PubMed

Evidence for vasculoprotective effects of ETB receptors in resistance artery remodeling in diabetes.

Sachidanandam K, Portik-Dobos V, Harris AK, Hutchinson JR, Muller E, Johnson MH, Ergul A.

Diabetes. 2007 Nov;56(11):2753-8. Epub 2007 Aug 1.PMID: 17670915 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycemic control prevents microvascular remodeling and increased tone in type 2 diabetes: link to endothelin-1.

Sachidanandam K, Hutchinson JR, Elgebaly MM, Mezzetti EM, Dorrance AM, Motamed K, Ergul A.

Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R952-9. Epub 2009 Jan 28.PMID: 19176890 [PubMed - indexed for MEDLINE]Related articles

Type 2 diabetes causes remodeling of cerebrovasculature via differential regulation of matrix metalloproteinases and collagen synthesis: role of endothelin-1.

Harris AK, Hutchinson JR, Sachidanandam K, Johnson MH, Dorrance AM, Stepp DW, Fagan SC, Ergul A.

Diabetes. 2005 Sep;54(9):2638-44.PMID: 16123352 [PubMed - indexed for MEDLINE]Related articlesFree article

Type-2 diabetes-induced changes in vascular extracellular matrix gene expression: relation to vessel size.

Song W, Ergul A.

Cardiovasc Diabetol. 2006 Feb 17;5:3.PMID: 16503991 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of ET(A) and ET(B) receptor antagonism on oxidative stress in type 2 diabetes.

Elgebaly MM, Portik-Dobos V, Sachidanandam K, Rychly D, Malcom D, Johnson MH, Ergul A.

Vascul Pharmacol. 2007 Aug-Sep;47(2-3):125-30. Epub 2007 Jun 6.PMID: 17597010 [PubMed - indexed for MEDLINE]Related articles

Effect of chronic and selective endothelin receptor antagonism on microvascular function in type 2 diabetes.

Sachidanandam K, Elgebaly MM, Harris AK, Hutchinson JR, Mezzetti EM, Portik-Dobos V, Ergul A.

Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2743-9. Epub 2008 Apr 18.PMID: 18424628 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of chronic endothelin receptor antagonism on cerebrovascular function in type 2 diabetes.

Harris AK, Elgebaly MM, Li W, Sachidanandam K, Ergul A.

Am J Physiol Regul Integr Comp Physiol. 2008 Apr;294(4):R1213-9. Epub 2008 Feb 20.PMID: 18287215 [PubMed - indexed for MEDLINE]Related articles

Differential effects of diet-induced dyslipidemia and hyperglycemia on mesenteric resistance artery structure and function in type 2 diabetes.

Sachidanandam K, Hutchinson JR, Elgebaly MM, Mezzetti EM, Wang MH, Ergul A.

J Pharmacol Exp Ther. 2009 Jan;328(1):123-30. Epub 2008 Oct 21.PMID: 18941121 [PubMed - indexed for MEDLINE]Related articles

Microvascular versus macrovascular dysfunction in type 2 diabetes: differences in contractile responses to endothelin-1.

Sachidanandam K, Harris A, Hutchinson J, Ergul A.

Exp Biol Med (Maywood). 2006 Jun;231(6):1016-21.PMID: 16741041 [PubMed - indexed for MEDLINE]Related articlesFree article

The vasoconstriction induced by endothelin-1 is mediated only by ET(A) receptors in mesenteric small resistance arteries of spontaneously hypertensive rats and Wistar Kyoto rats.

Rizzoni D, Porteri E, Piccoli A, Castellano M, Bettoni G, Pasini G, Agabiti-Rosei E.

J Hypertens. 1997 Dec;15(12 Pt 2):1653-7.PMID: 9488218 [PubMed - indexed for MEDLINE]Related articles

Stress upregulates arterial matrix metalloproteinase expression and activity via endothelin A receptor activation.

