PubMed

Pioglitazone use and heart failure in patients with type 2 diabetes and preexisting cardiovascular disease: data from the PROactive study (PROactive 08).

Erdmann E, Charbonnel B, Wilcox RG, Skene AM, Massi-Benedetti M, Yates J, Tan M, Spanheimer R, Standl E, Dormandy JA; PROactive investigators.

Diabetes Care. 2007 Nov;30(11):2773-8. Epub 2007 Jul 31.PMID: 17666462 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of pioglitazone on recurrent myocardial infarction in 2,445 patients with type 2 diabetes and previous myocardial infarction: results from the PROactive (PROactive 05) Study.

Erdmann E, Dormandy JA, Charbonnel B, Massi-Benedetti M, Moules IK, Skene AM; PROactive Investigators.

J Am Coll Cardiol. 2007 May 1;49(17):1772-80. Epub 2007 Apr 16.PMID: 17466227 [PubMed - indexed for MEDLINE]Related articles

Safety and tolerability of pioglitazone in high-risk patients with type 2 diabetes: an overview of data from PROactive.

Dormandy J, Bhattacharya M, van Troostenburg de Bruyn AR; PROactive investigators.

Drug Saf. 2009;32(3):187-202. doi: 10.2165/00002018-200932030-00002. Review.PMID: 19338377 [PubMed - indexed for MEDLINE]Related articles

Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of randomized trials.

Lincoff AM, Wolski K, Nicholls SJ, Nissen SE.

JAMA. 2007 Sep 12;298(10):1180-8.PMID: 17848652 [PubMed - indexed for MEDLINE]Related articlesFree article

The prospective pioglitazone clinical trial in macrovascular events (PROactive): can pioglitazone reduce cardiovascular events in diabetes? Study design and baseline characteristics of 5238 patients.

Charbonnel B, Dormandy J, Erdmann E, Massi-Benedetti M, Skene A; PROactive Study Group.

Diabetes Care. 2004 Jul;27(7):1647-53.PMID: 15220241 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of pioglitazone in patients with type 2 diabetes with or without previous stroke: results from PROactive (PROspective pioglitAzone Clinical Trial In macroVascular Events 04).

Wilcox R, Bousser MG, Betteridge DJ, Schernthaner G, Pirags V, Kupfer S, Dormandy J; PROactive Investigators.

Stroke. 2007 Mar;38(3):865-73. Epub 2007 Feb 8.PMID: 17290029 [PubMed - indexed for MEDLINE]Related articlesFree article

Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial.

Dormandy JA, Charbonnel B, Eckland DJ, Erdmann E, Massi-Benedetti M, Moules IK, Skene AM, Tan MH, Lefèbvre PJ, Murray GD, Standl E, Wilcox RG, Wilhelmsen L, Betteridge J, Birkeland K, Golay A, Heine RJ, Korányi L, Laakso M, Mokán M, Norkus A, Pirags V, Podar T, Scheen A, Scherbaum W, Schernthaner G, Schmitz O, Skrha J, Smith U, Taton J; PROactive investigators.

Lancet. 2005 Oct 8;366(9493):1279-89.PMID: 16214598 [PubMed - indexed for MEDLINE]Related articles

Effects of pioglitazone on major adverse cardiovascular events in high-risk patients with type 2 diabetes: results from PROspective pioglitAzone Clinical Trial In macro Vascular Events (PROactive 10).

Wilcox R, Kupfer S, Erdmann E; PROactive Study investigators.

Am Heart J. 2008 Apr;155(4):712-7. Epub 2008 Feb 21. Erratum in: Am Heart J. 2008 Aug;156(2):255. PMID: 18371481 [PubMed - indexed for MEDLINE]Related articles

PROactive 06: cost-effectiveness of pioglitazone in Type 2 diabetes in the UK.

Valentine WJ, Bottomley JM, Palmer AJ, Brändle M, Foos V, Williams R, Dormandy JA, Yates J, Tan MH, Massi-Benedetti M; PROactive Study Group.

