PubMed

Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4', 5 tri-hydroxystilbene): molecular mechanisms and therapeutic potential.

Shankar S, Chen Q, Siddiqui I, Sarva K, Srivastava RK.

J Mol Signal. 2007 Aug 24;2:7.PMID: 17718901 [PubMed - in process]Related articlesFree article

Molecular mechanisms of resveratrol (3,4,5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells.

Shankar S, Siddiqui I, Srivastava RK.

Mol Cell Biochem. 2007 Oct;304(1-2):273-85. Epub 2007 Jul 17.PMID: 17636462 [PubMed - indexed for MEDLINE]Related articles

Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer.

Shankar S, Srivastava RK.

Int J Oncol. 2007 Apr;30(4):905-18.PMID: 17332930 [PubMed - indexed for MEDLINE]Related articles

Curcumin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells: molecular mechanisms of apoptosis, migration and angiogenesis.

Shankar S, Chen Q, Sarva K, Siddiqui I, Srivastava RK.

J Mol Signal. 2007 Oct 4;2:10.PMID: 17916240 [PubMed - in process]Related articlesFree article

Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway.

Hu H, Jiang C, Schuster T, Li GX, Daniel PT, Lü J.

Mol Cancer Ther. 2006 Jul;5(7):1873-82.PMID: 16891474 [PubMed - indexed for MEDLINE]Related articlesFree article

Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis.

Shankar S, Ganapathy S, Chen Q, Srivastava RK.

Mol Cancer. 2008 Jan 29;7:16.PMID: 18226269 [PubMed - indexed for MEDLINE]Related articlesFree article

Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis.

Shankar S, Ganapathy S, Srivastava RK.

Clin Cancer Res. 2008 Nov 1;14(21):6855-66.PMID: 18980980 [PubMed - indexed for MEDLINE]Related articlesFree article

Diallyl trisulfide increases the effectiveness of TRAIL and inhibits prostate cancer growth in an orthotopic model: molecular mechanisms.

Shankar S, Chen Q, Ganapathy S, Singh KP, Srivastava RK.

Mol Cancer Ther. 2008 Aug;7(8):2328-38.PMID: 18723480 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria.

Nagy K, Székely-Szüts K, Izeradjene K, Douglas L, Tillman M, Barti-Juhász H, Dominici M, Spano C, Luca Cervo G, Conte P, Houghton JA, Mihalik R, Kopper L, Peták I.

Pathol Oncol Res. 2006;12(3):133-42. Epub 2006 Sep 23.PMID: 16998592 [PubMed - indexed for MEDLINE]Related articlesFree article

Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells.

Fandy TE, Shankar S, Srivastava RK.

Mol Cancer. 2008 Jun 30;7:60.PMID: 18590557 [PubMed - indexed for MEDLINE]Related articlesFree article

Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression.

Ivanov VN, Partridge MA, Johnson GE, Huang SX, Zhou H, Hei TK.

Exp Cell Res. 2008 Mar 10;314(5):1163-76. Epub 2007 Dec 23.PMID: 18222423 [PubMed - indexed for MEDLINE]Related articles

Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling.

Fulda S, Debatin KM.

Eur J Cancer. 2005 Mar;41(5):786-98. Epub 2005 Jan 21.PMID: 15763656 [PubMed - indexed for MEDLINE]Related articles

Bax and Bak genes are essential for maximum apoptotic response by curcumin, a polyphenolic compound and cancer chemopreventive agent derived from turmeric, Curcuma longa.

Shankar S, Srivastava RK.

Carcinogenesis. 2007 Jun;28(6):1277-86. Epub 2007 Feb 2.PMID: 17277231 [PubMed - indexed for MEDLINE]Related articlesFree article

Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the downregulation of cell survival proteins and upregulation of death receptors.

Sung B, Park B, Yadav VR, Aggarwal BB.

J Biol Chem. 2010 Feb 12. [Epub ahead of print]PMID: 20154087 [PubMed - as supplied by publisher]Related articlesFree article

Mitochondrial transmembrane potential and reactive oxygen species generation regulate the enhanced effect of CCCP on TRAIL-induced SNU-638 cell apoptosis.

Chaudhari AA, Seol JW, Kang SJ, Park SY.

J Vet Med Sci. 2008 Jun;70(6):537-42.PMID: 18628592 [PubMed - indexed for MEDLINE]Related articlesFree article

The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation.

Rosato RR, Almenara JA, Coe S, Grant S.

Cancer Res. 2007 Oct 1;67(19):9490-500.PMID: 17909059 [PubMed - indexed for MEDLINE]Related articlesFree article

Resveratrol sensitizes androgen independent prostate cancer cells to death-receptor mediated apoptosis through multiple mechanisms.

Gill C, Walsh SE, Morrissey C, Fitzpatrick JM, Watson RW.

Prostate. 2007 Nov 1;67(15):1641-53.PMID: 17823925 [PubMed - indexed for MEDLINE]Related articles

BH3 mimetic obatoclax enhances TRAIL-mediated apoptosis in human pancreatic cancer cells.

Huang S, Okumura K, Sinicrope FA.

Clin Cancer Res. 2009 Jan 1;15(1):150-9.PMID: 19118042 [PubMed - indexed for MEDLINE]Related articlesFree article

Transfection of Smac/DIABLO sensitizes drug-resistant tumor cells to TRAIL or paclitaxel-induced apoptosis in vitro.

Mao HL, Liu PS, Zheng JF, Zhang PH, Zhou LG, Xin G, Liu C.

Pharmacol Res. 2007 Dec;56(6):483-92. Epub 2007 Sep 15.PMID: 18029193 [PubMed - indexed for MEDLINE]Related articles

Suberoylanilide hydroxamic acid (Zolinza/vorinostat) sensitizes TRAIL-resistant breast cancer cells orthotopically implanted in BALB/c nude mice.

Shankar S, Davis R, Singh KP, Kurzrock R, Ross DD, Srivastava RK.

Mol Cancer Ther. 2009 Jun;8(6):1596-605. Epub 2009 Jun 9.PMID: 19509267 [PubMed - indexed for MEDLINE]Related articles