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    Results: 1 to 20 of 271

    1.

    Evidence for a role of superoxide generation in glucose-induced beta-cell dysfunction in vivo.

    Tang C, Han P, Oprescu AI, Lee SC, Gyulkhandanyan AV, Chan GN, Wheeler MB, Giacca A.

    Diabetes. 2007 Nov;56(11):2722-31. Epub 2007 Aug 6.PMID: 17682092 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Free fatty acid-induced reduction in glucose-stimulated insulin secretion: evidence for a role of oxidative stress in vitro and in vivo.

    Oprescu AI, Bikopoulos G, Naassan A, Allister EM, Tang C, Park E, Uchino H, Lewis GF, Fantus IG, Rozakis-Adcock M, Wheeler MB, Giacca A.

    Diabetes. 2007 Dec;56(12):2927-37. Epub 2007 Aug 23.PMID: 17717282 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Antioxidants N-acetyl-L-cysteine and manganese(III)tetrakis (4-benzoic acid)porphyrin do not prevent beta-cell dysfunction in rat islets cultured in high glucose for 1 wk.

    Khaldi MZ, Elouil H, Guiot Y, Henquin JC, Jonas JC.

    Am J Physiol Endocrinol Metab. 2006 Jul;291(1):E137-46. Epub 2006 Feb 7.PMID: 16464909 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Mitochondrial reactive oxygen species are obligatory signals for glucose-induced insulin secretion.

    Leloup C, Tourrel-Cuzin C, Magnan C, Karaca M, Castel J, Carneiro L, Colombani AL, Ktorza A, Casteilla L, Pénicaud L.

    Diabetes. 2009 Mar;58(3):673-81. Epub 2008 Dec 10.PMID: 19073765 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    The role of phosphoinositide 3-kinase/Akt signaling in low-dose mercury-induced mouse pancreatic beta-cell dysfunction in vitro and in vivo.

    Chen YW, Huang CF, Tsai KS, Yang RS, Yen CC, Yang CY, Lin-Shiau SY, Liu SH.

    Diabetes. 2006 Jun;55(6):1614-24.PMID: 16731823 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    D-Glyceraldehyde causes production of intracellular peroxide in pancreatic islets, oxidative stress, and defective beta cell function via non-mitochondrial pathways.

    Takahashi H, Tran PO, LeRoy E, Harmon JS, Tanaka Y, Robertson RP.

    J Biol Chem. 2004 Sep 3;279(36):37316-23. Epub 2004 Jun 22.PMID: 15213233 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Oral taurine but not N-acetylcysteine ameliorates NEFA-induced impairment in insulin sensitivity and beta cell function in obese and overweight, non-diabetic men.

    Xiao C, Giacca A, Lewis GF.

    Diabetologia. 2008 Jan;51(1):139-46. Epub 2007 Nov 17.PMID: 18026714 [PubMed - indexed for MEDLINE]Related articles

    8.

    N-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible role of oxidative stress.

    Haber CA, Lam TK, Yu Z, Gupta N, Goh T, Bogdanovic E, Giacca A, Fantus IG.

    Am J Physiol Endocrinol Metab. 2003 Oct;285(4):E744-53. Epub 2003 Jun 10.PMID: 12799318 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Effects of hyperglycemia on angiotensin II receptor type 1 expression and insulin secretion in an INS-1E pancreatic beta-cell line.

    Leung KK, Leung PS.

    JOP. 2008 May 8;9(3):290-9.PMID: 18469441 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    PPARalpha activation reverses adverse effects induced by high-saturated-fat feeding on pancreatic beta-cell function in late pregnancy.

    Holness MJ, Smith ND, Greenwood GK, Sugden MC.

    Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1087-94. Epub 2006 Dec 12.PMID: 17164438 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Cyclical and alternating infusions of glucose and intralipid in rats inhibit insulin gene expression and Pdx-1 binding in islets.