Ergul A, Portik-Dobos V, Giulumian AD, Molero MM, Fuchs LC.

Am J Physiol Heart Circ Physiol. 2003 Nov;285(5):H2225-32. Epub 2003 Jul 3.PMID: 12842810 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired insulin-mediated vasorelaxation in a nonobese model of type 2 diabetes: role of endothelin-1.

Elgebaly MM, Kelly A, Harris AK, Elewa H, Portik-Dobos V, Ketsawatsomkron P, Marrero M, Ergul A.

Can J Physiol Pharmacol. 2008 Jun;86(6):358-64.PMID: 18516099 [PubMed - indexed for MEDLINE]Related articles

Endothelin antagonism prevents early EGFR transactivation but not increased matrix metalloproteinase activity in diabetes.

Portik-Dobos V, Harris AK, Song W, Hutchinson J, Johnson MH, Imig JD, Pollock DM, Ergul A.

Am J Physiol Regul Integr Comp Physiol. 2006 Feb;290(2):R435-41. Epub 2005 Oct 20.PMID: 16239374 [PubMed - indexed for MEDLINE]Related articles

Interleukin-10 attenuates vascular responses to endothelin-1 via effects on ERK1/2-dependent pathway.

Giachini FR, Zemse SM, Carneiro FS, Lima VV, Carneiro ZN, Callera GE, Ergul A, Webb RC, Tostes RC.

Am J Physiol Heart Circ Physiol. 2009 Feb;296(2):H489-96. Epub 2008 Dec 12.PMID: 19074677 [PubMed - indexed for MEDLINE]Related articles

Comparison of the contractile and calcium-increasing properties of platelet-activating factor and endothelin-1 in the rat mesenteric artery and vein.

Claing A, Shbaklo H, Plante M, Bkaily G, D'Orléans-Juste P.

Br J Pharmacol. 2002 Jan;135(2):433-43.PMID: 11815379 [PubMed - indexed for MEDLINE]Related articlesFree article

Remodeling of resistance arteries in renal failure: effect of endothelin receptor blockade.

Amann K, Miltenberger-Miltenyi G, Simonoviciene A, Koch A, Orth S, Ritz E.

J Am Soc Nephrol. 2001 Oct;12(10):2040-50.PMID: 11562402 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelin-1-induced pulmonary vasoreactivity is regulated by ET(A) and ET(B) receptor interactions.

Sauvageau S, Thorin E, Caron A, Dupuis J.

J Vasc Res. 2007;44(5):375-81. Epub 2007 May 8.PMID: 17495482 [PubMed - indexed for MEDLINE]Related articles

Calcitonin gene-related peptide selectively relaxes contractile responses to endothelin-1 in rat mesenteric resistance arteries.

Meens MJ, Fazzi GE, van Zandvoort MA, De Mey JG.

J Pharmacol Exp Ther. 2009 Oct;331(1):87-95. Epub 2009 Jul 23.PMID: 19628632 [PubMed - indexed for MEDLINE]Related articles

Bradykinin and matrix metalloproteinases are involved the structural alterations of rat small resistance arteries with inhibition of ACE and NEP.

Rizzoni D, Rossi GP, Porteri E, Sticchi D, Rodella L, Rezzani R, Sleiman I, De Ciuceis C, Paiardi S, Bianchi R, Nussdorfer GG, Agabiti-Rosei E.

J Hypertens. 2004 Apr;22(4):759-66.PMID: 15126918 [PubMed - indexed for MEDLINE]Related articles

ET(B) receptor-deficient rats exhibit reduced contraction to ET-1 despite an increase in ET(A) receptors.

Perry MG, Molero MM, Giulumian AD, Katakam PV, Pollock JS, Pollock DM, Fuchs LC.

Am J Physiol Heart Circ Physiol. 2001 Dec;281(6):H2680-6.PMID: 11709437 [PubMed - indexed for MEDLINE]Related articlesFree article