PubMed

S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects.

Carmona MC, Louche K, Lefebvre B, Pilon A, Hennuyer N, Audinot-Bouchez V, Fievet C, Torpier G, Formstecher P, Renard P, Lefebvre P, Dacquet C, Staels B, Casteilla L, Pénicaud L; Consortium of the French Ministry of Research and Technology.

Diabetes. 2007 Nov;56(11):2797-808. Epub 2007 Aug 17.PMID: 17704298 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel selective peroxisome proliferator-activator receptor-gamma modulator-SPPARgammaM5 improves insulin sensitivity with diminished adverse cardiovascular effects.

Chang CH, McNamara LA, Wu MS, Muise ES, Tan Y, Wood HB, Meinke PT, Thompson JR, Doebber TW, Berger JP, McCann ME.

Eur J Pharmacol. 2008 Apr 14;584(1):192-201. Epub 2008 Feb 14.PMID: 18346728 [PubMed - indexed for MEDLINE]Related articles

T2384, a novel antidiabetic agent with unique peroxisome proliferator-activated receptor gamma binding properties.

Li Y, Wang Z, Furukawa N, Escaron P, Weiszmann J, Lee G, Lindstrom M, Liu J, Liu X, Xu H, Plotnikova O, Prasad V, Walker N, Learned RM, Chen JL.

J Biol Chem. 2008 Apr 4;283(14):9168-76. Epub 2008 Feb 7.PMID: 18263587 [PubMed - indexed for MEDLINE]Related articlesFree article

FK614, a novel peroxisome proliferator-activated receptor gamma modulator, induces differential transactivation through a unique ligand-specific interaction with transcriptional coactivators.

Fujimura T, Sakuma H, Konishi S, Oe T, Hosogai N, Kimura C, Aramori I, Mutoh S.

J Pharmacol Sci. 2005 Dec;99(4):342-52. Epub 2005 Nov 26.PMID: 16314690 [PubMed - indexed for MEDLINE]Related articlesFree article

A selective peroxisome proliferator-activated receptor gamma modulator with distinct fat cell regulation properties.

Fujimura T, Kimura C, Oe T, Takata Y, Sakuma H, Aramori I, Mutoh S.

J Pharmacol Exp Ther. 2006 Aug;318(2):863-71. Epub 2006 May 8.PMID: 16682454 [PubMed - indexed for MEDLINE]Related articlesFree article

Constitutive coactivator of peroxisome proliferator-activated receptor (PPARgamma), a novel coactivator of PPARgamma that promotes adipogenesis.

Li D, Kang Q, Wang DM.

Mol Endocrinol. 2007 Oct;21(10):2320-33. Epub 2007 Jun 26.PMID: 17595322 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity.

Schupp M, Clemenz M, Gineste R, Witt H, Janke J, Helleboid S, Hennuyer N, Ruiz P, Unger T, Staels B, Kintscher U.

Diabetes. 2005 Dec;54(12):3442-52.PMID: 16306360 [PubMed - indexed for MEDLINE]Related articlesFree article

PAR-1622 is a selective peroxisome proliferator-activated receptor gamma partial activator with preserved antidiabetic efficacy and broader safety profile for fluid retention.

Kim MK, Chae YN, Kim HS, Choi SH, Son MH, Kim SH, Kim JK, Moon HS, Park SK, Shin YA, Kim JG, Lee CH, Lim JI, Shin CY.

Arch Pharm Res. 2009 May;32(5):721-7. Epub 2009 May 27.PMID: 19471887 [PubMed - indexed for MEDLINE]Related articles

Unique properties of coactivator recruitment caused by differential binding of FK614, an anti-diabetic agent, to peroxisome proliferator-activated receptor gamma.

Fujimura T, Sakuma H, Ohkubo-Suzuki A, Aramori I, Mutoh S.

Biol Pharm Bull. 2006 Mar;29(3):423-9.PMID: 16508139 [PubMed - indexed for MEDLINE]Related articlesFree article

Fenofibrate prevents Rosiglitazone-induced body weight gain in ob/ob mice.

Carmona MC, Louche K, Nibbelink M, Prunet B, Bross A, Desbazeille M, Dacquet C, Renard P, Casteilla L, Pénicaud L.