Diabet Med. 2007 Sep;24(9):982-1002. Epub 2007 Jun 25.PMID: 17593245 [PubMed - indexed for MEDLINE]Related articles

Pioglitazone and cardiovascular risk. A comprehensive meta-analysis of randomized clinical trials.

Mannucci E, Monami M, Lamanna C, Gensini GF, Marchionni N.

Diabetes Obes Metab. 2008 Dec;10(12):1221-38. Epub 2008 May 26. Review.PMID: 18505403 [PubMed - indexed for MEDLINE]Related articles

Thiazolidinediones in type 2 diabetes: a cardiology perspective.

Khanderia U, Pop-Busui R, Eagle KA.

Ann Pharmacother. 2008 Oct;42(10):1466-74. Epub 2008 Sep 2. Review.PMID: 18698014 [PubMed - indexed for MEDLINE]Related articles

[Proactive study: secondary cardiovascular prevention with pioglitazione in type 2 diabetic patients]

Scheen AJ, Lefèbvre PJ.

Rev Med Liege. 2005 Nov;60(11):896-901. French. PMID: 16402538 [PubMed - indexed for MEDLINE]Related articles

Association between congestive heart failure and hospitalization in patients with type 2 diabetes mellitus receiving treatment with insulin or pioglitazone: a retrospective data analysis.

Rajagopalan R, Rosenson RS, Fernandes AW, Khan M, Murray FT.

Clin Ther. 2004 Sep;26(9):1400-10.PMID: 15531002 [PubMed - indexed for MEDLINE]Related articles

Effect of pioglitazone on cardiovascular outcome in diabetes and chronic kidney disease.

Schneider CA, Ferrannini E, Defronzo R, Schernthaner G, Yates J, Erdmann E.

J Am Soc Nephrol. 2008 Jan;19(1):182-7. Epub 2007 Dec 5.PMID: 18057215 [PubMed - indexed for MEDLINE]Related articlesFree article

[Trial of pioglitazone for the secondary prevention of cardiovascular events in patients with diabetes mellitus type 2: insufficient evidence]

Holleman F, Gerdes VE, de Vries JH, Hoekstra JB.

Ned Tijdschr Geneeskd. 2006 Feb 18;150(7):358-60. Dutch. PMID: 16523797 [PubMed - indexed for MEDLINE]Related articles

Long-term risk of cardiovascular events with rosiglitazone: a meta-analysis.

Singh S, Loke YK, Furberg CD.

JAMA. 2007 Sep 12;298(10):1189-95.PMID: 17848653 [PubMed - indexed for MEDLINE]Related articlesFree article

[Glitazones and congestive heart failure: update on PROactive, ADOPT, DREAM and RECORD clinical trials]

De Flines J, Scheen AJ.

Rev Med Suisse. 2007 Aug 29;3(122):1876, 1878-83. Review. French. PMID: 17896661 [PubMed - indexed for MEDLINE]Related articles

Rosiglitazone and pioglitazone utilization from January 2007 through May 2008 associated with five risk-warning events.

Starner CI, Schafer JA, Heaton AH, Gleason PP.

J Manag Care Pharm. 2008 Jul-Aug;14(6):523-31.PMID: 18693776 [PubMed - indexed for MEDLINE]Related articlesFree article

Adverse cardiovascular events during treatment with pioglitazone and rosiglitazone: population based cohort study.

Juurlink DN, Gomes T, Lipscombe LL, Austin PC, Hux JE, Mamdani MM.

BMJ. 2009 Aug 18;339:b2942. doi: 10.1136/bmj.b2942.PMID: 19690342 [PubMed - indexed for MEDLINE]Related articlesFree article

Thiazolidinediones in patients with diabetes mellitus and heart failure : implications of emerging data.

Macfarlane DP, Fisher M.

Am J Cardiovasc Drugs. 2006;6(5):297-304. Review.PMID: 17083264 [PubMed - indexed for MEDLINE]Related articles