RM.

Diabetologia. 2005 Dec;48(12):2650-60. Epub 2005 Nov 4.PMID: 16270194 [PubMed - indexed for MEDLINE]Related articles

Suppressions of chronic glomerular injuries and TGF-beta 1 production by HGF in attenuation of murine diabetic nephropathy.

Mizuno S, Nakamura T.

Am J Physiol Renal Physiol. 2004 Jan;286(1):F134-43. Epub 2003 Sep 30.PMID: 14519594 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced TGF-beta/Smad signaling in the early stage of diabetic nephropathy is independent of the AT1a receptor.

Okazaki Y, Yamasaki Y, Uchida HA, Okamoto K, Satoh M, Maruyama K, Maeshima Y, Sugiyama H, Sugaya T, Kashihara N, Makino H.

Clin Exp Nephrol. 2007 Mar;11(1):77-87. Epub 2007 Mar 28.PMID: 17385003 [PubMed - indexed for MEDLINE]Related articles

Interference with TGF-beta signaling by Smad3-knockout in mice limits diabetic glomerulosclerosis without affecting albuminuria.

Wang A, Ziyadeh FN, Lee EY, Pyagay PE, Sung SH, Sheardown SA, Laping NJ, Chen S.

Am J Physiol Renal Physiol. 2007 Nov;293(5):F1657-65. Epub 2007 Sep 5.PMID: 17804483 [PubMed - indexed for MEDLINE]Related articlesFree article

Application of an adenoviral vector encoding soluble transforming growth factor-beta type II receptor to the treatment of diabetic nephropathy in mice.

Kondo T, Takemura G, Kosai K, Ohno T, Takahashi T, Esaki M, Goto K, Maruyama R, Murata I, Minatoguchi S, Fujiwara T, Fujiwara H.

Clin Exp Pharmacol Physiol. 2008 Nov;35(11):1288-93. Epub 2008 May 23.PMID: 18505441 [PubMed - indexed for MEDLINE]Related articles

Cellular basis of diabetic nephropathy: II. The transforming growth factor-beta system and diabetic nephropathy lesions in type 1 diabetes.

Huang C, Kim Y, Caramori ML, Fish AJ, Rich SS, Miller ME, Russell GB, Mauer M.

Diabetes. 2002 Dec;51(12):3577-81.PMID: 12453917 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective processing of the transforming growth factor-beta1 in azoxymethane-induced mouse colon tumors.

Guda K, Claffey KP, Dong M, Nambiar PR, Rosenberg DW.

Mol Carcinog. 2003 May;37(1):51-9.PMID: 12720300 [PubMed - indexed for MEDLINE]Related articles

High glucose induces macrophage inflammatory protein-3 alpha in renal proximal tubule cells via a transforming growth factor-beta 1 dependent mechanism.

Qi W, Chen X, Zhang Y, Holian J, Mreich E, Gilbert RE, Kelly DJ, Pollock CA.

Nephrol Dial Transplant. 2007 Nov;22(11):3147-53. Epub 2007 Jul 29.PMID: 17664181 [PubMed - indexed for MEDLINE]Related articlesFree article

Heterozygous mice for TGF-betaIIR gene are resistant to the progression of streptozotocin-induced diabetic nephropathy.

Kim HW, Kim BC, Song CY, Kim JH, Hong HK, Lee HS.

Kidney Int. 2004 Nov;66(5):1859-65.PMID: 15496156 [PubMed - indexed for MEDLINE]Related articles

The cyclin kinase inhibitor p21WAF1/CIP1 is required for glomerular hypertrophy in experimental diabetic nephropathy.

Al-Douahji M, Brugarolas J, Brown PA, Stehman-Breen CO, Alpers CE, Shankland SJ.

Kidney Int. 1999 Nov;56(5):1691-9.PMID: 10571777 [PubMed - indexed for MEDLINE]Related articlesFree article

[Mechanism of reversion of myocardial interstitial fibrosis in diabetic cardiomyopathy by valsartan]

Zhong M, Zhang Y, Miao Y, Li L, Gong HP, Ma X, Sun H, Zhang W.

Zhonghua Yi Xue Za Zhi. 2006 Jan 24;86(4):232-6. Chinese. PMID: 16677501 [PubMed - indexed for MEDLINE]Related articles

Thrombospondin-1 mediates distal tubule hypertrophy induced by glycated albumin.

Yang YL, Chuang LY, Guh JY, Liu SF, Hung MY, Liao TN, Huang YL.

Biochem J. 2004 Apr 1;379(Pt 1):89-97.PMID: 14683523 [PubMed - indexed for MEDLINE]Related articlesFree article

Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes.

Koya D, Haneda M, Nakagawa H, Isshiki K, Sato H, Maeda S, Sugimoto T, Yasuda H, Kashiwagi A, Ways DK, King GL, Kikkawa R.

FASEB J. 2000 Mar;14(3):439-47.PMID: 10698958 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose stimulation of transforming growth factor-beta bioactivity in mesangial cells is mediated by thrombospondin-1.

Poczatek MH, Hugo C, Darley-Usmar V, Murphy-Ullrich JE.

Am J Pathol. 2000 Oct;157(4):1353-63.PMID: 11021838 [PubMed - indexed for MEDLINE]Related articlesFree article