Int J Obes (Lond). 2005 Jul;29(7):864-71.PMID: 15917863 [PubMed - indexed for MEDLINE]Related articles

Molecular activation of PPARgamma by angiotensin II type 1-receptor antagonists.

Erbe DV, Gartrell K, Zhang YL, Suri V, Kirincich SJ, Will S, Perreault M, Wang S, Tobin JF.

Vascul Pharmacol. 2006 Sep;45(3):154-62. Epub 2006 May 16.PMID: 16765099 [PubMed - indexed for MEDLINE]Related articles

A peroxisome proliferator-activated receptor gamma-retinoid X receptor heterodimer physically interacts with the transcriptional activator PAX6 to inhibit glucagon gene transcription.

Krätzner R, Fröhlich F, Lepler K, Schröder M, Röher K, Dickel C, Tzvetkov MV, Quentin T, Oetjen E, Knepel W.

Mol Pharmacol. 2008 Feb;73(2):509-17. Epub 2007 Oct 25.PMID: 17962386 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro.

Burgermeister E, Schnoebelen A, Flament A, Benz J, Stihle M, Gsell B, Rufer A, Ruf A, Kuhn B, Märki HP, Mizrahi J, Sebokova E, Niesor E, Meyer M.

Mol Endocrinol. 2006 Apr;20(4):809-30. Epub 2005 Dec 22.PMID: 16373399 [PubMed - indexed for MEDLINE]Related articlesFree article

KR-62980: a novel peroxisome proliferator-activated receptor gamma agonist with weak adipogenic effects.

Kim KR, Lee JH, Kim SJ, Rhee SD, Jung WH, Yang SD, Kim SS, Ahn JH, Cheon HG.

Biochem Pharmacol. 2006 Aug 14;72(4):446-54. Epub 2006 May 12.PMID: 16797489 [PubMed - indexed for MEDLINE]Related articles

Peroxisome proliferator-activated receptor gamma ligands suppress liver carcinogenesis induced by diethylnitrosamine in rats.

Guo YT, Leng XS, Li T, Zhao JM, Lin XH.

World J Gastroenterol. 2004 Dec 1;10(23):3419-23.PMID: 15526359 [PubMed - indexed for MEDLINE]Related articlesFree article

Different residues mediate recognition of 1-O-oleyllysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor gamma.

Tsukahara T, Tsukahara R, Yasuda S, Makarova N, Valentine WJ, Allison P, Yuan H, Baker DL, Li Z, Bittman R, Parrill A, Tigyi G.

J Biol Chem. 2006 Feb 10;281(6):3398-407. Epub 2005 Dec 1.PMID: 16321982 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential recruitment of the coactivator proteins CREB-binding protein and steroid receptor coactivator-1 to peroxisome proliferator-activated receptor gamma/9-cis-retinoic acid receptor heterodimers by ligands present in oxidized low-density lipoprotein.

Wigren J, Surapureddi S, Olsson AG, Glass CK, Hammarström S, Söderström M.

J Endocrinol. 2003 May;177(2):207-14.PMID: 12740008 [PubMed - indexed for MEDLINE]Related articlesFree article

INT131: a selective modulator of PPAR gamma.

Motani A, Wang Z, Weiszmann J, McGee LR, Lee G, Liu Q, Staunton J, Fang Z, Fuentes H, Lindstrom M, Liu J, Biermann DH, Jaen J, Walker NP, Learned RM, Chen JL, Li Y.

J Mol Biol. 2009 Mar 13;386(5):1301-11.PMID: 19452630 [PubMed - indexed for MEDLINE]Related articles

Ginsenoside 20S-protopanaxatriol (PPT) activates peroxisome proliferator-activated receptor gamma (PPARgamma) in 3T3-L1 adipocytes.

Han KL, Jung MH, Sohn JH, Hwang JK.

Biol Pharm Bull. 2006 Jan;29(1):110-3.PMID: 16394521 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulator.

Berger JP, Petro AE, Macnaul KL, Kelly LJ, Zhang BB, Richards K, Elbrecht A, Johnson BA, Zhou G, Doebber TW, Biswas C, Parikh M, Sharma N, Tanen MR, Thompson GM, Ventre J, Adams AD, Mosley R, Surwit RS, Moller DE.

Mol Endocrinol. 2003 Apr;17(4):662-76. Epub 2003 Jan 16.PMID: 12554792 [PubMed - indexed for MEDLINE]Related articlesFree article