PubMed

Identification of novel candidate genes for type 2 diabetes from a genome-wide association scan in the Old Order Amish: evidence for replication from diabetes-related quantitative traits and from independent populations.

Rampersaud E, Damcott CM, Fu M, Shen H, McArdle P, Shi X, Shelton J, Yin J, Chang YP, Ott SH, Zhang L, Zhao Y, Mitchell BD, O'Connell J, Shuldiner AR.

Diabetes. 2007 Dec;56(12):3053-62. Epub 2007 Sep 10.PMID: 17846126 [PubMed - indexed for MEDLINE]Related articlesFree article

A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study: replication and integration with other genome-wide datasets.

Florez JC, Manning AK, Dupuis J, McAteer J, Irenze K, Gianniny L, Mirel DB, Fox CS, Cupples LA, Meigs JB.

Diabetes. 2007 Dec;56(12):3063-74. Epub 2007 Sep 11.PMID: 17848626 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide association with diabetes-related traits in the Framingham Heart Study.

Meigs JB, Manning AK, Fox CS, Florez JC, Liu C, Cupples LA, Dupuis J.

BMC Med Genet. 2007 Sep 19;8 Suppl 1:S16.PMID: 17903298 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies.

Hayes MG, Pluzhnikov A, Miyake K, Sun Y, Ng MC, Roe CA, Below JE, Nicolae RI, Konkashbaev A, Bell GI, Cox NJ, Hanis CL.

Diabetes. 2007 Dec;56(12):3033-44. Epub 2007 Sep 10.PMID: 17846124 [PubMed - indexed for MEDLINE]Related articlesFree article

A search for variants associated with young-onset type 2 diabetes in American Indians in a 100K genotyping array.

Hanson RL, Bogardus C, Duggan D, Kobes S, Knowlton M, Infante AM, Marovich L, Benitez D, Baier LJ, Knowler WC.

Diabetes. 2007 Dec;56(12):3045-52. Epub 2007 Sep 10.PMID: 17846125 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study.

Palmer ND, Goodarzi MO, Langefeld CD, Ziegler J, Norris JM, Haffner SM, Bryer-Ash M, Bergman RN, Wagenknecht LE, Taylor KD, Rotter JI, Bowden DW.

Diabetes. 2008 Apr;57(4):1093-100. Epub 2008 Feb 5.PMID: 18252897 [PubMed - indexed for MEDLINE]Related articlesFree article

Vesicle-associated membrane protein 4, a positional candidate gene on 1q24-q25, is not associated with type 2 diabetes in the Old Order Amish.

Sabra MM, Damcott C, Fu M, Ott S, O'Connell JR, Mitchell BD, Shuldiner AR.

Mol Genet Metab. 2005 Jun;85(2):133-9.PMID: 15896658 [PubMed - indexed for MEDLINE]Related articles

Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians.

Rong R, Hanson RL, Ortiz D, Wiedrich C, Kobes S, Knowler WC, Bogardus C, Baier LJ.

Diabetes. 2009 Feb;58(2):478-88. Epub 2008 Nov 13.PMID: 19008344 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence that Rho guanine nucleotide exchange factor 11 (ARHGEF11) on 1q21 is a type 2 diabetes susceptibility gene in the Old Order Amish.

Fu M, Sabra MM, Damcott C, Pollin TI, Ma L, Ott S, Shelton JC, Shi X, Reinhart L, O'Connell J, Mitchell BD, Baier LJ, Shuldiner AR.

Diabetes. 2007 May;56(5):1363-8. Epub 2007 Mar 16.PMID: 17369523 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance.

Damcott CM, Pollin TI, Reinhart LJ, Ott SH, Shen H, Silver KD, Mitchell BD, Shuldiner AR.

Diabetes. 2006 Sep;55(9):2654-9.PMID: 16936218 [PubMed - indexed for MEDLINE]Related articlesFree article

Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.

Takeuchi F, Serizawa M, Yamamoto K, Fujisawa T, Nakashima E, Ohnaka K, Ikegami H, Sugiyama T, Katsuya T, Miyagishi M, Nakashima N, Nawata H, Nakamura J, Kono S, Takayanagi R, Kato N.

Diabetes. 2009 Jul;58(7):1690-9. Epub 2009 Apr 28.PMID: 19401414 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study.

O'Donnell CJ, Cupples LA, D'Agostino RB, Fox CS, Hoffmann U, Hwang SJ, Ingellson E, Liu C, Murabito JM, Polak JF, Wolf PA, Demissie S.

BMC Med Genet. 2007 Sep 19;8 Suppl 1:S4.PMID: 17903303 [PubMed - indexed for MEDLINE]Related articlesFree article

A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study.

Kathiresan S, Manning AK, Demissie S, D'Agostino RB, Surti A, Guiducci C, Gianniny L, Burtt NP, Melander O, Orho-Melander M, Arnett DK, Peloso GM, Ordovas JM, Cupples LA.

BMC Med Genet. 2007 Sep 19;8 Suppl 1:S17.PMID: 17903299 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphism in the calsequestrin 1 (CASQ1) gene on chromosome 1q21 is associated with type 2 diabetes in the old order Amish.

Fu M, Damcott CM, Sabra M, Pollin TI, Ott SH, Wang J, Garant MJ, O'Connell JR, Mitchell BD, Shuldiner AR.

Diabetes. 2004 Dec;53(12):3292-9.PMID: 15561962 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes.

Staiger H, Machicao F, Kantartzis K, Schäfer SA, Kirchhoff K, Guthoff M, Silbernagel G, Stefan N, Fritsche A, Häring HU.

PLoS One. 2008 Aug 20;3(8):e3019.PMID: 18714373 [PubMed - indexed for MEDLINE]Related articlesFree article

Polymorphisms in both promoters of hepatocyte nuclear factor 4-alpha are associated with type 2 diabetes in the Amish.

Damcott CM, Hoppman N, Ott SH, Reinhart LJ, Wang J, Pollin TI, O'Connell JR, Mitchell BD, Shuldiner AR.

Diabetes. 2004 Dec;53(12):3337-41.PMID: 15561969 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluating the association of common PBX1 variants with type 2 diabetes.

Duesing K, Charpentier G, Marre M, Tichet J, Hercberg S, Balkau B, Froguel P, Gibson F.

BMC Med Genet. 2008 Feb 29;9:14.PMID: 18312624 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associated phenotypes in the French population.

Cheyssac C, Lecoeur C, Dechaume A, Bibi A, Charpentier G, Balkau B, Marre M, Froguel P, Gibson F, Vaxillaire M.

BMC Med Genet. 2006 May 5;7:44.PMID: 16677372 [PubMed - indexed for MEDLINE]Related articlesFree article

Genome-wide and fine-mapping linkage studies of type 2 diabetes and glucose traits in the Old Order Amish: evidence for a new diabetes locus on chromosome 14q11 and confirmation of a locus on chromosome 1q21-q24.

Hsueh WC, St Jean PL, Mitchell BD, Pollin TI, Knowler WC, Ehm MG, Bell CJ, Sakul H, Wagner MJ, Burns DK, Shuldiner AR.

Diabetes. 2003 Feb;52(2):550-7.PMID: 12540634 [PubMed - indexed for MEDLINE]Related articlesFree article

Calsquestrin 1 (CASQ1) gene polymorphisms under chromosome 1q21 linkage peak are associated with type 2 diabetes in Northern European Caucasians.

Das SK, Chu W, Zhang Z, Hasstedt SJ, Elbein SC.

Diabetes. 2004 Dec;53(12):3300-6.PMID: 15561963 [PubMed - indexed for MEDLINE]Related articlesFree article