    Hagman DK, Latour MG, Chakrabarti SK, Fontes G, Amyot J, Tremblay C, Semache M, Lausier JA, Roskens V, Mirmira RG, Jetton TL, Poitout V.

    Diabetes. 2008 Feb;57(2):424-31. Epub 2007 Nov 8.PMID: 17991758 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Nicorandil improves diabetes and rat islet beta-cell damage induced by streptozotocin in vivo and in vitro.

    Kasono K, Yasu T, Kakehashi A, Kinoshita N, Tamemoto H, Namai K, Ohno R, Ueba H, Kuroki M, Ishikawa S, Kawakami M.

    Eur J Endocrinol. 2004 Aug;151(2):277-85.PMID: 15296485 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    In vivo and in vitro increased pancreatic beta-cell sensitivity to glucose in normal rats submitted to a 48-h hyperglycaemic period.

    Thibault C, Guettet C, Laury MC, N'Guyen JM, Tormo MA, Bailbé D, Portha B, Pénicaud L, Ktorza A.

    Diabetologia. 1993 Jul;36(7):589-95.PMID: 8359576 [PubMed - indexed for MEDLINE]Related articles

    14.

    HIV-1 protease inhibitor induced oxidative stress suppresses glucose stimulated insulin release: protection with thymoquinone.

    Chandra S, Mondal D, Agrawal KC.

    Exp Biol Med (Maywood). 2009 Apr;234(4):442-53. Epub 2009 Feb 20.PMID: 19234050 [PubMed - indexed for MEDLINE]Related articles

    15.

    Glucose suppresses superoxide generation in metabolically responsive pancreatic beta cells.

    Martens GA, Cai Y, Hinke S, Stangé G, Van de Casteele M, Pipeleers D.

    J Biol Chem. 2005 May 27;280(21):20389-96. Epub 2005 Mar 17.PMID: 15774474 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species.

    Lin Y, Berg AH, Iyengar P, Lam TK, Giacca A, Combs TP, Rajala MW, Du X, Rollman B, Li W, Hawkins M, Barzilai N, Rhodes CJ, Fantus IG, Brownlee M, Scherer PE.

    J Biol Chem. 2005 Feb 11;280(6):4617-26. Epub 2004 Nov 9.PMID: 15536073 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Lipid-induced beta-cell dysfunction in vivo in models of progressive beta-cell failure.

    Goh TT, Mason TM, Gupta N, So A, Lam TK, Lam L, Lewis GF, Mari A, Giacca A.

    Am J Physiol Endocrinol Metab. 2007 Feb;292(2):E549-60. Epub 2006 Sep 26.PMID: 17003242 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Reactive oxygen species modulate coronary wall shear stress and endothelial function during hyperglycemia.

    Gross ER, LaDisa JF Jr, Weihrauch D, Olson LE, Kress TT, Hettrick DA, Pagel PS, Warltier DC, Kersten JR.

    Am J Physiol Heart Circ Physiol. 2003 May;284(5):H1552-9. Epub 2003 Jan 23.PMID: 12543642 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Src activation generates reactive oxygen species and impairs metabolism-secretion coupling in diabetic Goto-Kakizaki and ouabain-treated rat pancreatic islets.

    Kominato R, Fujimoto S, Mukai E, Nakamura Y, Nabe K, Shimodahira M, Nishi Y, Funakoshi S, Seino Y, Inagaki N.

    Diabetologia. 2008 Jul;51(7):1226-35. Epub 2008 May 1.PMID: 18449527 [PubMed - indexed for MEDLINE]Related articles

    20.

    Mitochondrial superoxide plays a crucial role in the development of mitochondrial dysfunction during high glucose exposure in rat renal proximal tubular cells.

    Munusamy S, MacMillan-Crow LA.

    Free Radic Biol Med. 2009 Apr 15;46(8):1149-57. Epub 2009 Feb 3.PMID: 19439219 [PubMed - indexed for MEDLINE]Related articles

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