PubMed

Microglial activation in the hippocampus of hypercholesterolemic rabbits occurs independent of increased amyloid production.

Xue QS, Sparks DL, Streit WJ.

J Neuroinflammation. 2007 Aug 24;4:20.PMID: 17718905 [PubMed - indexed for MEDLINE]Related articlesFree article

Water quality has a pronounced effect on cholesterol-induced accumulation of Alzheimer amyloid beta (Abeta) in rabbit brain.

Sparks DL, Lochhead J, Horstman D, Wagoner T, Martin T.

J Alzheimers Dis. 2002 Dec;4(6):523-9.PMID: 12515903 [PubMed - indexed for MEDLINE]Related articles

Cholesterol and cognition: rationale for the AD cholesterol-lowering treatment trial and sex-related Differences in beta-amyloid accumulation in the brains of spontaneously hypercholesterolemic Watanabe rabbits.

Sparks DL, Martins R, Martin T.

Ann N Y Acad Sci. 2002 Nov;977:356-66.PMID: 12480773 [PubMed - indexed for MEDLINE]Related articles

High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice.

Thirumangalakudi L, Prakasam A, Zhang R, Bimonte-Nelson H, Sambamurti K, Kindy MS, Bhat NR.

J Neurochem. 2008 Jul;106(1):475-85. Epub 2008 Jul 1.PMID: 18410513 [PubMed - indexed for MEDLINE]Related articles

Deposition of iron and beta-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets.

Ghribi O, Golovko MY, Larsen B, Schrag M, Murphy EJ.

J Neurochem. 2006 Oct;99(2):438-49. Erratum in: J Neurochem. 2007 Oct;103(1):423-4. PMID: 17029598 [PubMed - indexed for MEDLINE]Related articles

Cholesterol enhances classical conditioning of the rabbit heart rate response.

Schreurs BG, Smith-Bell CA, Darwish DS, Wang D, Burhans LB, Gonzales-Joekes J, Deci S, Stankovic G, Sparks DL.

Behav Brain Res. 2007 Jul 19;181(1):52-63. Epub 2007 Mar 30.PMID: 17466388 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol.

Sparks DL, Scheff SW, Hunsaker JC 3rd, Liu H, Landers T, Gross DR.

Exp Neurol. 1994 Mar;126(1):88-94.PMID: 8157129 [PubMed - indexed for MEDLINE]Related articles

Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease.

Streit WJ, Braak H, Xue QS, Bechmann I.

Acta Neuropathol. 2009 Oct;118(4):475-85. Epub 2009 Jun 10.PMID: 19513731 [PubMed - indexed for MEDLINE]Related articlesFree article

Glial beta-amyloid precursor protein: expression in the dentate gyrus after entorhinal cortex lesion.

Banati RB, Gehrmann J, Kreutzberg GW.

Neuroreport. 1994 Jun 27;5(11):1359-61.PMID: 7919199 [PubMed - indexed for MEDLINE]Related articles

Induction of complement proteins in a mouse model for cerebral microvascular A beta deposition.

Fan R, DeFilippis K, Van Nostrand WE.

J Neuroinflammation. 2007 Sep 18;4:22.PMID: 17877807 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of microglia in the brains of humans with heart disease and hypercholesterolemic rabbits.

Streit WJ, Sparks DL.

J Mol Med. 1997 Feb;75(2):130-8.PMID: 9083930 [PubMed - indexed for MEDLINE]Related articles

Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology.

Sparks DL, Friedland R, Petanceska S, Schreurs BG, Shi J, Perry G, Smith MA, Sharma A, Derosa S, Ziolkowski C, Stankovic G.

J Nutr Health Aging. 2006 Jul-Aug;10(4):247-54.PMID: 16886094 [PubMed - indexed for MEDLINE]Related articles

Apolipoprotein E expression in the cerebellum of normal and hypercholesterolemic rabbits.

Lafarga M, Crespo P, Berciano MT, Andres MA, Leon J.

Brain Res Mol Brain Res. 1994 Jan;21(1-2):115-23.PMID: 8164512 [PubMed - indexed for MEDLINE]Related articles

Proinflammatory stimuli are needed for induction of microglial cell-mediated AbetaPP_{244-C} and Abeta-neurotoxicity in hippocampal cultures.

Ramírez G, Rey S, von Bernhardi R.

J Alzheimers Dis. 2008 Sep;15(1):45-59.PMID: 18780966 [PubMed - indexed for MEDLINE]Related articles

Formation of multinucleated giant cells and microglial degeneration in rats expressing a mutant Cu/Zn superoxide dismutase gene.

Fendrick SE, Xue QS, Streit WJ.

J Neuroinflammation. 2007 Feb 28;4:9.PMID: 17328801 [PubMed - indexed for MEDLINE]Related articlesFree article

Microglial activation is required for Abeta clearance after intracranial injection of lipopolysaccharide in APP transgenic mice.

Herber DL, Mercer M, Roth LM, Symmonds K, Maloney J, Wilson N, Freeman MJ, Morgan D, Gordon MN.

J Neuroimmune Pharmacol. 2007 Jun;2(2):222-31. Epub 2007 Mar 27.PMID: 18040847 [PubMed - indexed for MEDLINE]Related articles

Clinical field-strength MRI of amyloid plaques induced by low-level cholesterol feeding in rabbits.

Ronald JA, Chen Y, Bernas L, Kitzler HH, Rogers KA, Hegele RA, Rutt BK.

Brain. 2009 May;132(Pt 5):1346-54. Epub 2009 Mar 17.PMID: 19293239 [PubMed - indexed for MEDLINE]Related articlesFree article

Up-regulation of PK11195 binding in areas of axonal degeneration coincides with early microglial activation in mouse brain.

Pedersen MD, Minuzzi L, Wirenfeldt M, Meldgaard M, Slidsborg C, Cumming P, Finsen B.

Eur J Neurosci. 2006 Aug;24(4):991-1000.PMID: 16930426 [PubMed - indexed for MEDLINE]Related articles

Stress-induced microglial activation may facilitate the progression of neurodegenerative disorders.

Sugama S.

Med Hypotheses. 2009 Dec;73(6):1031-4. Epub 2009 Jun 24.PMID: 19556067 [PubMed - indexed for MEDLINE]Related articles

Heat shock protein-90-induced microglial clearance of exogenous amyloid-beta1-42 in rat hippocampus in vivo.

Takata K, Kitamura Y, Tsuchiya D, Kawasaki T, Taniguchi T, Shimohama S.

Neurosci Lett. 2003 Jun 26;344(2):87-90.PMID: 12782334 [PubMed - indexed for MEDLINE]Related articles