PubMed

Farnesoid X receptor modulates renal lipid metabolism, fibrosis, and diabetic nephropathy.

Jiang T, Wang XX, Scherzer P, Wilson P, Tallman J, Takahashi H, Li J, Iwahashi M, Sutherland E, Arend L, Levi M.

Diabetes. 2007 Oct;56(10):2485-93. Epub 2007 Jul 27.PMID: 17660268 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes.

Proctor G, Jiang T, Iwahashi M, Wang Z, Li J, Levi M.

Diabetes. 2006 Sep;55(9):2502-9.PMID: 16936198 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVBdb/db mice with type 2 diabetes.

Wang Z, Jiang T, Li J, Proctor G, McManaman JL, Lucia S, Chua S, Levi M.

Diabetes. 2005 Aug;54(8):2328-35.PMID: 16046298 [PubMed - indexed for MEDLINE]Related articlesFree article

The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria.

Wang XX, Jiang T, Shen Y, Adorini L, Pruzanski M, Gonzalez FJ, Scherzer P, Lewis L, Miyazaki-Anzai S, Levi M.

Am J Physiol Renal Physiol. 2009 Dec;297(6):F1587-96. Epub 2009 Sep 23.PMID: 19776172 [PubMed - in process]Related articles

Antiatherosclerotic effect of farnesoid X receptor.

Mencarelli A, Renga B, Distrutti E, Fiorucci S.

Am J Physiol Heart Circ Physiol. 2009 Feb;296(2):H272-81. Epub 2008 Nov 21.PMID: 19028791 [PubMed - indexed for MEDLINE]Related articles

Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1c-dependent pathway.

Jiang T, Wang Z, Proctor G, Moskowitz S, Liebman SE, Rogers T, Lucia MS, Li J, Levi M.

J Biol Chem. 2005 Sep 16;280(37):32317-25. Epub 2005 Jul 25.PMID: 16046411 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of drug transporters by the farnesoid X receptor in mice.

Maeda T, Miyata M, Yotsumoto T, Kobayashi D, Nozawa T, Toyama K, Gonzalez FJ, Yamazoe Y, Tamai I.

Mol Pharm. 2004 Jul-Aug;1(4):281-9.PMID: 15981587 [PubMed - indexed for MEDLINE]Related articles

Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression.

Claudel T, Inoue Y, Barbier O, Duran-Sandoval D, Kosykh V, Fruchart J, Fruchart JC, Gonzalez FJ, Staels B.

Gastroenterology. 2003 Aug;125(2):544-55.PMID: 12891557 [PubMed - indexed for MEDLINE]Related articles

A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids.

Shih DM, Kast-Woelbern HR, Wong J, Xia YR, Edwards PA, Lusis AJ.

J Lipid Res. 2006 Feb;47(2):384-92. Epub 2005 Nov 3.PMID: 16269825 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of carbohydrate metabolism by the farnesoid X receptor.

Stayrook KR, Bramlett KS, Savkur RS, Ficorilli J, Cook T, Christe ME, Michael LF, Burris TP.

Endocrinology. 2005 Mar;146(3):984-91. Epub 2004 Nov 24.PMID: 15564327 [PubMed - indexed for MEDLINE]Related articlesFree article

The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors.

Ricketts ML, Boekschoten MV, Kreeft AJ, Hooiveld GJ, Moen CJ, Müller M, Frants RR, Kasanmoentalib S, Post SM, Princen HM, Porter JG, Katan MB, Hofker MH, Moore DD.

Mol Endocrinol. 2007 Jul;21(7):1603-16. Epub 2007 Apr 24.PMID: 17456796 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of bile acids and bile acid receptors in metabolic regulation.

Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B.

Physiol Rev. 2009 Jan;89(1):147-91. Review.PMID: 19126757 [PubMed - indexed for MEDLINE]Related articles

Farnesoid X receptor deficiency induces nonalcoholic steatohepatitis in low-density lipoprotein receptor-knockout mice fed a high-fat diet.

Kong B, Luyendyk JP, Tawfik O, Guo GL.

J Pharmacol Exp Ther. 2009 Jan;328(1):116-22. Epub 2008 Oct 23.PMID: 18948497 [PubMed - indexed for MEDLINE]Related articles

Suppression of interleukin-6-induced C-reactive protein expression by FXR agonists.

Zhang S, Liu Q, Wang J, Harnish DC.

Biochem Biophys Res Commun. 2009 Feb 6;379(2):476-9. Epub 2008 Dec 30.PMID: 19118524 [PubMed - indexed for MEDLINE]Related articles

Role of sterol regulatory element-binding protein 1 in regulation of renal lipid metabolism and glomerulosclerosis in diabetes mellitus.

Sun L, Halaihel N, Zhang W, Rogers T, Levi M.

J Biol Chem. 2002 May 24;277(21):18919-27. Epub 2002 Mar 1.PMID: 11875060 [PubMed - indexed for MEDLINE]Related articlesFree article

Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development.

Maran RR, Thomas A, Roth M, Sheng Z, Esterly N, Pinson D, Gao X, Zhang Y, Ganapathy V, Gonzalez FJ, Guo GL.

J Pharmacol Exp Ther. 2009 Feb;328(2):469-77. Epub 2008 Nov 3.PMID: 18981289 [PubMed - indexed for MEDLINE]Related articles

Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice.

Zhang Y, Lee FY, Barrera G, Lee H, Vales C, Gonzalez FJ, Willson TM, Edwards PA.

Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):1006-11. Epub 2006 Jan 12.PMID: 16410358 [PubMed - indexed for MEDLINE]Related articlesFree article

The farnesoid X receptor (FXR) as a new target in non-alcoholic steatohepatitis.

Cariou B.

Diabetes Metab. 2008 Dec;34(6 Pt 2):685-91.PMID: 19195631 [PubMed - indexed for MEDLINE]Related articles

FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine.

Lee H, Zhang Y, Lee FY, Nelson SF, Gonzalez FJ, Edwards PA.

J Lipid Res. 2006 Jan;47(1):201-14. Epub 2005 Oct 26.PMID: 16251721 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine.

Zollner G, Fickert P, Fuchsbichler A, Silbert D, Wagner M, Arbeiter S, Gonzalez FJ, Marschall HU, Zatloukal K, Denk H, Trauner M.

J Hepatol. 2003 Oct;39(4):480-8.PMID: 12971955 [PubMed - indexed for MEDLINE]Related articles