PubMed

Kaposi's sarcoma associated herpesvirus G-protein coupled receptor activation of cyclooxygenase-2 in vascular endothelial cells.

Shelby BD, LaMarca HL, McFerrin HE, Nelson AB, Lasky JA, Sun G, Myatt L, Offermann MK, Morris CA, Sullivan DE.

Virol J. 2007 Sep 14;4:87.PMID: 17868457 [PubMed - indexed for MEDLINE]Related articlesFree article

Cyclooxygenase 2 induced by Kaposi's sarcoma-associated herpesvirus early during in vitro infection of target cells plays a role in the maintenance of latent viral gene expression.

Sharma-Walia N, Raghu H, Sadagopan S, Sivakumar R, Veettil MV, Naranatt PP, Smith MM, Chandran B.

J Virol. 2006 Jul;80(13):6534-52.PMID: 16775340 [PubMed - indexed for MEDLINE]Related articlesFree article

The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor as a therapeutic target for the treatment of Kaposi's sarcoma.

Montaner S, Sodhi A, Ramsdell AK, Martin D, Hu J, Sawai ET, Gutkind JS.

Cancer Res. 2006 Jan 1;66(1):168-74.PMID: 16397229 [PubMed - indexed for MEDLINE]Related articlesFree article

The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor has broad signaling effects in primary effusion lymphoma cells.

Cannon M, Philpott NJ, Cesarman E.

J Virol. 2003 Jan;77(1):57-67.PMID: 12477810 [PubMed - indexed for MEDLINE]Related articlesFree article

Kaposi's sarcoma-associated herpesvirus upregulates angiogenin during infection of human dermal microvascular endothelial cells, which induces 45S rRNA synthesis, antiapoptosis, cell proliferation, migration, and angiogenesis.

Sadagopan S, Sharma-Walia N, Veettil MV, Bottero V, Levine R, Vart RJ, Chandran B.

J Virol. 2009 Apr;83(7):3342-64. Epub 2009 Jan 21.PMID: 19158252 [PubMed - indexed for MEDLINE]Related articlesFree article

Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6 and G-protein-coupled receptor regulate angiopoietin-2 expression in lymphatic endothelial cells.

Vart RJ, Nikitenko LL, Lagos D, Trotter MW, Cannon M, Bourboulia D, Gratrix F, Takeuchi Y, Boshoff C.

Cancer Res. 2007 May 1;67(9):4042-51.PMID: 17483315 [PubMed - indexed for MEDLINE]Related articlesFree article

An NF-kappaB gene expression signature contributes to Kaposi's sarcoma virus vGPCR-induced direct and paracrine neoplasia.

Martin D, Galisteo R, Ji Y, Montaner S, Gutkind JS.

Oncogene. 2008 Mar 20;27(13):1844-52. Epub 2007 Oct 15.PMID: 17934524 [PubMed - indexed for MEDLINE]Related articles

Kaposi's sarcoma-associated herpesvirus induces sustained levels of vascular endothelial growth factors A and C early during in vitro infection of human microvascular dermal endothelial cells: biological implications.

Sivakumar R, Sharma-Walia N, Raghu H, Veettil MV, Sadagopan S, Bottero V, Varga L, Levine R, Chandran B.

J Virol. 2008 Feb;82(4):1759-76. Epub 2007 Dec 5.PMID: 18057235 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of angiogenic chemokine CCL2 by human herpesvirus 8 chemokine receptor.

Choi YB, Nicholas J.

Virology. 2010 Feb 20;397(2):369-78. Epub 2009 Dec 9.PMID: 20004457 [PubMed - indexed for MEDLINE]Related articles

The phosphatase Shp2 is required for signaling by the Kaposi's sarcoma-associated herpesvirus viral GPCR in primary endothelial cells.

Bakken T, He M, Cannon ML.

Virology. 2010 Feb 20;397(2):379-88. Epub 2009 Dec 9.PMID: 20004456 [PubMed - indexed for MEDLINE]Related articles

Human herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus type 1 Tat.

Pati S, Foulke JS Jr, Barabitskaya O, Kim J, Nair BC, Hone D, Smart J, Feldman RA, Reitz M.

J Virol. 2003 May;77(10):5759-73.PMID: 12719569 [PubMed - indexed for MEDLINE]Related articlesFree article

Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasion.

Sharma-Walia N, Paul AG, Bottero V, Sadagopan S, Veettil MV, Kerur N, Chandran B.

PLoS Pathog. 2010 Feb 12;6(2):e1000777.PMID: 20169190 [PubMed - in process]Related articlesFree article

The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma.

Jensen KK, Manfra DJ, Grisotto MG, Martin AP, Vassileva G, Kelley K, Schwartz TW, Lira SA.

J Immunol. 2005 Mar 15;174(6):3686-94.PMID: 15749907 [PubMed - indexed for MEDLINE]Related articlesFree article

Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR.

Bais C, Van Geelen A, Eroles P, Mutlu A, Chiozzini C, Dias S, Silverstein RL, Rafii S, Mesri EA.

Cancer Cell. 2003 Feb;3(2):131-43.PMID: 12620408 [PubMed - indexed for MEDLINE]Related articles

The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor.

Sodhi A, Chaisuparat R, Hu J, Ramsdell AK, Manning BD, Sausville EA, Sawai ET, Molinolo A, Gutkind JS, Montaner S.

Cancer Cell. 2006 Aug;10(2):133-43.PMID: 16904612 [PubMed - indexed for MEDLINE]Related articles

Does dysregulated expression of a deregulated viral GPCR trigger Kaposi's sarcomagenesis?

Sodhi A, Montaner S, Gutkind JS.

FASEB J. 2004 Mar;18(3):422-7.PMID: 15003988 [PubMed - indexed for MEDLINE]Related articlesFree article

The KSHV G protein-coupled receptor signals via multiple pathways to induce transcription factor activation in primary effusion lymphoma cells.

Cannon ML, Cesarman E.

Oncogene. 2004 Jan 15;23(2):514-23.PMID: 14724579 [PubMed - indexed for MEDLINE]Related articles

Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma.

Yang TY, Chen SC, Leach MW, Manfra D, Homey B, Wiekowski M, Sullivan L, Jenh CH, Narula SK, Chensue SW, Lira SA.

J Exp Med. 2000 Feb 7;191(3):445-54.PMID: 10662790 [PubMed - indexed for MEDLINE]Related articlesFree article

Kaposi's sarcoma-associated herpesvirus utilizes an actin polymerization-dependent macropinocytic pathway to enter human dermal microvascular endothelial and human umbilical vein endothelial cells.

Raghu H, Sharma-Walia N, Veettil MV, Sadagopan S, Chandran B.

J Virol. 2009 May;83(10):4895-911. Epub 2009 Mar 11.PMID: 19279100 [PubMed - indexed for MEDLINE]Related articlesFree article

Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinases.

Qian LW, Xie J, Ye F, Gao SJ.

J Virol. 2007 Jul;81(13):7001-10. Epub 2007 Apr 18.PMID: 17442715 [PubMed - indexed for MEDLINE]Related articlesFree article